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  1. Nervous tissues express various communication molecules including natriuretic peptides, i.e. Brain Natriuretic Peptide (BNP) and C-type Natriuretic Peptide (CNP). These molecules share structural similarities wit...

    Authors: Wilfried Veron, Nicole Orange, Marc GJ Feuilloley and Olivier Lesouhaitier

    Citation: BMC Microbiology 2008 8:114

    Content type: Research article

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  2. The unusual heterodimeric leishmanial DNA topoisomerase IB consists of a large subunit containing the phylogenetically conserved "core" domain, and a small subunit harboring the C-terminal region with the char...

    Authors: Rafael Balaña-Fouce, Carlos García-Estrada, Yolanda Pérez-Pertejo and Rosa M Reguera

    Citation: BMC Microbiology 2008 8:113

    Content type: Research article

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  3. Human papillomavirus (HPV) tests are crucial diagnostic tools for the prevention of neoplastic lesions of the uterine cervix. However most commercial methods are designed to detect high-risk (HR) HPV types and...

    Authors: Stefano Menzo, Andrea Ciavattini, Patrizia Bagnarelli, Katia Marinelli, Stefano Sisti and Massimo Clementi

    Citation: BMC Microbiology 2008 8:112

    Content type: Research article

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  4. Vibrio parahaemolyticus is abundant in the aquatic environment particularly in warmer waters and is the leading cause of seafood borne gastroenteritis worldwide. Prior to 1995, numerous V. parahaemolyticus serogr...

    Authors: E Fidelma Boyd, Ana Luisa V Cohen, Lynn M Naughton, David W Ussery, Tim T Binnewies, O Colin Stine and Michelle A Parent

    Citation: BMC Microbiology 2008 8:110

    Content type: Research article

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  5. Pseudomonas aeruginosa is one of the most relevant human opportunistic bacterial pathogens. Two strains (PAO1 and PA14) have been mainly used as models for studying virulence of P. aeruginosa. The strain PA14 is ...

    Authors: Sergio Carilla-Latorre, Javier Calvo-Garrido, Gareth Bloomfield, Jason Skelton, Robert R Kay, Alasdair Ivens, José L Martinez and Ricardo Escalante

    Citation: BMC Microbiology 2008 8:109

    Content type: Research article

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  6. The Burkholderia cepacia complex (Bcc) is a collection of nine genotypically distinct but phenotypically similar species. They show wide ecological diversity and include species that are used for promoting plant ...

    Authors: Ben Ryall, Xiaoyun Lee, James EA Zlosnik, Saiko Hoshino and Huw D Williams

    Citation: BMC Microbiology 2008 8:108

    Content type: Research article

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  7. Campylobacter jejuni is a major cause of inflammatory diarrhoea in humans and is considered a commensal of the gastroenteric tract of the avian host. However, little is known about the interaction between C. jeju...

    Authors: Yi-Ping Li, Hanne Ingmer, Mogens Madsen and Dang D Bang

    Citation: BMC Microbiology 2008 8:107

    Content type: Research article

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  8. Cystic fibrosis (CF) is an inherited multi-system disorder characterised by chronic airway infection with pathogens such as Pseudomonas aeruginosa.

    Authors: Ian J Clifton, Louise A Fletcher, Clive B Beggs, Miles Denton and Daniel G Peckham

    Citation: BMC Microbiology 2008 8:105

    Content type: Research article

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  9. Among tuberculosis (TB) high incidence regions, Sub-Saharan Africa is particularly affected with approx. 1.6 million new cases every year. Besides this dramatic situation, data on the diversity of Mycobacterium t...

    Authors: Susanne Homolka, Erik Post, Barbara Oberhauser, Abu Garawani George, Lars Westman, Foday Dafae, Sabine Rüsch-Gerdes and Stefan Niemann

    Citation: BMC Microbiology 2008 8:103

    Content type: Research article

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  10. Information regarding the Alkali-Tolerance Response (AlTR) in Listeria monocytogenes is very limited. Treatment of alkali-adapted cells with the protein synthesis inhibitor chloramphenicol has revealed that the A...

    Authors: Efstathios S Giotis, Arunachalam Muthaiyan, Ian S Blair, Brian J Wilkinson and David A McDowell

    Citation: BMC Microbiology 2008 8:102

    Content type: Research article

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  11. Little is known about bacterial transcriptional regulatory networks (TRNs). In Escherichia coli, which is the organism with the largest wet-lab validated TRN, its set of interactions involves only ~50% of the rep...

