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  1. Bacterial plasmids often carry antibiotic resistance genes and are a significant factor in the spread of antibiotic resistance. The ability to completely assemble plasmid sequences would facilitate the localiz...

    Authors: Astrid P. Heikema, Rick Jansen, Saskia D. Hiltemann, John P. Hays and Andrew P. Stubbs

    Citation: BMC Microbiology 2021 21:171

    Content type: Software

    Published on:

  2. The unique climatic conditions of the Xinjiang region nurture rich melon and fruit resources, the melon and fruit sugar sources provide sufficient nutrients for the survival of yeast, and the diverse habitats ...

    Authors: ShanShan Zhu, YongHui Lei, Chong Wang, YuMei Wei, ChunCheng Wang and YanFei Sun

    Citation: BMC Microbiology 2021 21:170

    Content type: Research

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  3. Campylobacter jejuni is the major micro-bacillary pathogen responsible for human coloenteritis. Lactic acid bacteria (LAB) have been shown to protect against Campylobacter infection. However, LAB with a good abil...

    Authors: Xing Jin, Yufeng He, Yonghua Zhou, Xiaohua Chen, Yuan-kun Lee, Jianxin Zhao, Hao Zhang, Wei Chen and Gang Wang

    Citation: BMC Microbiology 2021 21:169

    Content type: Research article

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  4. Significant progress has been made in advancing and standardizing tools for human genomic and biomedical research. Yet, the field of next-generation sequencing (NGS) analysis for microorganisms (including mult...

    Authors: Delphine Larivière, Laura Wickham, Kenneth Keiler and Anton Nekrutenko

    Citation: BMC Microbiology 2021 21:168

    Content type: Methodology article

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  5. Efficient high-throughput drug screening assays are necessary to enable the discovery of new anti-mycobacterial drugs. The purpose of our work was to develop and validate an assay based on live-cell imaging wh...

    Authors: Sadaf Kalsum, Blanka Andersson, Jyotirmoy Das, Thomas Schön and Maria Lerm

    Citation: BMC Microbiology 2021 21:167

    Content type: Research

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  6. Antibiotic exposure during pregnancy will adversely affect the growth of offspring; however, this remains controversial and the mechanism is poorly understood. To study this phenomenon, we added ceftriaxone so...

    Authors: Xin Yang, Ting Tang, Jing Wen, Mengchun Li, Jie Chen, Tingyu Li, Ying Dai and Qian Cheng

    Citation: BMC Microbiology 2021 21:166

    Content type: Research

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  7. Lactobacillus rhamnosus GG (LGG) is the most widely used probiotic, but the mechanisms underlying its beneficial effects remain unresolved. Previous studies typically inoculated LGG in hosts with established gut ...

    Authors: Jinhee Kim, Iyshwarya Balasubramanian, Sheila Bandyopadhyay, Ian Nadler, Rajbir Singh, Danielle Harlan, Amanda Bumber, Yuling He, Lee J. Kerkhof, Nan Gao, Xiaoyang Su and Ronaldo P. Ferraris

    Citation: BMC Microbiology 2021 21:165

    Content type: Research article

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  8. The rate of fluoroquinolone (FQ) resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) is high. The present study aimed to investigate the distribution of fluoroquinolone resistance determinants in c...

    Authors: Qing Zhan, Yanlei Xu, Bingjie Wang, Jingyi Yu, Xiaofei Shen, Li Liu, Xingwei Cao, Yinjuan Guo and Fangyou Yu

    Citation: BMC Microbiology 2021 21:164

    Content type: Research

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  9. The intestinal microbiota plays a crucial role in human health, adjusting its composition and the microbial metabolites protects the gut against invading microorganisms. Enteroaggregative E. coli (EAEC) is an imp...

    Authors: Tamara Renata Machado Ribeiro, Mateus Kawata Salgaço, Maria Angela Tallarico Adorno, Miriam Aparecida da Silva, Roxane Maria Fontes Piazza, Katia Sivieri and Cristiano Gallina Moreira

    Citation: BMC Microbiology 2021 21:163

    Content type: Research article

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  10. Human well-being has been linked to the composition and functional capacity of the intestinal microbiota. As regular exercise is known to improve human health, it is not surprising that exercise was previously...

