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  1. The Mycoplasma hominis vaa gene encodes a highly variable, surface antigen involved in the adhesion to host cells. We have analysed the structure of the vaa locus to elucidate the genetic basis for variation of v...

    Authors: Thomas Boesen, Jeppe Emmersen, Agata Baczynska, Svend Birkelund and Gunna Christiansen

    Citation: BMC Microbiology 2004 4:37

    Content type: Research article

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  2. Streptococcus pneumoniae is the leading cause of bacterial meningitis. Pneumococcal meningitis is associated with the highest mortality among bacterial meningitis and it may also lead to neurological sequelae des...

    Authors: Damiana Chiavolini, Sergio Tripodi, Riccardo Parigi, Marco R Oggioni, Elisabetta Blasi, Marcella Cintorino, Gianni Pozzi and Susanna Ricci

    Citation: BMC Microbiology 2004 4:36

    Content type: Methodology article

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  3. Mycoplasma hominis is associated with pelvic inflammatory disease, bacterial vaginosis, post partum fever, sepsis and infections of the central nervous system often leading to serious conditions. Association with...

    Authors: Agata Baczynska, Helle F Svenstrup, Jens Fedder, Svend Birkelund and Gunna Christiansen

    Citation: BMC Microbiology 2004 4:35

    Content type: Methodology article

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  4. Infection of intestinal epithelial cells by pathogenic Salmonella leads to activation of signaling cascades that ultimately initiate the proinflammatory gene program. The transcription factor NF-κB is a key regul...

    Authors: Thomas Tallant, Amitabha Deb, Niladri Kar, Joseph Lupica, Michael J de Veer and Joseph A DiDonato

    Citation: BMC Microbiology 2004 4:33

    Content type: Research article

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  5. Gram-negative bacteria cause most nosocomial respiratory infections. At the University of Cumhuriyet, we examined 328 respiratory isolates of Enterobacteriaceae and Acinetobacter baumanii organisms in Sivas, Turk...

    Authors: Ugur Gonlugur, Mustafa Zahir Bakici, Ibrahim Akkurt and Tanseli Efeoglu

    Citation: BMC Microbiology 2004 4:32

    Content type: Research article

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  6. The fliC and fljB genes in Salmonella code for the phase 1 (H1) and phase 2 (H2) flagellin respectively, the rfb cluster encodes the majority of enzymes for polysaccharide (O) antigen biosynthesis, together they ...

    Authors: Chloe KB Mortimer, Tansy M Peters, Saheer E Gharbia, Julie MJ Logan and Catherine Arnold

    Citation: BMC Microbiology 2004 4:31

    Content type: Research article

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  7. Certain strains of an obligate parasite of the human upper respiratory tract, nontypeable Haemophilus influenzae (NTHi), can cause invasive diseases such as septicemia and meningitis, as well as chronic mucosal i...

    Authors: Dayle A Daines, Justin Jarisch and Arnold L Smith

    Citation: BMC Microbiology 2004 4:30

    Content type: Research article

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  8. Virus-like particles (VLPs) formed by the human papillomavirus (HPV) L1 capsid protein are currently being tested in clinical trials as prophylactic vaccines against genital warts and cervical cancer. The effi...

    Authors: Vanessa A Olcese, Yan Chen, Richard Schlegel and Hang Yuan

    Citation: BMC Microbiology 2004 4:29

    Content type: Research article

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  9. Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection, claiming millions of lives annually. The virus infects various cells of the respiratory tract as well as resident inflam...

    Authors: Vira Bitko, Nicolle E Garmon, Tin Cao, Benjamin Estrada, John E Oakes, Robert N Lausch and Sailen Barik

    Citation: BMC Microbiology 2004 4:28

    Content type: Research article

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  10. Pathogenic Yersinia species (Y. enterocolitica, Y. pestis, Y. pseudotuberculosis) share a t ype t hree s ecretion s ystem (TTSS) which allows translocation of effector proteins (called Yops) into host cells. It i...

