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  1. Streptococcus pneumoniae possesses large zinc metalloproteinases on its surface. To analyse the importance in virulence of three of these metalloproteinases, intranasal challenge of MF1 outbred mice was carried o...

    Authors: Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi and Marco R Oggioni

    Citation: BMC Microbiology 2003 3:14

    Content type: Research article

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  2. Mycobacterium avium subspecies avium (M. avium) is frequently encountered in the environment, but also causes infections in animals and immunocompromised patients. In contrast, Mycobacterium avium subspecies para...

    Authors: John P Bannantine, Qing Zhang, Ling-Ling Li and Vivek Kapur

    Citation: BMC Microbiology 2003 3:10

    Content type: Research article

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  3. Actin is required for the gene expression and morphogenesis of respiratory syncytial virus (RSV), a clinically important Pneumovirus of the Paramyxoviridae family. In HEp-2 cells, RSV infection also induces actin...

    Authors: Vira Bitko, Anja Oldenburg, Nicolle E Garmon and Sailen Barik

    Citation: BMC Microbiology 2003 3:9

    Content type: Research article

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  4. We report cloning and characterization of a novel Leishmania infantum protein which we termed Lepp12, and we examine its possible implication in the interference with intramacrophage signaling pathways.

    Authors: Konstantina Fragaki, Bernard Ferrua, Baharia Mograbi, Julie Waldispühl and Joanna Kubar

    Citation: BMC Microbiology 2003 3:7

    Content type: Research article

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  5. Ebola virus causes severe, often fatal hemorrhagic fever in humans. The mechanism of escape from cellular anti-viral mechanisms is not yet fully understood. The promyelocytic leukaemia (PML) associated nuclear...

    Authors: Asa Szekely Björndal, Laszlo Szekely and Fredrik Elgh

    Citation: BMC Microbiology 2003 3:6

    Content type: Research article

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  6. Staphylococcus aureus infection of normal osteoblasts induces expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

    Authors: Emily H Alexander, F Andrea Rivera, Ian Marriott, Juan Anguita, Kenneth L Bost and Michael C Hudson

    Citation: BMC Microbiology 2003 3:5

    Content type: Research article

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  7. Putrescine is the intermediate product of arginine decarboxylase pathway in Escherichia coli which can be used as an alternative nitrogen source. Transaminase and dehydrogenase enzymes seem to be implicated in th...

    Authors: Natalya N Samsonova, Sergey V Smirnov, Irina B Altman and Leonid R Ptitsyn

    Citation: BMC Microbiology 2003 3:2

    Content type: Research article

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  8. In general, chemotaxis in Rhizobium has not been well characterized. Methyl accepting chemotaxis proteins are sensory proteins important in chemotaxis of numerous bacteria, but their involvement in Rhizobium chem...

    Authors: Christopher K Yost, Kirsten T Clark, Kate L Del Bel and Michael F Hynes

    Citation: BMC Microbiology 2003 3:1

    Content type: Research article

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  9. The association of an infectious agent with chronic fatigue syndrome (CFS) has been difficult and is further complicated by the lack of a known lesion or diseased tissue. Cell-free plasma DNA could serve as a ...

    Authors: Suzanne D Vernon, Sanjay K Shukla, Jennifer Conradt, Elizabeth R Unger and William C Reeves

    Citation: BMC Microbiology 2002 2:39

    Content type: Research article

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  10. Chlamydia pneumoniae causes human respiratory diseases and has recently been associated with atherosclerosis. Analysis of the three recently published C. pneumoniae genomes has led to the identification of a new ...

    Authors: Wasna Viratyosin, Lee Ann Campbell, Cho-Chou Kuo and Daniel D Rockey

    Citation: BMC Microbiology 2002 2:38

    Content type: Research article

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  11. Currently available reference methods for the molecular epidemiology of the Mycobacterium tuberculosis complex either lack sensitivity or are still too tedious and slow for routine application. Recently, tandem r...

    Authors: Philippe Le Flèche, Michel Fabre, France Denoeud, Jean-Louis Koeck and Gilles Vergnaud

    Citation: BMC Microbiology 2002 2:37

    Content type: Research article

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  12. Chlamydiae are obligate intracellular bacteria, which are important human pathogens. Genome sequences of C. trachomatis and C. pneumoniae have revealed the presence of a Chlamydia specific gene family encoding po...

    Authors: Brian Berg Vandahl, Anna Sofie Pedersen, Kris Gevaert, Arne Holm, Joël Vandekerckhove, Gunna Christiansen and Svend Birkelund

    Citation: BMC Microbiology 2002 2:36

    Content type: Research article

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  13. In 1982 Smith and Huggins showed that bacteriophages could be at least as effective as antibiotics in preventing mortality from experimental infections with a capsulated E. coli (K1) in mice. Phages that requi...

    Authors: J J Bull, Bruce R Levin, Terry DeRouin, Nina Walker and Craig A Bloch

    Citation: BMC Microbiology 2002 2:35

    Content type: Research article

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  14. Development of sulphonamide resistance in Neisseria meningitidis has been suggested to involve horizontal DNA-transfer from a commensal Neisseria species. In this study, we isolated commensal Neisseria from throa...

