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  1. SAPHO syndrome is a group of symptoms consisting of synovitis, acne, pustulosis, hyperostosis and osteosis. There is no specific laboratory index assist in the diagnosis of SAPHO because of its highly heteroge...

    Authors: Jianhua Zhen, Yuxiu Sun, Pengfei Zhao, Chen Li, Hesong Wang, Yini Li, Lu Zhao, Li Wang, Guangrui Huang and Anlong Xu
    Citation: BMC Microbiology 2021 21:161
  2. Computational approaches are often used to predict regulatory RNAs in bacteria, but their success is limited to RNAs that are highly conserved across phyla, in sequence and structure. The ANTAR regulatory syst...

    Authors: Dolly Mehta and Arati Ramesh
    Citation: BMC Microbiology 2021 21:159
  3. New developments in next-generation sequencing technologies and massive data received from this approach open wide prospects for personalised medicine and nutrition studies. Metagenomic analysis of the gut mic...

    Authors: Jekaterina Kazantseva, Esther Malv, Aleksei Kaleda, Aili Kallastu and Anne Meikas
    Citation: BMC Microbiology 2021 21:158
  4. Studies have shown that drug-resistant tuberculosis (DR-TB) in South Africa (SA) is clonal and is caused mostly by transmission. Identifying transmission chains is important in controlling DR-TB. This study re...

    Authors: Halima Said, John Ratabane, Linda Erasmus, Yasmin Gardee, Shaheed Omar, Andries Dreyer, Farzana Ismail, Zaheda Bhyat, Tiisetso Lebaka, Minty van der Meulen, Thabisile Gwala, Adeboye Adelekan, Karidia Diallo and Nazir Ismail
    Citation: BMC Microbiology 2021 21:157
  5. Colorectal cancer (CRC) is one of the most common cancers. In recent studies, the gut microbiota has been reported to be potentially involved in aggravating or favoring CRC development. However, little is know...

    Authors: Qiulin Yao, Meifang Tang, Liuhong Zeng, Zhonghua Chu, Hui Sheng, Yuyu Zhang, Yuan Zhou, Hongyun Zhang, Huayan Jiang and Mingzhi Ye
    Citation: BMC Microbiology 2021 21:156
  6. Eucalyptus bacterial wilt caused by Ralstonia solanacearum is an important eucalyptus disease. Endophytic fungi, an important source of natural active substances, provide a new breakthrough for the control of pla...

    Authors: Ziling Mao, Weihao Zhang, Chunyin Wu, Hao Feng, Yuanhang Peng, Hamza Shahid, Zining Cui, Ping Ding and Tijiang Shan
    Citation: BMC Microbiology 2021 21:155
  7. Bifidobacteria are commensal microbes of the mammalian gastrointestinal tract. In this study, we aimed to identify the intestinal colonization mechanisms and key metabolic pathways implemented by Bifidobacterium ...

    Authors: Melinda A. Engevik, Heather A. Danhof, Anne Hall, Kristen A. Engevik, Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Bradley T. Endres, Meghna Bajaj, Kevin W. Garey, Robert A. Britton, Jennifer K. Spinler, Anthony M. Haag and James Versalovic
    Citation: BMC Microbiology 2021 21:154
  8. Salmonella can invade host cells via a type three secretion system called T3SS-1 and its outer membrane proteins, PagN and Rck. However, the mechanism of PagN-dependent invasion pathway used by Salmonella enteric...

    Authors: Emilie Barilleau, Mégane Védrine, Michael Koczerka, Julien Burlaud-Gaillard, Florent Kempf, Olivier Grépinet, Isabelle Virlogeux-Payant, Philippe Velge and Agnès Wiedemann
    Citation: BMC Microbiology 2021 21:153
  9. Inter-individual variations in gut microbiota composition are observed even among healthy populations. The gut microbiota may exhibit a unique composition depending on the country of origin and race of individ...