    Authors: Lucas Moitinho-Silva, Michelle Wegener, Sandra May, Florian Schrinner, Awais Akhtar, Teide J. Boysen, Eva Schaeffer, Clint Hansen, Timo Schmidt, Malte C. Rühlemann, Matthias Hübenthal, Philipp Rausch, Mustafa T. Kondakci, Walter Maetzler, Stephan Weidinger, Matthias Laudes…

    Citation: BMC Microbiology 2021 21:162

    Content type: Research article

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  11. SAPHO syndrome is a group of symptoms consisting of synovitis, acne, pustulosis, hyperostosis and osteosis. There is no specific laboratory index assist in the diagnosis of SAPHO because of its highly heteroge...

    Authors: Jianhua Zhen, Yuxiu Sun, Pengfei Zhao, Chen Li, Hesong Wang, Yini Li, Lu Zhao, Li Wang, Guangrui Huang and Anlong Xu

    Citation: BMC Microbiology 2021 21:161

    Content type: Research article

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  12. Computational approaches are often used to predict regulatory RNAs in bacteria, but their success is limited to RNAs that are highly conserved across phyla, in sequence and structure. The ANTAR regulatory syst...

    Authors: Dolly Mehta and Arati Ramesh

    Citation: BMC Microbiology 2021 21:159

    Content type: Research article

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  13. New developments in next-generation sequencing technologies and massive data received from this approach open wide prospects for personalised medicine and nutrition studies. Metagenomic analysis of the gut mic...

    Authors: Jekaterina Kazantseva, Esther Malv, Aleksei Kaleda, Aili Kallastu and Anne Meikas

    Citation: BMC Microbiology 2021 21:158

    Content type: Research article

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  14. Studies have shown that drug-resistant tuberculosis (DR-TB) in South Africa (SA) is clonal and is caused mostly by transmission. Identifying transmission chains is important in controlling DR-TB. This study re...

    Authors: Halima Said, John Ratabane, Linda Erasmus, Yasmin Gardee, Shaheed Omar, Andries Dreyer, Farzana Ismail, Zaheda Bhyat, Tiisetso Lebaka, Minty van der Meulen, Thabisile Gwala, Adeboye Adelekan, Karidia Diallo and Nazir Ismail

    Citation: BMC Microbiology 2021 21:157

    Content type: Research

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  15. Colorectal cancer (CRC) is one of the most common cancers. In recent studies, the gut microbiota has been reported to be potentially involved in aggravating or favoring CRC development. However, little is know...

    Authors: Qiulin Yao, Meifang Tang, Liuhong Zeng, Zhonghua Chu, Hui Sheng, Yuyu Zhang, Yuan Zhou, Hongyun Zhang, Huayan Jiang and Mingzhi Ye

    Citation: BMC Microbiology 2021 21:156

    Content type: Research

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  16. Eucalyptus bacterial wilt caused by Ralstonia solanacearum is an important eucalyptus disease. Endophytic fungi, an important source of natural active substances, provide a new breakthrough for the control of pla...

    Authors: Ziling Mao, Weihao Zhang, Chunyin Wu, Hao Feng, Yuanhang Peng, Hamza Shahid, Zining Cui, Ping Ding and Tijiang Shan

    Citation: BMC Microbiology 2021 21:155

    Content type: Research

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  17. Bifidobacteria are commensal microbes of the mammalian gastrointestinal tract. In this study, we aimed to identify the intestinal colonization mechanisms and key metabolic pathways implemented by Bifidobacterium ...

    Authors: Melinda A. Engevik, Heather A. Danhof, Anne Hall, Kristen A. Engevik, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Bradley T. Endres, Meghna Bajaj, Kevin W. Garey, Robert A. Britton, Jennifer K. Spinler, Anthony M. Haag and James Versalovic

    Citation: BMC Microbiology 2021 21:154

    Content type: Research article

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  18. Salmonella can invade host cells via a type three secretion system called T3SS-1 and its outer membrane proteins, PagN and Rck. However, the mechanism of PagN-dependent invasion pathway used by Salmonella enteric...

    Authors: Emilie Barilleau, Mégane Védrine, Michael Koczerka, Julien Burlaud-Gaillard, Florent Kempf, Olivier Grépinet, Isabelle Virlogeux-Payant, Philippe Velge and Agnès Wiedemann

    Citation: BMC Microbiology 2021 21:153

    Content type: Research

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  19. Inter-individual variations in gut microbiota composition are observed even among healthy populations. The gut microbiota may exhibit a unique composition depending on the country of origin and race of individ...