    Authors: Diogo FT Veiga, Fábio FR Vicente, Marisa F Nicolás and Ana Tereza R Vasconcelos

    Citation: BMC Microbiology 2008 8:101

    Content type: Research article

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  12. The ability of an intracellular pathogen to establish infection depends on the capacity of the organism to survive and replicate inside the host. Mycobacterium fortuitum is a bacteria that contains genes involved...

    Authors: María Carmen Núñez, María Carmen Menéndez, María José Rebollo and María J García

    Citation: BMC Microbiology 2008 8:100

    Content type: Research article

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  13. Xanthomonas oryzae pv. oryzae (Xoo) and X. oryzae pv. oryzicola (Xoc) are bacterial pathogens of the worldwide staple and grass model, rice. Xoo and Xoc are closely related but Xoo invades rice vascular tissue to...

    Authors: Young-Su Seo, Malinee Sriariyanun, Li Wang, Janice Pfeiff, Jirapa Phetsom, Ye Lin, Ki-Hong Jung, Hui Hsien Chou, Adam Bogdanove and Pamela Ronald

    Citation: BMC Microbiology 2008 8:99

    Content type: Research article

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  14. In many bacteria, the signal molecule AI-2 is generated from its precursor S-ribosyl-L-homocysteine in a reaction catalysed by the enzyme LuxS. However, generation of AI-2-like activity has also been reported for...

    Authors: Timothy J Tavender, Nigel M Halliday, Kim R Hardie and Klaus Winzer

    Citation: BMC Microbiology 2008 8:98

    Content type: Research article

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  15. Invasive aspergillosis, which is mainly caused by the fungus Aspergillus fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by inhalation of airborne conidia, which are first enco...

    Authors: Françoise Botterel, Karine Gross, Oumaïma Ibrahim-Granet, Khaled Khoufache, Virginie Escabasse, André Coste, Catherine Cordonnier, Estelle Escudier and Stéphane Bretagne

    Citation: BMC Microbiology 2008 8:97

    Content type: Research article

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  16. The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to ...

    Authors: Ian R Monk, Pat G Casey, Michael Cronin, Cormac GM Gahan and Colin Hill

    Citation: BMC Microbiology 2008 8:96

    Content type: Methodology article

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  17. Arsenic (As) is a natural metalloid, widely used in anthropogenic activities, that can exist in different oxidation states. Throughout the world, there are several environments contaminated with high amounts o...

    Authors: Rita Branco, Ana-Paula Chung and Paula V Morais

    Citation: BMC Microbiology 2008 8:95

    Content type: Research article

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  18. Vibrio cholerae is widely acknowledged as one of the most important waterborne pathogen causing gastrointestinal disorders. Cholera toxin (CT) is a major virulence determinant of V. cholerae. Detection of CT-prod...

    Authors: Wataru Yamazaki, Kazuko Seto, Masumi Taguchi, Masanori Ishibashi and Kiyoshi Inoue

    Citation: BMC Microbiology 2008 8:94

    Content type: Methodology article

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  19. Diagnosis of Mycoplasma pneumoniae (MP) infection is traditionally based on serology, which may require more than two weeks for diagnostic antibodies to develop. PCR-based methods offer earlier diagnosis. During ...

    Authors: Anna C Nilsson, Per Björkman and Kenneth Persson

    Citation: BMC Microbiology 2008 8:93

    Content type: Research article

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  20. In Pseudomonas fluorescens ST, the promoter of the styrene catabolic operon, PstyA, is induced by styrene and is subject to catabolite repression. PstyA regulation relies on the StyS/StyR two-component system and...

    Authors: Giordano Rampioni, Livia Leoni, Biancamaria Pietrangeli and Elisabetta Zennaro

    Citation: BMC Microbiology 2008 8:92

    Content type: Research article

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  21. Pathogenic mycobacteria such as M. tuberculosis, M. bovis or M. leprae are characterised by their extremely slow growth rate which plays an important role in mycobacterial virulence and eradication of the bacteri...

    Authors: Astrid Lewin, Daniela Baus, Elisabeth Kamal, Fabienne Bon, Ralph Kunisch, Sven Maurischat, Michaela Adonopoulou and Katharina Eich

    Citation: BMC Microbiology 2008 8:91

    Content type: Research article

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  22. C. trachomatis organisms carry a cryptic plasmid that encodes 8 open reading frames designated as pORF1 to 8. It is not clear whether all 8 pORFs are expressed during C. trachomatis infection in humans and inform...