    Authors: Jonguk Park, Kumiko Kato, Haruka Murakami, Koji Hosomi, Kumpei Tanisawa, Takashi Nakagata, Harumi Ohno, Kana Konishi, Hitoshi Kawashima, Yi-An Chen, Attayeb Mohsen, Jin-zhong Xiao, Toshitaka Odamaki, Jun Kunisawa, Kenji Mizuguchi and Motohiko Miyachi
    Citation: BMC Microbiology 2021 21:151
  10. The objective of this study was to evaluate the chemical compositions and microbial communities of salt-tolerant alfalfa silage. Salt-tolerant alfalfa was ensiled with no additive control, and cellulase for 30...

    Authors: Duo Wen Sa, Qiang Lu, Zhen Wang, Gentu Ge, Lin Sun and Yushan Jia
    Citation: BMC Microbiology 2021 21:149
  11. Recurrent tonsillitis is one of the most common otolaryngological disorders caused by cell-invading bacteria, such as Streptococcus pyogenes (S. pyogenes) and Haemophilus influenzae. The aim of this study was to ...

    Authors: Hiroyuki Iuchi, Junichiro Ohori, Satoshi Kiyama, Naoko Imuta, Junichiro Nishi, Yuichi Kurono and Masaru Yamashita
    Citation: BMC Microbiology 2021 21:148
  12. Gestational diabetes mellitus (GDM), a common endocrine disorder with rising prevalence in pregnancy, has been reported to be associated with alteration of gut microbiota in recent years. However, the role of ...

    Authors: Fang Chen, Yu Gan, Yingtao Li, Wenzhi He, Weizhen Wu, Kejian Wang and Qing Li
    Citation: BMC Microbiology 2021 21:147
  13. Gut microbiota closely communicate in the immune system to maintain a balanced immune homeostasis in the gastrointestinal tract of the host. Oral administration of probiotics modulates gut microbiota compositi...

    Authors: Sang-Kap Han, Yeon-Jeong Shin, Dong-Yeon Lee, Kyung Min Kim, Seo-Jin Yang, Du Seong Kim, Ji-Whi Choi, Seunghun Lee and Dong-Hyun Kim
    Citation: BMC Microbiology 2021 21:146
  14. Group B streptococci (GBS) are important neonatal bacterial pathogens that can cause severe invasive disease in the newborn. It is thought that in many cases of invasive neonatal GBS disease, the bacteria asce...

    Authors: Maram Hulbah, Matthew A. Croxen and Gregory J. Tyrrell
    Citation: BMC Microbiology 2021 21:145
  15. Tuberculosis (T.B) is one of the major infectious diseases in the developing countries. The diagnosis of extrapulmonary T.B (EPTB) remains problematic and emergence of resistant strains poses a significant thr...

    Authors: Asmaa Mohammed Elbrolosy, Rana H. El Helbawy, Osama M. Mansour and Reda Abdel Latif
    Citation: BMC Microbiology 2021 21:144
  16. Seed dimorphism has been thought to be a bet-hedging strategy that helps plants survive in the disturbed environment and has been widely studied for its ecological adaptation mechanism. Many studies showed tha...

    Authors: Hongfei Wang, Manik Prabhu Narsing Rao, Yanli Gao, Xinyang Li, Rui Gao, Yuanguo Xie, Qiuli Li and Wenjun Li
    Citation: BMC Microbiology 2021 21:143
  17. Chinese soft-shell turtle (Pelodiscus sinensis) is an important commercial species for their high nutritional value and unique taste, but it has been a vulnerable species due to habitat loss. In this study, homol...

    Authors: Benli Wu, Long Huang, Jing Chen, Ye Zhang, Jun Wang and Jixiang He
    Citation: BMC Microbiology 2021 21:142
  18. The potential role of the gut microbiome (GM) in heart failure (HF) had recently been revealed. However, the underlying mechanisms of the GM and fecal metabolome in HF have not been characterized. The Dahl sal...

    Authors: Lin Li, Sen-jie Zhong, Si-yuan Hu, Bin Cheng, Hong Qiu and Zhi-xi Hu
    Citation: BMC Microbiology 2021 21:141
  19. Group B Streptococcus (GBS) infection is the leading cause of septicemia, meningitis, and pneumonia in neonates. Aberrant gut colonization in early life may predispose children to various diseases in adulthood...