    Authors: Jonguk Park, Kumiko Kato, Haruka Murakami, Koji Hosomi, Kumpei Tanisawa, Takashi Nakagata, Harumi Ohno, Kana Konishi, Hitoshi Kawashima, Yi-An Chen, Attayeb Mohsen, Jin-zhong Xiao, Toshitaka Odamaki, Jun Kunisawa, Kenji Mizuguchi and Motohiko Miyachi

    Citation: BMC Microbiology 2021 21:151

    Content type: Research article

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  20. The objective of this study was to evaluate the chemical compositions and microbial communities of salt-tolerant alfalfa silage. Salt-tolerant alfalfa was ensiled with no additive control, and cellulase for 30...

    Authors: Duo Wen Sa, Qiang Lu, Zhen Wang, Gentu Ge, Lin Sun and Yushan Jia

    Citation: BMC Microbiology 2021 21:149

    Content type: Research

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  21. Recurrent tonsillitis is one of the most common otolaryngological disorders caused by cell-invading bacteria, such as Streptococcus pyogenes (S. pyogenes) and Haemophilus influenzae. The aim of this study was to ...

    Authors: Hiroyuki Iuchi, Junichiro Ohori, Satoshi Kiyama, Naoko Imuta, Junichiro Nishi, Yuichi Kurono and Masaru Yamashita

    Citation: BMC Microbiology 2021 21:148

    Content type: Research

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  22. Gestational diabetes mellitus (GDM), a common endocrine disorder with rising prevalence in pregnancy, has been reported to be associated with alteration of gut microbiota in recent years. However, the role of ...

    Authors: Fang Chen, Yu Gan, Yingtao Li, Wenzhi He, Weizhen Wu, Kejian Wang and Qing Li

    Citation: BMC Microbiology 2021 21:147

    Content type: Research

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  23. Gut microbiota closely communicate in the immune system to maintain a balanced immune homeostasis in the gastrointestinal tract of the host. Oral administration of probiotics modulates gut microbiota compositi...

    Authors: Sang-Kap Han, Yeon-Jeong Shin, Dong-Yeon Lee, Kyung Min Kim, Seo-Jin Yang, Du Seong Kim, Ji-Whi Choi, Seunghun Lee and Dong-Hyun Kim

    Citation: BMC Microbiology 2021 21:146

    Content type: Research

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  24. Group B streptococci (GBS) are important neonatal bacterial pathogens that can cause severe invasive disease in the newborn. It is thought that in many cases of invasive neonatal GBS disease, the bacteria asce...

    Authors: Maram Hulbah, Matthew A. Croxen and Gregory J. Tyrrell

    Citation: BMC Microbiology 2021 21:145

    Content type: Research article

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  25. Tuberculosis (T.B) is one of the major infectious diseases in the developing countries. The diagnosis of extrapulmonary T.B (EPTB) remains problematic and emergence of resistant strains poses a significant thr...

    Authors: Asmaa Mohammed Elbrolosy, Rana H. El Helbawy, Osama M. Mansour and Reda Abdel Latif

    Citation: BMC Microbiology 2021 21:144

    Content type: Research

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  26. Seed dimorphism has been thought to be a bet-hedging strategy that helps plants survive in the disturbed environment and has been widely studied for its ecological adaptation mechanism. Many studies showed tha...

    Authors: Hongfei Wang, Manik Prabhu Narsing Rao, Yanli Gao, Xinyang Li, Rui Gao, Yuanguo Xie, Qiuli Li and Wenjun Li

    Citation: BMC Microbiology 2021 21:143

    Content type: Research

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  27. Chinese soft-shell turtle (Pelodiscus sinensis) is an important commercial species for their high nutritional value and unique taste, but it has been a vulnerable species due to habitat loss. In this study, homol...

    Authors: Benli Wu, Long Huang, Jing Chen, Ye Zhang, Jun Wang and Jixiang He

    Citation: BMC Microbiology 2021 21:142

    Content type: Research article

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  28. The potential role of the gut microbiome (GM) in heart failure (HF) had recently been revealed. However, the underlying mechanisms of the GM and fecal metabolome in HF have not been characterized. The Dahl sal...