    Authors: Gottfried Wilharm, Verena Lehmann, Wibke Neumayer, Janja Trček and Jürgen Heesemann

    Citation: BMC Microbiology 2004 4:27

    Content type: Research article

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  11. Cell to cell signaling systems in Gram-negative bacteria rely on small diffusible molecules such as the N-acylhomoserine lactones (AHL). These compounds are involved in the production of antibiotics, exoenzymes, ...

    Authors: Daniel Martinelli, Gilles Grossmann, Urs Séquin, Helmut Brandl and Reinhard Bachofen

    Citation: BMC Microbiology 2004 4:25

    Content type: Research article

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  12. The limited circulation of many of the agents that are likely to be used in a bioterrorism attack precludes the ready availability of positive controls. This means that only specialized laboratories can screen...

    Authors: Remy N Charrel, Bernard La Scola and Didier Raoult

    Citation: BMC Microbiology 2004 4:21

    Content type: Research article

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  13. The phylogeny of the genus Methanobrevibacter was established almost 25 years ago on the basis of the similarities of the 16S rRNA oligonucleotide catalogs. Since then, many 16S rRNA gene sequences of newly isola...

    Authors: Abhijit S Dighe, Kamlesh Jangid, José M González, Vyankatesh J Pidiyar, Milind S Patole, Dilip R Ranade and Yogesh S Shouche

    Citation: BMC Microbiology 2004 4:20

    Content type: Research article

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  14. Salmonella enterica and Campylobacter jejuni are amongst the more prevalent bacterial pathogens that cause foodborne diseases. These microorganisms are common contaminants of poultry and poultry products. This st...

    Authors: Gustavo Faúndez, Miriam Troncoso, Paola Navarrete and Guillermo Figueroa

    Citation: BMC Microbiology 2004 4:19

    Content type: Research article

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  15. Shigella is the etiological agent of shigellosis, a disease responsible for more than 500,000 deaths of children per year, in developing countries. These pathogens colonize the intestinal colon, invade, spreading...

    Authors: Emerson da Motta Willer, Renato de Lourenço Lima and Loreny Gimenes Giugliano

    Citation: BMC Microbiology 2004 4:18

    Content type: Research article

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  16. The Rio Grande River is the natural boundary between U.S. and Mexico from El Paso, TX to Brownsville, TX. and is one of the major water resources of the area. Agriculture, farming, maquiladora industry, domestic ...

    Authors: Jose Mendoza, James Botsford, Jose Hernandez, Anna Montoya, Roswitha Saenz, Adrian Valles, Alejandro Vazquez and Maria Alvarez

    Citation: BMC Microbiology 2004 4:17

    Content type: Research article

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  17. The pathogenesis of bacterial vaginosis remains largely elusive, although some microorganisms, including Gardnerella vaginalis, are suspected of playing a role in the etiology of this disorder. Recently culture-i...

    Authors: Rita Verhelst, Hans Verstraelen, Geert Claeys, Gerda Verschraegen, Joris Delanghe, Leen Van Simaey, Catharine De Ganck, Marleen Temmerman and Mario Vaneechoutte

    Citation: BMC Microbiology 2004 4:16

    Content type: Research article

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  18. The Bacillus subtilis glucokinase operon was predicted to be comprised of the genes, yqgP (now named gluP), yqgQ, and glcK. We have previously established a role for glcK in glucose metabolism. In the absence of ...

    Authors: Lili R Mesak, Felix M Mesak and Michael K Dahl

    Citation: BMC Microbiology 2004 4:13

    Content type: Research article

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  19. We describe a novel application of microarray technology for comparative genomics of bacteria in which libraries of entire genomes rather than the sequence of a single genome or sets of genes are arrayed on th...

    Authors: Lixin Zhang, Usha Srinivasan, Carl F Marrs, Debashis Ghosh, Janet R Gilsdorf and Betsy Foxman

    Citation: BMC Microbiology 2004 4:12

    Content type: Methodology article

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  20. Prodigiosin produced by Serratia marcescens is a promising drug owing to its reported characteristics of having antifungal, immunosuppressive and antiproliferative activity. From an industrial point of view the n...