    Authors: Yue-feng Li, Xue-lei Gong, Su-xiang Chen, Kejian Wang and Yan-hua Jiang
    Citation: BMC Microbiology 2021 21:140
  20. The information on antibiotic resistance and molecular features of Group B Streptococcus (GBS) are essential for epidemiological purposes as well as vaccine development. Therefore, we aimed to assess the antimicr...

    Authors: Tahereh Motallebirad, Hossein Fazeli, Ataollah Ghahiri, Dariush Shokri, Saba Jalalifar, Sharareh Moghim and Bahram Nasr Esfahani
    Citation: BMC Microbiology 2021 21:139
  21. Ulcerative colitis (UC) is one of the primary types of inflammatory bowel disease (IBD), the occurrence of which has been increasing worldwide. Although IBD is an intensively studied human microbiome-associate...

    Authors: Wendy Li, Yang Sun, Lin Dai, Hongju Chen, Bin Yi, Junkun Niu, Lan Wang, Fengrui Zhang, Juan Luo, Kunhua Wang, Rui Guo, Lianwei Li, Quan Zou, Zhanshan (Sam) Ma and Yinglei Miao
    Citation: BMC Microbiology 2021 21:138
  22. Burkholderia pseudomallei, a facultative intracellular bacterium, is the aetiological agent of melioidosis that is responsible for up to 40% sepsis-related mortality in epidemic areas. However, no effective vacci...

    Authors: Siqi Yuan, Yao Fang, Mengling Tang, Zhiqiang Hu, Chenglong Rao, Jiangao Chen, Yupei Xia, Meijuan Zhang, Jingmin Yan, Bin Tang, Xiaoyi He, Jianping Xie, Xuhu Mao and Qian Li
    Citation: BMC Microbiology 2021 21:137
  23. Antimicrobial resistance (AMR) poses a complex threat to global health security and universal health coverage. Recently, nosocomial infections with carbapenemase-producing Gram-negative bacilli (GNB) is increa...

    Authors: Hana S. Elbadawi, Kamal M. Elhag, Elsheikh Mahgoub, Hisham N. Altayb, Francine Ntoumi, Linzy Elton, Timothy D. McHugh, John Tembo, Giuseppe Ippolito, Abdinasir Yusuf Osman, Alimuddin Zumla and Muzamil M. Abdel Hamid
    Citation: BMC Microbiology 2021 21:136
  24. Streptococcus pyogenes (S. pyogenes) is a Gram positive bacterium which is a leading cause of pharyngitis, skin and soft tissue infection and post streptococcal syndromes. Due to lack of β-lactamase enzyme produc...

    Authors: Destaw Kebede, Alemale Admas and Daniel Mekonnen
    Citation: BMC Microbiology 2021 21:135
  25. Fungal spores dispersed in the atmosphere may become cause of different pathological conditions and allergies for human beings. A number of studies have been performed to analyze the diversity of airborne fung...

    Authors: Yumna Nageen, Michael Dare Asemoloye, Sergei Põlme, Xiao Wang, Shihan Xu, Pramod W. Ramteke and Lorenzo Pecoraro
    Citation: BMC Microbiology 2021 21:134
  26. The prevalence of clinical multidrug-resistant (MDR) Pseudomonas aeruginosa has been increasing rapidly worldwide over the years and responsible for a wide range of acute and chronic infections with high mortalit...

    Authors: Mingju Hao, Wanshan Ma, Xiutao Dong, Xiaofeng Li, Fang Cheng and Yujiao Wang
    Citation: BMC Microbiology 2021 21:133
  27. P. aeruginosa is the primary source of hospital-acquired infections. Unfortunately, antibiotic resistance is growing to precariously high levels, making the infections by this pathogen life-threatening and hard t...

