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  1. Antibiotic-resistant Staphylococcus aureus clones have emerged globally over the last few decades. Probiotics have been actively studied as an alternative to antibiotics to prevent and treat S. aureus infections,...

    Authors: Soyoun Park, Adam Classen, Hanny Maeva Gohou, Roberto Maldonado, Emily Kretschmann, Chloe Duvernay, Geun-Joong Kim and Jennifer Ronholm
    Citation: BMC Microbiology 2021 21:189
  2. Multidrug-resistant Klebsiella pneumoniae spp. (kp) are emerging agents of severe infections of the respiratory, urinary tract and wounds that can progress to fatal septicemia. The use of bacteriophages is curren...

    Authors: Simone Eckstein, Jana Stender, Sonia Mzoughi, Kilian Vogele, Jana Kühn, Daniela Friese, Christina Bugert, Susann Handrick, Mustapha Ferjani, Roman Wölfel, Andrew Millard, Mohamed Ben Moussa and Joachim J. Bugert
    Citation: BMC Microbiology 2021 21:186
  3. The emergence of antimicrobial resistance against Mycobacterium tuberculosis (M. tuberculosis) has become the major concern in global tuberculosis control due to its limited therapy options and high mortality. Ho...

    Authors: Lin Liu, Xiujuan Zhao, Xingyong Wu, Sijing Li, Biao Liu, Mamy Jayne Nelly Rajaofera, Yingfei Zeng, Sufang Dong, Zheng Bei, Hua Pei and Qianfeng Xia
    Citation: BMC Microbiology 2021 21:185
  4. To investigate the ecological effects of chemical and biological control methods on tobacco wildfire disease, a plot field experiment was conducted to compare the control efficiency and mechanisms of a chemica...

    Authors: Tianbo Liu, Yabing Gu, Zhicheng Zhou, Zhenghua Liu, Huaqun Yin, Chong Qin, Tuyong Yi and Jiemeng Tao
    Citation: BMC Microbiology 2021 21:184
  5. Lactobacilli are often recognized as beneficial partners in human microbial environments. However, lactobacilli also cause diseases in human, e.g. infective endocarditis (IE), septicaemia, rheumatic vascular d...

    Authors: Qi Tang, Yingying Hao, Lu Wang, Chao Lu, Ming Li, Zaifeng Si, Xiaoben Wu and Zhiming Lu
    Citation: BMC Microbiology 2021 21:183
  6. Excessive reactive oxygen species (ROS) can cause serious damage to the human body and may cause various chronic diseases. Studies have found that lactic acid bacteria (LAB) have antioxidant and anti-aging eff...

    Authors: Qingfeng Ge, Bo Yang, Rui Liu, Donglei Jiang, Hai Yu, Mangang Wu and Wangang Zhang
    Citation: BMC Microbiology 2021 21:182
  7. With increasing concerns about the impact of frequent antibiotic usage on the human microbiome, it is important to characterize the potential for such effects in early antibiotic drug development clinical tria...

    Authors: Andrea Nuzzo, Stephanie Van Horn, Christopher Traini, Caroline R. Perry, Etienne F. Dumont, Nicole E. Scangarella-Oman, David F. Gardiner and James R. Brown
    Citation: BMC Microbiology 2021 21:181

    The Correction to this article has been published in BMC Microbiology 2021 21:293

  8. In the last few decades, considerable attention has been paid to entomopathogenic fungi as biocontrol agents, however little is known about their mode of action and safety. This study aimed to investigate the ...

    Authors: Mandeep Kaur, Pooja Chadha, Sanehdeep Kaur and Amarjeet Kaur
    Citation: BMC Microbiology 2021 21:180
  9. Bacterial community play a key role in environmental and ecological processes in river ecosystems. Rivers are used as receiving body for treated and untreated urban wastewaters that brings high loads of sewage...

    Authors: Keqiang Shao, Xin Yao, Zhaoshi Wu, Xingyu Jiang, Yang Hu, Xiangming Tang, Qiujin Xu and Guang Gao
    Citation: BMC Microbiology 2021 21:179
  10. The genus Ophiocordyceps, which includes Ophiocordyceps sinensis, has been demonstrated to be one of the most valuable medicinal taxa. The low rate of larval infection and slow development that characterize the c...

    Authors: Chengpeng Li, Dexiang Tang, Yuanbing Wang, Qi Fan, Xiaomei Zhang, Xiaolong Cui and Hong Yu
    Citation: BMC Microbiology 2021 21:178
  11. The global rise in the incidence of non-tuberculosis mycobacterial infections is of increasing concern due their high levels of intrinsic antibiotic resistance. Although integrated viral genomes, called propha...

