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  1. Research article

    Acute Penicillium marneffei infection stimulates host M1/M2a macrophages polarization in BALB/C mice

    Penicillium marneffei (P. marneffei) is a thermally dimorphic fungus pathogen that causes fatal infection. Alveolar macrophages are innate immune cells that have critical roles in prot...

    Xiaoying Dai, Congzheng Mao, Xiuwan Lan, Huan Chen, Meihua Li, Jing Bai, Jingmin Deng, Qiuli Liang, Jianquan Zhang, Xiaoning Zhong, Yi Liang, Jiangtao Fan, Honglin Luo and Zhiyi He

    BMC Microbiology 2017 17:177

    Published on: 18 August 2017

  2. Research article

    Differences in survival, virulence and biofilm formation between sialidase-deficient and W83 wild-type Porphyromonas gingivalis strains under stressful environmental conditions

    Porphyromonas gingivalis is a major causative pathogen of chronic periodontitis. Within the inflammatory microenvironment, there exists extreme pH values, elevated temperatures and oxi...

    Xiaoyu Xu, Tong Tong, Xue Yang, Yaping Pan, Li Lin and Chen Li

    BMC Microbiology 2017 17:178

    Published on: 18 August 2017

  3. Research article

    Genetic diversity and virulence potential of clinical and environmental Aeromonas spp. isolates from a diarrhea outbreak

    Aeromonas spp. are gram-negative bacteria that can cause a variety of infections in both humans and animals and play a controversial role in diarrhea outbreaks. Our aim was to identify...

    Lívia Christina Alves da Silva, Tereza Cristina Leal-Balbino, Beatriz Souza Toscano de Melo, Carina Lucena Mendes-Marques, Antonio Mauro Rezende, Alzira Maria Paiva de Almeida and Nilma Cintra Leal

    BMC Microbiology 2017 17:179

    Published on: 18 August 2017

  4. Research article

    Administration of two probiotic strains during early childhood does not affect the endogenous gut microbiota composition despite probiotic proliferation

    Probiotics are increasingly applied to prevent and treat a range of infectious, immune related and gastrointestinal diseases. Despite this, the mechanisms behind the putative effects of probiotics are poorly u...

    Martin Frederik Laursen, Rikke Pilmann Laursen, Anni Larnkjær, Kim F. Michaelsen, Martin Iain Bahl and Tine Rask Licht

    BMC Microbiology 2017 17:175

    Published on: 17 August 2017

  5. Research article

    Proteomic analysis during of spore germination of Moniliophthora perniciosa, the causal agent of witches’ broom disease in cacao

    Moniliophthora perniciosa is a phytopathogenic fungus responsible for witches’ broom disease of cacao trees (Theobroma cacao L.). Understanding the molecular events during germination ...

    Joise Hander Mares, Karina Peres Gramacho, Everton Cruz Santos, André da Silva Santiago, Juliano Oliveira Santana, Aurizângela Oliveira de Sousa, Fátima Cerqueira Alvim and Carlos Priminho Pirovani

    BMC Microbiology 2017 17:176

    Published on: 17 August 2017

  6. Research article

    Environmentally triggered genomic plasticity and capsular polysaccharide formation are involved in increased ethanol and acetic acid tolerance in Kozakia baliensis NBRC 16680

    Kozakia baliensis NBRC 16680 secretes a gum-cluster derived heteropolysaccharide and forms a surface pellicle composed of polysaccharides during static cultivation. Furthermore, this s...

    Julia U. Brandt, Friederike-Leonie Born, Frank Jakob and Rudi F. Vogel

    BMC Microbiology 2017 17:172

    Published on: 10 August 2017

  7. Research article

    Development of a new fluorescent reporter:operator system: location of AraC regulated genes in Escherichia coli K-12

    In bacteria, many transcription activator and repressor proteins regulate multiple transcription units that are often distally distributed on the bacterial genome. To investigate the subcellular location of DN...