    Authors: Bahareh Lashtoo Aghaee, Mohammadali Khan Mirzaei, Mohammad Yousef Alikhani and Ali Mojtahedi
    Citation: BMC Microbiology 2021 21:132
  28. Evidence was previously provided for sex-related differences in the human gut microbiota composition, and sex-specific discrepancy in hormonal profiles was proposed as a main determinant of these differences. ...

    Authors: Alexander Koliada, Vladislav Moseiko, Mariana Romanenko, Oleh Lushchak, Nadiia Kryzhanovska, Vitaly Guryanov and Alexander Vaiserman
    Citation: BMC Microbiology 2021 21:131
  29. The coral microbiome plays a key role in host health by being involved in energy metabolism, nutrient cycling, and immune system formation. Inoculating coral with beneficial bacterial consortia may enhance the...

    Authors: Ying Zhang, Qingsong Yang, Juan Ling, Lijuan Long, Hui Huang, Jianping Yin, Meilin Wu, Xiaoyu Tang, Xiancheng Lin, Yanying Zhang and Junde Dong
    Citation: BMC Microbiology 2021 21:130

    The Correction to this article has been published in BMC Microbiology 2021 21:150

  30. Hypertension (HTN) is one of the major cardiovascular risk factors, which contributes to increasing target organ damages and cardiovascular morbidity and mortality worldwide. Isolated systolic HTN (ISH) and is...

    Authors: Pan Wang, Ying Dong, Kun Zuo, Chunming Han, Jie Jiao, Xinchun Yang and Jing Li
    Citation: BMC Microbiology 2021 21:128
  31. Fungi are premier hosts for the high-yield secretion of proteins for biomedical and industrial applications. The stability and activity of these secreted proteins is often dependent on the culture pH. As yeast...

    Authors: Rianne C. Prins and Sonja Billerbeck
    Citation: BMC Microbiology 2021 21:127
  32. Infants suffer from a severe epileptic encephalopathy known as West syndrome (WS). Treatment with adrenocorticotropic hormone (ACTH) indicates the involvement of the gut-brain axis in WS. Several pieces of evi...

    Authors: Lu Xu, Dandan Chen, Congying Zhao, Lihua Jiang, Shanshan Mao, Chao Song and Feng Gao
    Citation: BMC Microbiology 2021 21:126
  33. Members of the Erysipelotrichaceae family have a high abundance in the intestinal tract of mammals, and have been reported to be associated with host metabolic disorders and inflammatory diseases. In our previ...

    Authors: Jinyuan Wu, Min Liu, Mengqing Zhou, Lin Wu, Hui Yang, Lusheng Huang and Congying Chen
    Citation: BMC Microbiology 2021 21:125
  34. Gram-negative bacteria (GNB) including Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae represent the most relevant reservoir of resistance genes such as metallo-β-lactamase (MBL) and AmpC gene...

    Authors: Chika Ejikeugwu, Okoro Nworie, Morteza Saki, Hussein O. M. Al-Dahmoshi, Noor S. K. Al-Khafaji, Chika Ezeador, Emmanuel Nwakaeze, Peter Eze, Eniola Oni, Chidiebere Obi, Ifeanyichukwu Iroha, Charles Esimone and Michael U. Adikwu
    Citation: BMC Microbiology 2021 21:124
  35. Information on the genetic variability of drug resistant isolates of Mycobacterium tuberculosis is of paramount importance to understand transmission dynamics of disease and to improve TB control strategies. Desp...

    Authors: Ajay Vir Singh, Suman Singh, Anjali Yadav, Shweta Kushwah, Rajbala Yadav, Davuluri Kushma Sai and Devendra Singh Chauhan
    Citation: BMC Microbiology 2021 21:123
  36. Oral lichen planus (OLP), a common clinical oral disease, is associated with an increased risk of malignant transformation. The mechanism underlying the pathogenesis of OLP is unknown. Oral dysbacteriosis is r...