    Authors: Zhongyu Li, Youmin Zhong, Lei Lei, Yimou Wu, Shiping Wang and Guangming Zhong

    Citation: BMC Microbiology 2008 8:90

    Content type: Research article

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  23. Salmonella enterica serovar Heidelberg ranks amongst the most prevalent causes of human salmonellosis in Canada and an increase in resistance to extended spectrum cephalosporins (ESC) has been observed by the Can...

    Authors: Ashleigh K Andrysiak, Adam B Olson, Dobryan M Tracz, Kathryn Dore, Rebecca Irwin, Lai-King Ng and Matthew W Gilmour

    Citation: BMC Microbiology 2008 8:89

    Content type: Research article

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  24. Thermococcus litoralis is a heterotrophic facultative sulfur dependent hyperthermophilic Archaeon, which was isolated from a shallow submarine thermal spring. It has been successfully used in a two-stage fermenta...

    Authors: Mária Takács, András Tóth, Balázs Bogos, András Varga, Gábor Rákhely and Kornél L Kovács

    Citation: BMC Microbiology 2008 8:88

    Content type: Research article

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  25. Outer membrane vesicles (OMVs) are released from the outer membrane of many Gram-negative bacteria. These extracellular compartments are known to transport compounds involved in cell-cell signalling as well as...

    Authors: Vishaldeep K Sidhu, Frank-Jörg Vorhölter, Karsten Niehaus and Steven A Watt

    Citation: BMC Microbiology 2008 8:87

    Content type: Research article

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  26. Brucellosis, caused by members of the genus Brucella, remains one of the world's major zoonotic diseases. Six species have classically been recognised within the family Brucella largely based on a combination of ...

    Authors: Krishna K Gopaul, Mark S Koylass, Catherine J Smith and Adrian M Whatmore

    Citation: BMC Microbiology 2008 8:86

    Content type: Research article

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  27. Modification of teichoic acids with D-alanine by the products of the dlt operon protects Gram-positive bacteria against major antimicrobial host defense molecules such as defensins, cathelicidins, myeloperoxidase...

    Authors: Dirk Kraus, Silvia Herbert, Sascha A Kristian, Arya Khosravi, Victor Nizet, Friedrich Götz and Andreas Peschel

    Citation: BMC Microbiology 2008 8:85

    Content type: Research article

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  28. Salmonella enterica subsp. enterica serotype Enteritidis is known as an important and pathogenic clonal group which continues to cause worldwide sporadic cases and outbreaks in humans. Here a new multiple-locus v...

    Authors: Burkhard Malorny, Ernst Junker and Reiner Helmuth

    Citation: BMC Microbiology 2008 8:84

    Content type: Methodology article

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  29. Among surface antigens of nontypeable Haemophilus influenzae (NTHi), the HMW1 and HMW2 proteins are the major adhesins promoting colonization of the upper respiratory tract. Since they are potential vaccine candi...

    Authors: Maria Giufrè, Alessandra Carattoli, Rita Cardines, Paola Mastrantonio and Marina Cerquetti

    Citation: BMC Microbiology 2008 8:83

    Content type: Research article

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  30. Decorin-binding proteins (Dbps) A and B of Borrelia burgdorferi, the agent of Lyme disease, are surface-exposed lipoproteins that presumably bind to the extracellular matrix proteoglycan, decorin. B. burgdorferi ...

    Authors: Jon S Blevins, Kayla E Hagman and Michael V Norgard

    Citation: BMC Microbiology 2008 8:82

    Content type: Research article

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  31. A2143G mutation of 23S rRNA gene of H. pylori results in clarithromycin (CLR) resistance. To investigate the prevalence of the CLR resistance-related A2143G mutation of the H. pylori-specific 23S rRNA gene in Chi...

    Authors: Zhuoqi Liu, Jing Shen, Lian Zhang, Lin Shen, Qiang Li, Baozhen Zhang, Jing Zhou, Liankun Gu, Guoshuang Feng, Junling Ma, Wei-Cheng You and Dajun Deng

    Citation: BMC Microbiology 2008 8:81

    Content type: Research article

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  32. The incidence and diversity of human methanogens are insufficiently characterised in the gastrointestinal tract of both health and disease. A PCR and clone library methodology targeting the mcrA gene was adopted ...

    Authors: Pauline D Scanlan, Fergus Shanahan and Julian R Marchesi

    Citation: BMC Microbiology 2008 8:79

    Content type: Research article

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  33. Coxiella burnetii is the causative agent of Q-fever, a widespread zoonosis. Due to its high environmental stability and infectivity it is regarded as a category B biological weapon agent. In domestic animals infe...