    Authors: Jaycee Cushman, Emma Freeman, Sarah McCallister, Anna Schumann, Keith W. Hutchison and Sally D. Molloy
    Citation: BMC Microbiology 2021 21:176
  12. Menaquinones are constituents of prokaryote cell membranes where they play important functions during electron transport. Menaquinone profiles are strongly recommended for species classification when proposing...

    Authors: Fuquan Xie, Shengxiang Pei, Xihuang Lin, Yun Tian and Gaiyun Zhang
    Citation: BMC Microbiology 2021 21:175
  13. Molecular assays are important tools for pathogen detection but need to be periodically re-evaluated with the discovery of additional genetic diversity that may cause assays to exclude target taxa or include n...

    Authors: Colin Wood, Jason Sahl, Sara Maltinsky, Briana Coyne, Benjamin Russakoff, David Panisello Yagüe, Jolene Bowers and Talima Pearson
    Citation: BMC Microbiology 2021 21:174
  14. Bacillus cereus 0–9, a Gram-positive, endospore-forming bacterium isolated from healthy wheat roots in our previous research, is considered to be an effective biocontrol strain against several soil-borne plant di...

    Authors: Qiubin Huang, Zhen Zhang, Qing Liu, Fengying Liu, Yupeng Liu, Juanmei Zhang and Gang Wang
    Citation: BMC Microbiology 2021 21:172
  15. Bacterial plasmids often carry antibiotic resistance genes and are a significant factor in the spread of antibiotic resistance. The ability to completely assemble plasmid sequences would facilitate the localiz...

    Authors: Astrid P. Heikema, Rick Jansen, Saskia D. Hiltemann, John P. Hays and Andrew P. Stubbs
    Citation: BMC Microbiology 2021 21:171
  16. The unique climatic conditions of the Xinjiang region nurture rich melon and fruit resources, the melon and fruit sugar sources provide sufficient nutrients for the survival of yeast, and the diverse habitats ...

    Authors: ShanShan Zhu, YongHui Lei, Chong Wang, YuMei Wei, ChunCheng Wang and YanFei Sun
    Citation: BMC Microbiology 2021 21:170
  17. Campylobacter jejuni is the major micro-bacillary pathogen responsible for human coloenteritis. Lactic acid bacteria (LAB) have been shown to protect against Campylobacter infection. However, LAB with a good abil...

    Authors: Xing Jin, Yufeng He, Yonghua Zhou, Xiaohua Chen, Yuan-kun Lee, Jianxin Zhao, Hao Zhang, Wei Chen and Gang Wang
    Citation: BMC Microbiology 2021 21:169
  18. Significant progress has been made in advancing and standardizing tools for human genomic and biomedical research. Yet, the field of next-generation sequencing (NGS) analysis for microorganisms (including mult...

    Authors: Delphine Larivière, Laura Wickham, Kenneth Keiler and Anton Nekrutenko
    Citation: BMC Microbiology 2021 21:168
  19. Efficient high-throughput drug screening assays are necessary to enable the discovery of new anti-mycobacterial drugs. The purpose of our work was to develop and validate an assay based on live-cell imaging wh...

    Authors: Sadaf Kalsum, Blanka Andersson, Jyotirmoy Das, Thomas Schön and Maria Lerm
    Citation: BMC Microbiology 2021 21:167
  20. Antibiotic exposure during pregnancy will adversely affect the growth of offspring; however, this remains controversial and the mechanism is poorly understood. To study this phenomenon, we added ceftriaxone so...

    Authors: Xin Yang, Ting Tang, Jing Wen, Mengchun Li, Jie Chen, Tingyu Li, Ying Dai and Qian Cheng
    Citation: BMC Microbiology 2021 21:166
  21. Lactobacillus rhamnosus GG (LGG) is the most widely used probiotic, but the mechanisms underlying its beneficial effects remain unresolved. Previous studies typically inoculated LGG in hosts with established gut ...

    Authors: Jinhee Kim, Iyshwarya Balasubramanian, Sheila Bandyopadhyay, Ian Nadler, Rajbir Singh, Danielle Harlan, Amanda Bumber, Yuling He, Lee J. Kerkhof, Nan Gao, Xiaoyang Su and Ronaldo P. Ferraris
    Citation: BMC Microbiology 2021 21:165
  22. The rate of fluoroquinolone (FQ) resistance among carbapenem-resistant Klebsiella pneumoniae (CRKP) is high. The present study aimed to investigate the distribution of fluoroquinolone resistance determinants in c...

    Authors: Qing Zhan, Yanlei Xu, Bingjie Wang, Jingyi Yu, Xiaofei Shen, Li Liu, Xingwei Cao, Yinjuan Guo and Fangyou Yu
    Citation: BMC Microbiology 2021 21:164
  23. The intestinal microbiota plays a crucial role in human health, adjusting its composition and the microbial metabolites protects the gut against invading microorganisms. Enteroaggregative E. coli (EAEC) is an imp...