    Authors: Shutong Li, Yangheng Zhang, Zongcheng Yang, Jingyuan Li, Ya Li, Huanjie Li, Wenjuan Li, Jihui Jia, Shaohua Ge and Yundong Sun
    Citation: BMC Microbiology 2021 21:122
  37. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Zhiyuan Gao, Yaya Hu, Meikun Han, Junjie Xu, Xue Wang, Lanfu Liu, Zhonghou Tang, Weijing Jiao, Rong Jin, Ming Liu, Zhengjun Guan and Zhimin Ma
    Citation: BMC Microbiology 2021 21:121

    The original article was published in BMC Microbiology 2021 21:102

  38. Translation is an important point of regulation in protein synthesis. However, there is a limited number of methods available to measure global translation activity in yeast. Recently, O-propargyl-puromycin (O...

    Authors: Jennifer Staudacher, Corinna Rebnegger and Brigitte Gasser
    Citation: BMC Microbiology 2021 21:120
  39. Salinization damages the health of soil systems and reduces crop yields. Responses of microbial communities to salinized soils and their functional maintenance under high salt stress are valuable scientific pr...

    Authors: Yi Qiang Li, Ying Hui Chai, Xu Sheng Wang, Li Ying Huang, Xi Ming Luo, Cheng Qiu, Qing Hai Liu and Xiang Yu Guan
    Citation: BMC Microbiology 2021 21:119
  40. Bacterial wilt caused by Ralstonia solanacearum species complex is an important soil-borne disease worldwide that affects more than 450 plant species, including peanut, leading to great yield and quality losses. ...

    Authors: Kun Chen, Lihui Wang, Hua Chen, Chong Zhang, Shanshan Wang, Panpan Chu, Shaokang Li, Huiwen Fu, Tao Sun, Menghan Liu, Qiang Yang, Huasong Zou and Weijian Zhuang
    Citation: BMC Microbiology 2021 21:118
  41. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ngwafu Nancy Ngwasiri, Norbert W. Brattig, Dieudonné Ndjonka, Eva Liebau, Archile Paguem, Dustin Leusder, Manchang Tanyi Kingsley, Albert Eisenbarth, Alfons Renz and Achukwi Mbunkah Daniel
    Citation: BMC Microbiology 2021 21:117

    The original article was published in BMC Microbiology 2021 21:5

  42. To tackle the problem of antibiotic resistance, an extensive search for novel antibiotics is one of the top research priorities. Around 60% of the antibiotics used today were obtained from the genus Streptomyces....

    Authors: Nowreen Arefa, Ashish Kumar Sarker and Md. Ajijur Rahman
    Citation: BMC Microbiology 2021 21:116
  43. Faba bean (Vicia faba L.) cultivation is highly challenged by faba bean black root rot disease (Fusarium solani) in high lands of Ethiopia. To ensure sustainable production of faba beans, searching for eco-friend...

    Authors: Alemayehu Dugassa, Tesfaye Alemu and Yitbarek Woldehawariat
    Citation: BMC Microbiology 2021 21:115
  44. Geographically separated population growth of microbes is a common phenomenon in microbial ecology. Colonies are representative of the morphological characteristics of this structured population growth. Patter...

    Authors: Heng Xue, Masaomi Kurokawa and Bei-Wen Ying
    Citation: BMC Microbiology 2021 21:114
  45. Emerging evidence implicates the gut microbiome in liver inflammation and hepatocellular carcinoma (HCC) development. We aimed to characterize the temporal evolution of gut dysbiosis, in relation to the phenot...

    Authors: J. Behary, A. E. Raposo, N. M. L. Amorim, H. Zheng, L. Gong, E. McGovern, J. Chen, K. Liu, J. Beretov, C. Theocharous, M. T. Jackson, J. Seet-Lee, G. W. McCaughan, E. M. El-Omar and A. Zekry
    Citation: BMC Microbiology 2021 21:113
  46. Streptococcus suis type 2 (SS2) is an important zoonotic pathogen. We have previously reported the structure of LuxS protein and found that the luxS gene is closely related to biofilm, virulence gene expression a...

    Authors: Jinpeng Li, Yuxin Wang, Yanbin Du, Hui Zhang, Qingying Fan, Liyun Sun, Li Yi, Shaohui Wang and Yang Wang
    Citation: BMC Microbiology 2021 21:111

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