    Authors: Marcus Panning, Jochen Kilwinski, Susanne Greiner-Fischer, Martin Peters, Stefanie Kramme, Dimitrios Frangoulidis, Hermann Meyer, Klaus Henning and Christian Drosten

    Citation: BMC Microbiology 2008 8:77

    Content type: Methodology article

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  34. Syphilis spirochete Treponema pallidum ssp. pallidum remains the enigmatic pathogen, since no virulence factors have been identified and the pathogenesis of the disease is poorly understood. Increasing rates of n...

    Authors: Petra Matějková, Michal Strouhal, David Šmajs, Steven J Norris, Timothy Palzkill, Joseph F Petrosino, Erica Sodergren, Jason E Norton, Jaz Singh, Todd A Richmond, Michael N Molla, Thomas J Albert and George M Weinstock

    Citation: BMC Microbiology 2008 8:76

    Content type: Research article

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  35. The histone-like Hlp protein is emerging as a key component in mycobacterial pathogenesis, being involved in the initial events of host colonization by interacting with laminin and glycosaminoglycans (GAGs). I...

    Authors: Michelle I Portugal, Adriane R Todeschini, Cristiana S de Lima, Carlos AM Silva, Ronaldo Mohana-Borges, Tom HM Ottenhoff, Lucia Mendonça-Previato, Jose O Previato and Maria CV Pessolani

    Citation: BMC Microbiology 2008 8:75

    Content type: Research article

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  36. Fibronectin-binding protein A (FnBPA) mediates adhesion of Staphylococcus aureus to fibronectin, fibrinogen and elastin. We previously reported that S. aureus strain P1 encodes an FnBPA protein where the fibrinog...

    Authors: Anthony Loughman, Tara Sweeney, Fiona M Keane, Giampiero Pietrocola, Pietro Speziale and Timothy J Foster

    Citation: BMC Microbiology 2008 8:74

    Content type: Research article

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  37. Campylobacter jejuni is widespread in the environment and is the major cause of bacterial gastroenteritis in humans. In the present study we use microarray-based comparative genomic hybridizations (CGH), pulsed-f...

    Authors: Sandra Rodin, Anders F Andersson, Valtteri Wirta, Lena Eriksson, Marianne Ljungström, Britta Björkholm, Hans Lindmark and Lars Engstrand

    Citation: BMC Microbiology 2008 8:73

    Content type: Research article

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  38. Diplomonads are common free-living inhabitants of anoxic aquatic environments and are also found as intestinal commensals or parasites of a wide variety of animals. Spironucleus vortens is a putatively commensal ...

    Authors: Scott C Dawson, Jonathan K Pham, Susan A House, Elizabeth E Slawson, Daniela Cronembold and W Zacheus Cande

    Citation: BMC Microbiology 2008 8:71

    Content type: Methodology article

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  39. It has been well documented over past decades that interaction of pathogens with the extracellular matrix (ECM) plays a primary role in host cell attachment and invasion. Adherence to host tissues is mediated ...

    Authors: Marina V Atzingen, Angela S Barbosa, Thales De Brito, Silvio A Vasconcellos, Zenáide M de Morais, Dirce MC Lima, Patricia AE Abreu and Ana LTO Nascimento

    Citation: BMC Microbiology 2008 8:70

    Content type: Research article

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  40. The maturation of hydrogenases into active enzymes is a complex process and e.g. a correctly assembled active site requires the involvement of at least seven proteins, encoded by hypABCDEF and a hydrogenase speci...

    Authors: Åsa Agervald, Karin Stensjö, Marie Holmqvist and Peter Lindblad

    Citation: BMC Microbiology 2008 8:69

    Content type: Research article

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  41. A fundamental characteristic of cells is the ability to divide. To date, most parameters of bacterial cultures, including cell division, have been measured as cell population averages, assuming that all bacter...

    Authors: Johanna Roostalu, Arvi Jõers, Hannes Luidalepp, Niilo Kaldalu and Tanel Tenson

    Citation: BMC Microbiology 2008 8:68

    Content type: Research article

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  42. Binding of serum components by surface M-related proteins, encoded by the emm genes, in streptococci constitutes a major virulence factor in this important group of organisms. The present study demonstrates fibri...

    Authors: Justice CF Baiano, Reiny A Tumbol, Aarti Umapathy and Andrew C Barnes

    Citation: BMC Microbiology 2008 8:67

    Content type: Research article

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  43. In 1994, an outbreak of Enterobacter sakazakii infections in France occurred in a neonatal intensive care unit during which 17 neonates were infected. More than half of the infected neonates had severe clinical s...

    Authors: Stacy Townsend, Edward Hurrell and Stephen Forsythe

    Citation: BMC Microbiology 2008 8:64

    Content type: Research article

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