    Authors: Tamara Renata Machado Ribeiro, Mateus Kawata Salgaço, Maria Angela Tallarico Adorno, Miriam Aparecida da Silva, Roxane Maria Fontes Piazza, Katia Sivieri and Cristiano Gallina Moreira
    Citation: BMC Microbiology 2021 21:163

    The Correction to this article has been published in BMC Microbiology 2021 21:233

  24. Human well-being has been linked to the composition and functional capacity of the intestinal microbiota. As regular exercise is known to improve human health, it is not surprising that exercise was previously...

    Authors: Lucas Moitinho-Silva, Michelle Wegener, Sandra May, Florian Schrinner, Awais Akhtar, Teide J. Boysen, Eva Schaeffer, Clint Hansen, Timo Schmidt, Malte C. Rühlemann, Matthias Hübenthal, Philipp Rausch, Mustafa T. Kondakci, Walter Maetzler, Stephan Weidinger, Matthias Laudes…
    Citation: BMC Microbiology 2021 21:162
  25. SAPHO syndrome is a group of symptoms consisting of synovitis, acne, pustulosis, hyperostosis and osteosis. There is no specific laboratory index assist in the diagnosis of SAPHO because of its highly heteroge...

    Authors: Jianhua Zhen, Yuxiu Sun, Pengfei Zhao, Chen Li, Hesong Wang, Yini Li, Lu Zhao, Li Wang, Guangrui Huang and Anlong Xu
    Citation: BMC Microbiology 2021 21:161
  26. Computational approaches are often used to predict regulatory RNAs in bacteria, but their success is limited to RNAs that are highly conserved across phyla, in sequence and structure. The ANTAR regulatory syst...

    Authors: Dolly Mehta and Arati Ramesh
    Citation: BMC Microbiology 2021 21:159
  27. New developments in next-generation sequencing technologies and massive data received from this approach open wide prospects for personalised medicine and nutrition studies. Metagenomic analysis of the gut mic...

    Authors: Jekaterina Kazantseva, Esther Malv, Aleksei Kaleda, Aili Kallastu and Anne Meikas
    Citation: BMC Microbiology 2021 21:158
  28. Studies have shown that drug-resistant tuberculosis (DR-TB) in South Africa (SA) is clonal and is caused mostly by transmission. Identifying transmission chains is important in controlling DR-TB. This study re...

    Authors: Halima Said, John Ratabane, Linda Erasmus, Yasmin Gardee, Shaheed Omar, Andries Dreyer, Farzana Ismail, Zaheda Bhyat, Tiisetso Lebaka, Minty van der Meulen, Thabisile Gwala, Adeboye Adelekan, Karidia Diallo and Nazir Ismail
    Citation: BMC Microbiology 2021 21:157
  29. Colorectal cancer (CRC) is one of the most common cancers. In recent studies, the gut microbiota has been reported to be potentially involved in aggravating or favoring CRC development. However, little is know...

    Authors: Qiulin Yao, Meifang Tang, Liuhong Zeng, Zhonghua Chu, Hui Sheng, Yuyu Zhang, Yuan Zhou, Hongyun Zhang, Huayan Jiang and Mingzhi Ye
    Citation: BMC Microbiology 2021 21:156
  30. Eucalyptus bacterial wilt caused by Ralstonia solanacearum is an important eucalyptus disease. Endophytic fungi, an important source of natural active substances, provide a new breakthrough for the control of pla...

    Authors: Ziling Mao, Weihao Zhang, Chunyin Wu, Hao Feng, Yuanhang Peng, Hamza Shahid, Zining Cui, Ping Ding and Tijiang Shan
    Citation: BMC Microbiology 2021 21:155
  31. Bifidobacteria are commensal microbes of the mammalian gastrointestinal tract. In this study, we aimed to identify the intestinal colonization mechanisms and key metabolic pathways implemented by Bifidobacterium ...

    Authors: Melinda A. Engevik, Heather A. Danhof, Anne Hall, Kristen A. Engevik, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Bradley T. Endres, Meghna Bajaj, Kevin W. Garey, Robert A. Britton, Jennifer K. Spinler, Anthony M. Haag and James Versalovic
    Citation: BMC Microbiology 2021 21:154
  32. Salmonella can invade host cells via a type three secretion system called T3SS-1 and its outer membrane proteins, PagN and Rck. However, the mechanism of PagN-dependent invasion pathway used by Salmonella enteric...