    Authors: Lin Li, Sen-jie Zhong, Si-yuan Hu, Bin Cheng, Hong Qiu and Zhi-xi Hu

    Citation: BMC Microbiology 2021 21:141

    Content type: Research

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  29. Group B Streptococcus (GBS) infection is the leading cause of septicemia, meningitis, and pneumonia in neonates. Aberrant gut colonization in early life may predispose children to various diseases in adulthood...

    Authors: Yue-feng Li, Xue-lei Gong, Su-xiang Chen, Kejian Wang and Yan-hua Jiang

    Citation: BMC Microbiology 2021 21:140

    Content type: Research article

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  30. The information on antibiotic resistance and molecular features of Group B Streptococcus (GBS) are essential for epidemiological purposes as well as vaccine development. Therefore, we aimed to assess the antimicr...

    Authors: Tahereh Motallebirad, Hossein Fazeli, Ataollah Ghahiri, Dariush Shokri, Saba Jalalifar, Sharareh Moghim and Bahram Nasr Esfahani

    Citation: BMC Microbiology 2021 21:139

    Content type: Research

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  31. Ulcerative colitis (UC) is one of the primary types of inflammatory bowel disease (IBD), the occurrence of which has been increasing worldwide. Although IBD is an intensively studied human microbiome-associate...

    Authors: Wendy Li, Yang Sun, Lin Dai, Hongju Chen, Bin Yi, Junkun Niu, Lan Wang, Fengrui Zhang, Juan Luo, Kunhua Wang, Rui Guo, Lianwei Li, Quan Zou, Zhanshan (Sam) Ma and Yinglei Miao

    Citation: BMC Microbiology 2021 21:138

    Content type: Research

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  32. Burkholderia pseudomallei, a facultative intracellular bacterium, is the aetiological agent of melioidosis that is responsible for up to 40% sepsis-related mortality in epidemic areas. However, no effective vacci...

    Authors: Siqi Yuan, Yao Fang, Mengling Tang, Zhiqiang Hu, Chenglong Rao, Jiangao Chen, Yupei Xia, Meijuan Zhang, Jingmin Yan, Bin Tang, Xiaoyi He, Jianping Xie, Xuhu Mao and Qian Li

    Citation: BMC Microbiology 2021 21:137

    Content type: Research

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  33. Antimicrobial resistance (AMR) poses a complex threat to global health security and universal health coverage. Recently, nosocomial infections with carbapenemase-producing Gram-negative bacilli (GNB) is increa...

    Authors: Hana S. Elbadawi, Kamal M. Elhag, Elsheikh Mahgoub, Hisham N. Altayb, Francine Ntoumi, Linzy Elton, Timothy D. McHugh, John Tembo, Giuseppe Ippolito, Abdinasir Yusuf Osman, Alimuddin Zumla and Muzamil M. Abdel Hamid

    Citation: BMC Microbiology 2021 21:136

    Content type: Research article

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  34. Streptococcus pyogenes (S. pyogenes) is a Gram positive bacterium which is a leading cause of pharyngitis, skin and soft tissue infection and post streptococcal syndromes. Due to lack of β-lactamase enzyme produc...

    Authors: Destaw Kebede, Alemale Admas and Daniel Mekonnen

    Citation: BMC Microbiology 2021 21:135

    Content type: Research

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  35. Fungal spores dispersed in the atmosphere may become cause of different pathological conditions and allergies for human beings. A number of studies have been performed to analyze the diversity of airborne fung...

    Authors: Yumna Nageen, Michael Dare Asemoloye, Sergei Põlme, Xiao Wang, Shihan Xu, Pramod W. Ramteke and Lorenzo Pecoraro

    Citation: BMC Microbiology 2021 21:134

    Content type: Research

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  36. The prevalence of clinical multidrug-resistant (MDR) Pseudomonas aeruginosa has been increasing rapidly worldwide over the years and responsible for a wide range of acute and chronic infections with high mortalit...

    Authors: Mingju Hao, Wanshan Ma, Xiutao Dong, Xiaofeng Li, Fang Cheng and Yujiao Wang

    Citation: BMC Microbiology 2021 21:133

    Content type: Research

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  37. P. aeruginosa is the primary source of hospital-acquired infections. Unfortunately, antibiotic resistance is growing to precariously high levels, making the infections by this pathogen life-threatening and hard t...