    Authors: Anuradha V Giri, Nandini Anandkumar, Geetha Muthukumaran and Gautam Pennathur

    Citation: BMC Microbiology 2004 4:11

    Content type: Research article

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  21. Enteropathogenic Escherichia coli (EPEC), mainly causing infantile diarrhoea, represents one of at least six different categories of diarrheagenic E. coli with corresponding distinct pathogenic schemes. The mecha...

    Authors: Roger Stephan, Nicole Borel, Claudio Zweifel, Miguel Blanco and Jesús E Blanco

    Citation: BMC Microbiology 2004 4:10

    Content type: Research article

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  22. The thiomethyl group of S-adenosylmethionine is often recycled as methionine from methylthioadenosine. The corresponding pathway has been unravelled in Bacillus subtilis. However methylthioadenosine is subjected ...

    Authors: Agnieszka Sekowska, Valérie Dénervaud, Hiroki Ashida, Karine Michoud, Dieter Haas, Akiho Yokota and Antoine Danchin

    Citation: BMC Microbiology 2004 4:9

    Content type: Research article

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  23. Chlamydia trachomatis is a prevalent sexually transmitted disease and the leading cause of infectious blindness in developing nations. It was not known if C. trachomatis-infection influenced metabolism of lipopro...

    Authors: Grant M Hatch and Grant McClarty

    Citation: BMC Microbiology 2004 4:8

    Content type: Research article

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  24. Serology is often used for the diagnosis of Mycoplasma pneumoniae. It is important to identify specific antigens that can distinguish between the presence or absence of antibodies against M. pneumoniae. The two p...

    Authors: Mette Drasbek, Pernille K Nielsen, Kenneth Persson, Svend Birkelund and Gunna Christiansen

    Citation: BMC Microbiology 2004 4:7

    Content type: Research article

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  25. Bacillus subtilis glucokinase (GlcK) (GenBank NP_390365) is an ATP-dependent kinase that phosphorylates glucose to glucose 6-phosphate. The GlcK protein has very low sequence identity (13.7%) to the Escherichia c...

    Authors: Lili R Mesak, Felix M Mesak and Michael K Dahl

    Citation: BMC Microbiology 2004 4:6

    Content type: Research article

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  26. Histology and/or culture are generally considered the gold standard for the detection of H. pylori infection. Especially in children, these tests may result in a false negative outcome because of patchy distribut...

    Authors: Kathleen MB Vinette, Kathleen M Gibney, Roy Proujansky and Paul T Fawcett

    Citation: BMC Microbiology 2004 4:5

    Content type: Research article

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  27. Sucrose density gradient centrifugation and cross-flow filtration methods have been developed and standardised for the safe and reproducible production of inactivated arbovirus antigens which are appropriate f...

    Authors: Alyssa T Pyke, Debra A Phillips, Teck F Chuan and Greg A Smith

    Citation: BMC Microbiology 2004 4:3

    Content type: Research article

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  28. Deinococcus radiodurans R1 is one of the most radiation-resistant organisms known and is able to repair an unusually large amount of DNA damage without induced mutation. Single-stranded DNA-binding (SSB) protein ...

    Authors: Julie Malia Eggington, Nami Haruta, Elizabeth Anne Wood and Michael Matthew Cox

    Citation: BMC Microbiology 2004 4:2

    Content type: Research article

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  29. Anaplasma phagocytophilum strains often vary in Msp2 expression, a situation assumed to be related to immune evasion. However, Msp2 is also an adhesin, and little is known about the role of endogenous msp2 transc...

    Authors: Diana G Scorpio, Karen Caspersen, Hiroyuki Ogata, Jinho Park and J Stephen Dumler

    Citation: BMC Microbiology 2004 4:1

    Content type: Research article

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  30. Viral replication as well as an immunopathological component are assumed to be involved in the development of coxsackie B virus (CBV)-induced myocarditis. We observed that mycophenolic acid (MPA), the active m...

