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  1. Many microbes possess restriction-modification systems that protect them from parasitic DNA molecules. Unfortunately, the presence of a restriction-modification system in a given microbe also hampers genetic a...

    Authors: Neil Hobson, Nancy L Price, Jordan D Ward and Tracy L Raivio
    Citation: BMC Microbiology 2008 8:134
  2. A disrupted cell cycle progression of hepatocytes was reported in chronic hepatitis C virus (HCV) infection, which can contribute significantly in the associated pathogenesis. The present study aimed to furthe...

    Authors: Saira Sarfraz, Saeed Hamid, Anwar Siddiqui, Snawar Hussain, Shahid Pervez and Graeme Alexander
    Citation: BMC Microbiology 2008 8:133
  3. The aim of the study was to detect whether in experimental Salmonella enterica Typhimurium infection the probiotic Lactobacillus fermentum ME-3 in combination with fluoroquinolone therapy would eradicate S. Typhi...

    Authors: Kai Truusalu, Raik-Hiio Mikelsaar, Paul Naaber, Tõnis Karki, Tiiu Kullisaar, Mihkel Zilmer and Marika Mikelsaar
    Citation: BMC Microbiology 2008 8:132
  4. In vitro studies with cell line infection models are beginning to disclose the strategies that Neisseria meningitidis uses to survive and multiply inside the environment of the infected host cell. The goal of thi...

    Authors: Adelfia Talà, Mario De Stefano, Cecilia Bucci and Pietro Alifano
    Citation: BMC Microbiology 2008 8:131
  5. Several methods have been reported for strain typing of Mycoplasma genitalium. The value of these methods has never been comparatively assessed. The aims of this study were: 1) to identify new potential genetic m...

    Authors: Liang Ma, Stephanie Taylor, Jørgen S Jensen, Leann Myers, Rebecca Lillis and David H Martin
    Citation: BMC Microbiology 2008 8:130
  6. Staphylococcus aureus expresses several proteases, which are thought to contribute to the virulence of this bacterium. Here we focus on aureolysin, the major thermolysin-like metalloprotease. Despite the importan...

    Authors: Artur J Sabat, Benedykt Wladyka, Klaudia Kosowska-Shick, Hajo Grundmann, Jan Maarten van Dijl, Julia Kowal, Peter C Appelbaum, Adam Dubin and Waleria Hryniewicz
    Citation: BMC Microbiology 2008 8:129
  7. All aerobically grown living cells are exposed to oxidative damage by reactive oxygen species (ROS). A major damage by ROS to proteins is caused by covalent modifications of methionine residues giving methioni...

    Authors: CongHui You, Agnieszka Sekowska, Olivera Francetic, Isabelle Martin-Verstraete, YiPing Wang and Antoine Danchin
    Citation: BMC Microbiology 2008 8:128
  8. Leifsonia xyli is a xylem-inhabiting bacterial species comprised of two subspecies: L. xyli subsp. xyli (Lxx) and L. xyli subsp. cynodontis (Lxc). Lxx is the causal agent of ratoon stunting disease in sugarcane c...

    Authors: Marcelo M Zerillo, Marie-Anne Van Sluys, Luis Eduardo A Camargo and Claudia B Monteiro-Vitorello
    Citation: BMC Microbiology 2008 8:127
  9. Type 1 fimbriae are the most commonly found fimbrial appendages on the outer membrane of Salmonella enterica serotype Typhimurium. Previous investigations indicate that static broth culture favours S. Typhimurium...

    Authors: Yin-Ching Chuang, Ke-Chuan Wang, Yi-Tseng Chen, Chia-Huei Yang, Shang-Chin Men, Chia-Chun Fan, Li-Huan Chang and Kuang-Sheng Yeh
    Citation: BMC Microbiology 2008 8:126
  10. The microbiota of an animal's intestinal tract plays important roles in the animal's overall health, productivity and well-being. There is still a scarcity of information on the microbial diversity in the gut ...

    Authors: Scot E Dowd, Todd R Callaway, Randall D Wolcott, Yan Sun, Trevor McKeehan, Robert G Hagevoort and Thomas S Edrington
    Citation: BMC Microbiology 2008 8:125
  11. Mycoplasma pneumoniae is a human pathogen that is a common cause of community-acquired pneumonia. It harbours a large number of lipoprotein genes, most of which are of unknown function. Because of their location ...

    Authors: Katri M Hallamaa, Sen-Lin Tang, Nino Ficorilli and Glenn F Browning
    Citation: BMC Microbiology 2008 8:124
  12. Comparative morphological studies and environmental sequencing surveys indicate that marine benthic environments contain a diverse assortment of microorganisms that are just beginning to be explored and charac...