    Laura E. Sellars, Jack A. Bryant, María-Antonia Sánchez-Romero, Eugenio Sánchez-Morán, Stephen J. W. Busby and David J. Lee

    BMC Microbiology 2017 17:170

    Published on: 3 August 2017

  8. Research article

    Biogeographical distribution analysis of hydrocarbon degrading and biosurfactant producing genes suggests that near-equatorial biomes have higher abundance of genes with potential for bioremediation

    Bacterial and Archaeal communities have a complex, symbiotic role in crude oil bioremediation. Their biosurfactants and degradation enzymes have been in the spotlight, mainly due to the awareness of ecosystem ...

    Jorge S. Oliveira, Wydemberg J. Araújo, Ricardo M. Figueiredo, Rita C. B. Silva-Portela, Alaine de Brito Guerra, Sinara Carla da Silva Araújo, Carolina Minnicelli, Aline Cardoso Carlos, Ana Tereza Ribeiro de Vasconcelos, Ana Teresa Freitas and Lucymara F. Agnez-Lima

    BMC Microbiology 2017 17:168

    Published on: 27 July 2017

  9. Research article

    Re-classification within the serogroups O3 and O8 of Citrobacter strains

    Citrobacter strains are opportunistic pathogens often responsible for serious enteric as well as extra-intestinal diseases, and therefore the O-antigenic scheme, still in use in diagno...

    Ewa Katzenellenbogen, Magdalena Staniszewska, Nina A. Kocharova, Małgorzata Mieszała, Agnieszka Korzeniowska-Kowal, Sabina Górska, Yuriy A. Knirel and Andrzej Gamian

    BMC Microbiology 2017 17:169

    Published on: 27 July 2017

    The Erratum to this article has been published in BMC Microbiology 2017 17:173

  10. Research article

    Anaerobic bacteria growth in the presence of cathelicidin LL-37 and selected ceragenins delivered as magnetic nanoparticles cargo

    Cationic antibacterial peptides (CAPs) and synthetic molecules mimicking the amphiphilic structure of CAPs, such as ceragenins, are promising compounds for the development of new antimicrobials.

    Bonita Durnaś, Ewelina Piktel, Marzena Wątek, Tomasz Wollny, Stanisław Góźdź, Jolanta Smok-Kalwat, Katarzyna Niemirowicz, Paul B. Savage and Robert Bucki

    BMC Microbiology 2017 17:167

    Published on: 26 July 2017

  11. Research article

    Acid tolerance properties of dental biofilms in vivo

    The ecological plaque hypothesis explains caries development as the result of the enrichment of acid tolerant bacteria in dental biofilms in response to prolonged periods of low pH. Acid production by an acid ...

    A Senneby, JR Davies, G Svensäter and J Neilands

    BMC Microbiology 2017 17:165

    Published on: 25 July 2017

  12. Methodology Article

    Improved detection of genus-specific Alphavirus using a generic TaqMan® assay

    Alphaviruses are arthropod borne RNA viruses of medical importance. Geographical expansion of mosquitoes of the Aedes genus in the past decades has been associated with major Alphavirus-associated outbreaks. Clim...

    Claude Giry, Bénédicte Roquebert, Ghislaine Li-Pat-Yuen, Philippe Gasque and Marie-Christine Jaffar-Bandjee

    BMC Microbiology 2017 17:164

    Published on: 24 July 2017

  13. Research article

    An integrated computational-experimental approach reveals Yersinia pestis genes essential across a narrow or a broad range of environmental conditions

    The World Health Organization has categorized plague as a re-emerging disease and the potential for Yersinia pestis to also be used as a bioweapon makes the identification of new drug targets against this pathoge...

    Nicola J. Senior, Kalesh Sasidharan, Richard J. Saint, Andrew E. Scott, Mitali Sarkar-Tyson, Philip M. Ireland, Helen L Bullifent, Z. Rong Yang, Karen Moore, Petra C. F. Oyston, Timothy P. Atkins, Helen S. Atkins, Orkun S. Soyer and Richard W. Titball

    BMC Microbiology 2017 17:163

    Published on: 21 July 2017

  14. Research article

    16S rRNA gene-based association study identified microbial taxa associated with pork intramuscular fat content in feces and cecum lumen

    Intramuscular fat (IMF) that deposits among muscle fibers or within muscle cells is an important meat quality trait in pigs. Previous studies observed the effects of dietary nutrients and additives on improvin...