    Authors: Emilie Barilleau, Mégane Védrine, Michael Koczerka, Julien Burlaud-Gaillard, Florent Kempf, Olivier Grépinet, Isabelle Virlogeux-Payant, Philippe Velge and Agnès Wiedemann
    Citation: BMC Microbiology 2021 21:153
  33. Inter-individual variations in gut microbiota composition are observed even among healthy populations. The gut microbiota may exhibit a unique composition depending on the country of origin and race of individ...

    Authors: Jonguk Park, Kumiko Kato, Haruka Murakami, Koji Hosomi, Kumpei Tanisawa, Takashi Nakagata, Harumi Ohno, Kana Konishi, Hitoshi Kawashima, Yi-An Chen, Attayeb Mohsen, Jin-zhong Xiao, Toshitaka Odamaki, Jun Kunisawa, Kenji Mizuguchi and Motohiko Miyachi
    Citation: BMC Microbiology 2021 21:151
  34. The objective of this study was to evaluate the chemical compositions and microbial communities of salt-tolerant alfalfa silage. Salt-tolerant alfalfa was ensiled with no additive control, and cellulase for 30...

    Authors: Duo Wen Sa, Qiang Lu, Zhen Wang, Gentu Ge, Lin Sun and Yushan Jia
    Citation: BMC Microbiology 2021 21:149
  35. Recurrent tonsillitis is one of the most common otolaryngological disorders caused by cell-invading bacteria, such as Streptococcus pyogenes (S. pyogenes) and Haemophilus influenzae. The aim of this study was to ...

    Authors: Hiroyuki Iuchi, Junichiro Ohori, Satoshi Kiyama, Naoko Imuta, Junichiro Nishi, Yuichi Kurono and Masaru Yamashita
    Citation: BMC Microbiology 2021 21:148
  36. Gestational diabetes mellitus (GDM), a common endocrine disorder with rising prevalence in pregnancy, has been reported to be associated with alteration of gut microbiota in recent years. However, the role of ...

    Authors: Fang Chen, Yu Gan, Yingtao Li, Wenzhi He, Weizhen Wu, Kejian Wang and Qing Li
    Citation: BMC Microbiology 2021 21:147
  37. Gut microbiota closely communicate in the immune system to maintain a balanced immune homeostasis in the gastrointestinal tract of the host. Oral administration of probiotics modulates gut microbiota compositi...

    Authors: Sang-Kap Han, Yeon-Jeong Shin, Dong-Yeon Lee, Kyung Min Kim, Seo-Jin Yang, Du Seong Kim, Ji-Whi Choi, Seunghun Lee and Dong-Hyun Kim
    Citation: BMC Microbiology 2021 21:146
  38. Group B streptococci (GBS) are important neonatal bacterial pathogens that can cause severe invasive disease in the newborn. It is thought that in many cases of invasive neonatal GBS disease, the bacteria asce...

    Authors: Maram Hulbah, Matthew A. Croxen and Gregory J. Tyrrell
    Citation: BMC Microbiology 2021 21:145
  39. Tuberculosis (T.B) is one of the major infectious diseases in the developing countries. The diagnosis of extrapulmonary T.B (EPTB) remains problematic and emergence of resistant strains poses a significant thr...

    Authors: Asmaa Mohammed Elbrolosy, Rana H. El Helbawy, Osama M. Mansour and Reda Abdel Latif
    Citation: BMC Microbiology 2021 21:144
  40. Seed dimorphism has been thought to be a bet-hedging strategy that helps plants survive in the disturbed environment and has been widely studied for its ecological adaptation mechanism. Many studies showed tha...

    Authors: Hongfei Wang, Manik Prabhu Narsing Rao, Yanli Gao, Xinyang Li, Rui Gao, Yuanguo Xie, Qiuli Li and Wenjun Li
    Citation: BMC Microbiology 2021 21:143
  41. Chinese soft-shell turtle (Pelodiscus sinensis) is an important commercial species for their high nutritional value and unique taste, but it has been a vulnerable species due to habitat loss. In this study, homol...

    Authors: Benli Wu, Long Huang, Jing Chen, Ye Zhang, Jun Wang and Jixiang He
    Citation: BMC Microbiology 2021 21:142
  42. The potential role of the gut microbiome (GM) in heart failure (HF) had recently been revealed. However, the underlying mechanisms of the GM and fecal metabolome in HF have not been characterized. The Dahl sal...

    Authors: Lin Li, Sen-jie Zhong, Si-yuan Hu, Bin Cheng, Hong Qiu and Zhi-xi Hu
    Citation: BMC Microbiology 2021 21:141
  43. Group B Streptococcus (GBS) infection is the leading cause of septicemia, meningitis, and pneumonia in neonates. Aberrant gut colonization in early life may predispose children to various diseases in adulthood...

    Authors: Yue-feng Li, Xue-lei Gong, Su-xiang Chen, Kejian Wang and Yan-hua Jiang
    Citation: BMC Microbiology 2021 21:140

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