    Authors: Yvonne Qvarnström and Göte Swedberg

    Citation: BMC Microbiology 2002 2:34

    Content type: Research article

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  15. Bacillus mycoides Flügge, a Gram-positive, non-motile soil bacterium assigned to Bacillus cereus group, grows on agar as chains of cells linked end to end, forming radial filaments curving clock- or counter-clock...

    Authors: Carmen Di Franco, Elena Beccari, Tiziana Santini, Giuseppe Pisaneschi and Giorgio Tecce

    Citation: BMC Microbiology 2002 2:33

    Content type: Research article

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  16. The Sec-dependent protein export apparatus of Escherichia coli is very efficient at correctly identifying proteins to be exported from the cytoplasm. Even bacterial strains that carry prl mutations, which allow e...

    Authors: Ipsita Mallik, Margaret A Smith and Ann M Flower

    Citation: BMC Microbiology 2002 2:32

    Content type: Research article

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  17. Virulence genes on Salmonella pathogenicity island 1 (SPI1) are coordinately regulated by HilA, a member of the OmpR/ToxR family of transcription factors. Although a great deal is known about the complex regulati...

    Authors: Christine R Rodriguez, Lisa M Schechter and Catherine A Lee

    Citation: BMC Microbiology 2002 2:31

    Content type: Research article

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  18. Exported proteases are commonly associated with virulence in bacterial pathogens, yet there is a paucity of information regarding their role in Mycobacterium tuberculosis. There are five genes (mycP1-5) present w...

    Authors: Joel A Dave, Nico C Gey van Pittius, Albert D Beyers, Mario RW Ehlers and Gordon D Brown

    Citation: BMC Microbiology 2002 2:30

    Content type: Research article

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  19. The high degree of sequence heterogeneity found in Hepatitis C virus (HCV) isolates, makes robust nucleic acid-based assays difficult to generate. Polymerase chain reaction based techniques, require efficient ...

    Authors: Ping Qiu, Xiao-Yan Cai, Luquan Wang, Jonathan R Greene and Bruce Malcolm

    Citation: BMC Microbiology 2002 2:29

    Content type: Methodology article

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  20. PCR amplification of bacterial 16S rRNA genes provides the most comprehensive and flexible means of sampling bacterial communities. Sequence analysis of these cloned fragments can provide a qualitative and qua...

    Authors: Elena Busti, Roberta Bordoni, Bianca Castiglioni, Paolo Monciardini, Margherita Sosio, Stefano Donadio, Clarissa Consolandi, Luigi Rossi Bernardi, Cristina Battaglia and Gianluca De Bellis

    Citation: BMC Microbiology 2002 2:27

    Content type: Methodology article

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  21. The aberrant cell-cycle progression of HIV-1-infected kidney cells plays a major role in the pathogenesis of HIV-associated nephropathy, however the mechanisms whereby HIV-1 induces infected glomerular podocyt...

    Authors: Peter J Nelson, Masaaki Sunamoto, Mohammad Husain and Irwin H Gelman

    Citation: BMC Microbiology 2002 2:26

    Content type: Research article

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  22. We have previously reported that altered culture conditions (a broth media with shaking) could induce a strain of Helicobacter pylori to assume a long spiral morphology resembling that described for Helicobacter ...

    Authors: Kathleen MB Vinette, Kathleen M Gibney, Roy Proujansky and Paul T Fawcett

    Citation: BMC Microbiology 2002 2:24

    Content type: Research article

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  23. Detecting microbial life in extraterrestrial locations is a goal of space exploration because of ecological and health concerns about possible contamination of other planets with earthly organisms, and vice ve...

    Authors: Ronald L Crawford, Andrzej Paszczynski, Qingyong Lang, Daniel P Erwin, Lisa Allenbach, Giancarlo Corti, Tony J Anderson, I Francis Cheng, Chien Wai, Bruce Barnes, Richard Wells, Touraj Assefi and Mohammad Mojarradi

    Citation: BMC Microbiology 2002 2:22

    Content type: Methodology article

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  24. The number of patients with yeast infection has increased during the last years. Also the variety of species of clinical importance has increased. Correct species identification is often important for efficien...

    Authors: Thierry De Baere, Geert Claeys, Danielle Swinne, Caroline Massonet, Gerda Verschraegen, An Muylaert and Mario Vaneechoutte

    Citation: BMC Microbiology 2002 2:21

    Content type: Methodology article

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  25. An avian papillomavirus genome has been cloned from a cutaneous exophytic papilloma from an African grey parrot (Psittacus erithacus). The nucleotide sequence, genome organization, and phylogenetic position of th...

    Authors: Ruth Tachezy, Annabel Rector, Marta Havelkova, Elke Wollants, Pierre Fiten, Ghislain Opdenakker, A Bennett Jenson, John P Sundberg and Marc Van Ranst

    Citation: BMC Microbiology 2002 2:19

    Content type: Research article

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  26. Insertion Sequence (IS) elements are mobile genetic elements widely distributed among bacteria. Their activities cause mutations, promoting genetic diversity and sometimes adaptation. Previous studies have exa...