    Authors: Elizaveta Padalko, Erik Verbeken, Patrick Matthys, Joeri L Aerts, Erik De Clercq and Johan Neyts

    Citation: BMC Microbiology 2003 3:25

    Content type: Research article

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  31. The transition metal molybdenum is essential for life. Escherichia coli imports this metal into the cell in the form of molybdate ions, which are taken up via an ABC transport system. In E. coli and other Proteob...

    Authors: David J Studholme and Richard N Pau

    Citation: BMC Microbiology 2003 3:24

    Content type: Research article

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  32. Tandem repeats contained within coding regions can mediate phase variation when the repeated units change the reading frame of the coding sequence in a copy number dependent manner. Coding tandem repeats are t...

    Authors: Philip Jordan, Lori AS Snyder and Nigel J Saunders

    Citation: BMC Microbiology 2003 3:23

    Content type: Research article

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  33. Bacterial mercury resistance is based on enzymatic reduction of ionic mercury to elemental mercury and has recently been demonstrated to be applicable for industrial wastewater clean-up. The long-term monitori...

    Authors: Andreas DM Felske, Wanda Fehr, Björg V Pauling, Harald von Canstein and Irene Wagner-Döbler

    Citation: BMC Microbiology 2003 3:22

    Content type: Research article

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  34. Pseudomonas aeruginosa, an increasingly prevalent opportunistic pathogen, utilizes a type III secretion system for injection of toxins into host cells in order to initiate infection. A crucial component of this s...

    Authors: Max Nanao, Sylvie Ricard-Blum, Anne Marie Di Guilmi, David Lemaire, David Lascoux, Jacqueline Chabert, Ina Attree and Andréa Dessen

    Citation: BMC Microbiology 2003 3:21

    Content type: Research article

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  35. To date PCR detection of Chlamydia pneumoniae DNA in atherosclerotic lesions from Danish patients has been unsuccessful. To establish whether non-detection was caused by a suboptimal DNA extraction method, we tes...

    Authors: Tina Mygind, Lars Østergaard, Svend Birkelund, Jes S Lindholt and Gunna Christiansen

    Citation: BMC Microbiology 2003 3:19

    Content type: Research article

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  36. Bacterial macrofibers twist as they grow, writhe, supercoil and wind up into plectonemic structures (helical forms the individual filaments of which cannot be taken apart without unwinding) that eventually car...

    Authors: Neil H Mendelson, Patrick Shipman, Darshan Roy, Liling Chen and John J Thwaites

    Citation: BMC Microbiology 2003 3:18

    Content type: Research article

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  37. In spite of Argentina having one of the highest frequencies of haemolytic uraemic syndrome (HUS), the incidence of Escherichia coli O157:H7 is low in comparison to rates registered in the US. Isolation of several...

    Authors: Pablo M Molina, Alberto E Parma and Marcelo E Sanz

    Citation: BMC Microbiology 2003 3:17

    Content type: Research article

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  38. It is well known that expression of certain bacterial genes responds rapidly to such stimuli as exposure to toxic chemicals and physical agents. It is generally believed that the proteins encoded in these gene...

    Authors: Yuko Yamaguchi, Toshifumi Tomoyasu, Akiko Takaya, Mizue Morioka and Tomoko Yamamoto

    Citation: BMC Microbiology 2003 3:16

    Content type: Research article

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  39. Currently, there are very few tools available for subtyping Brucella isolates for epidemiological trace-back. Subtyping is difficult because of the genetic homogeneity within the genus. Sequencing of the genomes ...

    Authors: Betsy J Bricker, Darla R Ewalt and Shirley M Halling

    Citation: BMC Microbiology 2003 3:15

    Content type: Research article

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  40. Streptococcus pneumoniae possesses large zinc metalloproteinases on its surface. To analyse the importance in virulence of three of these metalloproteinases, intranasal challenge of MF1 outbred mice was carried o...

    Authors: Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi and Marco R Oggioni

    Citation: BMC Microbiology 2003 3:14

    Content type: Research article

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