    Authors: Bahareh Lashtoo Aghaee, Mohammadali Khan Mirzaei, Mohammad Yousef Alikhani and Ali Mojtahedi

    Citation: BMC Microbiology 2021 21:132

    Content type: Research

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  38. Evidence was previously provided for sex-related differences in the human gut microbiota composition, and sex-specific discrepancy in hormonal profiles was proposed as a main determinant of these differences. ...

    Authors: Alexander Koliada, Vladislav Moseiko, Mariana Romanenko, Oleh Lushchak, Nadiia Kryzhanovska, Vitaly Guryanov and Alexander Vaiserman

    Citation: BMC Microbiology 2021 21:131

    Content type: Research

    Published on:

  39. The coral microbiome plays a key role in host health by being involved in energy metabolism, nutrient cycling, and immune system formation. Inoculating coral with beneficial bacterial consortia may enhance the...

    Authors: Ying Zhang, Qingsong Yang, Juan Ling, Lijuan Long, Hui Huang, Jianping Yin, Meilin Wu, Xiaoyu Tang, Xiancheng Lin, Yanying Zhang and Junde Dong

    Citation: BMC Microbiology 2021 21:130

    Content type: Research article

    Published on:

    The Correction to this article has been published in BMC Microbiology 2021 21:150

  40. Hypertension (HTN) is one of the major cardiovascular risk factors, which contributes to increasing target organ damages and cardiovascular morbidity and mortality worldwide. Isolated systolic HTN (ISH) and is...

    Authors: Pan Wang, Ying Dong, Kun Zuo, Chunming Han, Jie Jiao, Xinchun Yang and Jing Li

    Citation: BMC Microbiology 2021 21:128

    Content type: Research

    Published on:

  41. Fungi are premier hosts for the high-yield secretion of proteins for biomedical and industrial applications. The stability and activity of these secreted proteins is often dependent on the culture pH. As yeast...

    Authors: Rianne C. Prins and Sonja Billerbeck

    Citation: BMC Microbiology 2021 21:127

    Content type: Methodology article

    Published on:

  42. Infants suffer from a severe epileptic encephalopathy known as West syndrome (WS). Treatment with adrenocorticotropic hormone (ACTH) indicates the involvement of the gut-brain axis in WS. Several pieces of evi...

    Authors: Lu Xu, Dandan Chen, Congying Zhao, Lihua Jiang, Shanshan Mao, Chao Song and Feng Gao

    Citation: BMC Microbiology 2021 21:126

    Content type: Research article

    Published on:

  43. Members of the Erysipelotrichaceae family have a high abundance in the intestinal tract of mammals, and have been reported to be associated with host metabolic disorders and inflammatory diseases. In our previ...

    Authors: Jinyuan Wu, Min Liu, Mengqing Zhou, Lin Wu, Hui Yang, Lusheng Huang and Congying Chen

    Citation: BMC Microbiology 2021 21:125

    Content type: Research

    Published on:

  44. Gram-negative bacteria (GNB) including Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae represent the most relevant reservoir of resistance genes such as metallo-β-lactamase (MBL) and AmpC gene...

    Authors: Chika Ejikeugwu, Okoro Nworie, Morteza Saki, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji, Chika Ezeador, Emmanuel Nwakaeze, Peter Eze, Eniola Oni, Chidiebere Obi, Ifeanyichukwu Iroha, Charles Esimone and Michael U. Adikwu

    Citation: BMC Microbiology 2021 21:124

    Content type: Research article

    Published on:

  45. Information on the genetic variability of drug resistant isolates of Mycobacterium tuberculosis is of paramount importance to understand transmission dynamics of disease and to improve TB control strategies. Desp...

    Authors: Ajay Vir Singh, Suman Singh, Anjali Yadav, Shweta Kushwah, Rajbala Yadav, Davuluri Kushma Sai and Devendra Singh Chauhan

    Citation: BMC Microbiology 2021 21:123

    Content type: Research article

    Published on:

  46. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhiyuan Gao, Yaya Hu, Meikun Han, Junjie Xu, Xue Wang, Lanfu Liu, Zhonghou Tang, Weijing Jiao, Rong Jin, Ming Liu, Zhengjun Guan and Zhimin Ma

    Citation: BMC Microbiology 2021 21:121

    Content type: Correction

    Published on:

    The original article was published in BMC Microbiology 2021 21:102

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