    Authors: Dominique Schneider, Esther Duperchy, Joëlle Depeyrot, Evelyne Coursange, Richard E Lenski and Michel Blot

    Citation: BMC Microbiology 2002 2:18

    Content type: Research article

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  27. Chlamydia pneumoniae infection has been detected by serological methods, but PCR is gaining more interest. A number of different PCR assays have been developed and some are used in combination with serology for d...

    Authors: Tina Mygind, Svend Birkelund, Niels H Birkebæk, Lars Østergaard, Jørgen Skov Jensen and Gunna Christiansen

    Citation: BMC Microbiology 2002 2:17

    Content type: Research article

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  28. Since Mycobacterium avium subspecies paratuberculosis (MAP) was isolated from intestinal tissue of a human patient suffering Crohn's disease, a controversial discussion exists whether MAP have a role in the etiol...

    Authors: Sabrina Corti and Roger Stephan

    Citation: BMC Microbiology 2002 2:15

    Content type: Research article

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  29. Methods for the extraction of DNA from filamentous fungi are frequently laborious and time consuming because most of the available protocols include maceration in liquid nitrogen after the mycelium has been gr...

    Authors: Alexandre Cassago, Rodrigo Alexandre Panepucci, Ana Maria Tortella Baião and Flavio Henrique-Silva

    Citation: BMC Microbiology 2002 2:14

    Content type: Methodology article

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  30. Escherichia coli can respire anaerobically using dimethyl sulfoxide (DMSO) or trimethylamine-N-oxide (TMAO) as the terminal electron acceptor for anaerobic energy generation. Expression of the dmsABC genes that e...

    Authors: Shawn MD Bearson, Jeffrey A Albrecht and Robert P Gunsalus

    Citation: BMC Microbiology 2002 2:13

    Content type: Research article

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  31. Prompt laboratory diagnosis of Herpes simplex virus (HSV) infection facilitates patient management and possible initiation of antiviral therapy. In our laboratory, which receives various specimen types for det...

    Authors: Julie Burrows, Andreas Nitsche, Belinda Bayly, Elise Walker, Geoff Higgins and Tuckweng Kok

    Citation: BMC Microbiology 2002 2:12

    Content type: Methodology article

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  32. Herpesviruses are not only infectious agents of worldwide distribution in humans, but have also been demonstrated in various non-human primates as well. Seventy-eight gibbons were subjected to serological test...

    Authors: Kamol Sakulwira, Apiradee Theamboonlers, Phingphol Charoonrut, Parntep Ratanakorn and Yong Poovorawan

    Citation: BMC Microbiology 2002 2:11

    Content type: Research article

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  33. In Southeast Asia, dengue viruses often co-circulate with other flaviviruses such as Japanese encephalitis virus, and due to the presence of shared antigenic epitopes it is often difficult to use serological m...

    Authors: Mary Jane Cardosa, Seok Mui Wang, Magdline Sia H Sum and Phaik Hooi Tio

    Citation: BMC Microbiology 2002 2:9

    Content type: Research article

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  34. Polyamine synthesis produces methylthioadenosine, which has to be disposed of. The cell recycles it into methionine through methylthioribose (MTR). Very little was known about MTR recycling for methionine salv...

    Authors: Agnieszka Sekowska and Antoine Danchin

    Citation: BMC Microbiology 2002 2:8

    Content type: Research article

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  35. Nontypeable Haemophilus influenzae is an important cause of otitis media in children and lower respiratory tract infection in adults with chronic obstructive pulmonary disease (COPD). Several lines of evidence su...

    Authors: Timothy F Murphy and Charmaine Kirkham

    Citation: BMC Microbiology 2002 2:7

    Content type: Research article

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  36. Enterohaemorrhagic Escherichia coli (EHEC) is considered to be common cause of haemorrhagic colitis (HC), thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome (HUS) in humans. In a previous paper, ...

    Authors: Nora L Padola, Marcelo E Sanz, Paula MA Lucchesi, Jesús E Blanco, Jorge Blanco, Miguel Blanco, Analía I Etcheverría, Guillermo H Arroyo and Alberto E Parma

    Citation: BMC Microbiology 2002 2:6

    Content type: Research article

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  37. Seeds of the legume plant Lathyrus sativus, which is grown in arid and semi arid tropical regions, contain Diamino Propionic acid (DAP). DAP is a neurotoxin, which, when consumed, causes a disease called Lathy...

    Authors: KR Rupesh, PL PremKumar, Vasanth V Shiva Kumar and Seetharaman S Jayachandran

    Citation: BMC Microbiology 2002 2:5

    Content type: Research article

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  38. The development of DNA amplification for the direct detection of M. tuberculosis from clinical samples has been a major goal of clinical microbiology during the last ten years. However, the limited sensitivity of...

    Authors: Thierry De Baere, Ricardo de Mendonça, Geert Claeys, Gerda Verschraegen, Wouter Mijs, Rita Verhelst, Sylvianne Rottiers, Leen Van Simaey, Catharine De Ganck and Mario Vaneechoutte

    Citation: BMC Microbiology 2002 2:4

    Content type: Methodology article

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