    Shaoming Fang, Xingwei Xiong, Ying Su, Lusheng Huang and Congying Chen

    BMC Microbiology 2017 17:162

    Published on: 19 July 2017

  15. Research article

    Sequence-based identification of inositol monophosphatase-like histidinol-phosphate phosphatases (HisN) in Corynebacterium glutamicum, Actinobacteria, and beyond

    The eighth step of l-histidine biosynthesis is carried out by an enzyme called histidinol-phosphate phosphatase (HolPase). Three unrelated HolPase families are known so far. Two of them are well studied: HAD-type...

    Robert Kasimir Kulis-Horn, Christian Rückert, Jörn Kalinowski and Marcus Persicke

    BMC Microbiology 2017 17:161

    Published on: 18 July 2017

  16. Research article

    The human jejunum has an endogenous microbiota that differs from those in the oral cavity and colon

    The upper half of the human small intestine, known as the jejunum, is the primary site for absorption of nutrient-derived carbohydrates, amino acids, small peptides, and vitamins. In contrast to the colon, whi...

    Olof H. Sundin, Antonio Mendoza-Ladd, Mingtao Zeng, Diana Diaz-Arévalo, Elisa Morales, B. Matthew Fagan, Javier Ordoñez, Philip Velez, Nishaal Antony and Richard W. McCallum

    BMC Microbiology 2017 17:160

    Published on: 17 July 2017

  17. Research article

    Broad-range potential of Asphodelus microcarpus leaves extract for drug development

    Many plants have been used in traditional medicine for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, anti-inflammatory and anticancer activities.

    Amalia Di Petrillo, Antonella Fais, Francesca Pintus, Celestino Santos-Buelga, Ana M. González-Paramás, Vincenzo Piras, Germano Orrù, Antonello Mameli, Enzo Tramontano and Aldo Frau

    BMC Microbiology 2017 17:159

    Published on: 14 July 2017

  18. Research article

    Physiological roles of sigma factor SigD in Corynebacterium glutamicum

    Sigma factors are one of the components of RNA polymerase holoenzymes, and an essential factor of transcription initiation in bacteria. Corynebacterium glutamicum possesses seven genes coding for sigma factors, m...

    Hironori Taniguchi, Tobias Busche, Thomas Patschkowski, Karsten Niehaus, Miroslav Pátek, Jörn Kalinowski and Volker F. Wendisch

    BMC Microbiology 2017 17:158

    Published on: 12 July 2017

  19. Research article

    Hypothetical protein Cpn0423 triggers NOD2 activation and contributes to Chlamydia pneumoniae-mediated inflammation

    Chlamydia pneumoniae (C. pneumoniae) is pathogenic to humans, by causing pulmonary inflammation or bronchitis in both adolescents and young adults. However, the molecular signals linki...

    Hong-liang Chen, Guo-zhi Dai, An-wen Zhou, Ran-hui Li, Hong-xia Yuan, Jing Xiang, Xiao-xing You, Ou Ran and Yi-mou Wu

    BMC Microbiology 2017 17:153

    Published on: 11 July 2017

  20. Research article

    Bacillus subtilis IolQ (DegA) is a transcriptional repressor of iolX encoding NAD+-dependent scyllo-inositol dehydrogenase

    Bacillus subtilis is able to utilize at least three inositol stereoisomers as carbon sources, myo-, scyllo-, and D-chiro-inositol (MI, SI, and DCI, respectively). NAD+-dependent SI deh...

    Dong-Min Kang, Christophe Michon, Tetsuro Morinaga, Kosei Tanaka, Shinji Takenaka, Shu Ishikawa and Ken-ichi Yoshida

    BMC Microbiology 2017 17:154

    Published on: 11 July 2017

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