    Authors: Chitchai Chantangsi, Heather J Esson and Brian S Leander
    Citation: BMC Microbiology 2008 8:123
  13. Yersinia pestis is the causative agent of plague and a potential agent of bioterrorism and biowarfare. The plague biothreat and the emergence of multidrug-resistant plague underscore the need to increase our unde...

    Authors: Karen L Stirrett, Julian A Ferreras, Sebastian M Rossi, Richard L Moy, Fabio V Fonseca and Luis EN Quadri
    Citation: BMC Microbiology 2008 8:122
  14. The sequenced genomes of the Brucella spp. have two urease operons, ure-1 and ure-2, but there is evidence that only one is responsible for encoding an active urease. The present work describes the purification a...

    Authors: Araceli Contreras-Rodriguez, Jose Quiroz-Limon, Ana M Martins, Humberto Peralta, Eric Avila-Calderon, Nammalwar Sriranganathan, Stephen M Boyle and Ahide Lopez-Merino
    Citation: BMC Microbiology 2008 8:121
  15. Recent studies showed that Helicobacter pylori existed in the New World prior to the arrival of Columbus. The purpose of the present study was to detect the presence of Helicobacter pylori in pre-Columbian mummie...

    Authors: Gonzalo Castillo-Rojas, Marco A Cerbón and Yolanda López-Vidal
    Citation: BMC Microbiology 2008 8:119
  16. Dengue (DEN) is an infectious disease caused by the DEN virus (DENV), which belongs to the Flavivirus genus in the family Flaviviridae. It has a (+) sense RNA genome and is mainly transmitted to humans by the vec...

    Authors: Catalina E Gardella-Garcia, Gerardo Perez-Ramirez, Joel Navarrete-Espinosa, Alejandro Cisneros, Fabiola Jimenez-Rojas, Luis R Ramírez-Palacios, Rocio Rosado-Leon, Minerva Camacho-Nuez and Maria de L Munoz
    Citation: BMC Microbiology 2008 8:117
  17. Kexin-like proteinases are a subfamily of the subtilisin-like serine proteinases with multiple regulatory functions in eukaryotes. In the yeast Saccharomyces cerevisiae the Kex2 protein is biochemically well inve...

    Authors: Oliver Bader, Yannick Krauke and Bernhard Hube
    Citation: BMC Microbiology 2008 8:116
  18. Flavobacterium columnare is the causative agent of columnaris disease, a disease affecting many freshwater fish species. Methods for the genetic manipulation for some of the species within the Bacteroidetes, incl...

    Authors: Andrew M Staroscik, David W Hunnicutt, Kate E Archibald and David R Nelson
    Citation: BMC Microbiology 2008 8:115
  19. Nervous tissues express various communication molecules including natriuretic peptides, i.e. Brain Natriuretic Peptide (BNP) and C-type Natriuretic Peptide (CNP). These molecules share structural similarities wit...

    Authors: Wilfried Veron, Nicole Orange, Marc GJ Feuilloley and Olivier Lesouhaitier
    Citation: BMC Microbiology 2008 8:114
  20. The unusual heterodimeric leishmanial DNA topoisomerase IB consists of a large subunit containing the phylogenetically conserved "core" domain, and a small subunit harboring the C-terminal region with the char...

    Authors: Rafael Balaña-Fouce, Carlos García-Estrada, Yolanda Pérez-Pertejo and Rosa M Reguera
    Citation: BMC Microbiology 2008 8:113
  21. Human papillomavirus (HPV) tests are crucial diagnostic tools for the prevention of neoplastic lesions of the uterine cervix. However most commercial methods are designed to detect high-risk (HR) HPV types and...

    Authors: Stefano Menzo, Andrea Ciavattini, Patrizia Bagnarelli, Katia Marinelli, Stefano Sisti and Massimo Clementi
    Citation: BMC Microbiology 2008 8:112
  22. Vibrio parahaemolyticus is abundant in the aquatic environment particularly in warmer waters and is the leading cause of seafood borne gastroenteritis worldwide. Prior to 1995, numerous V. parahaemolyticus serogr...

    Authors: E Fidelma Boyd, Ana Luisa V Cohen, Lynn M Naughton, David W Ussery, Tim T Binnewies, O Colin Stine and Michelle A Parent
    Citation: BMC Microbiology 2008 8:110
  23. Pseudomonas aeruginosa is one of the most relevant human opportunistic bacterial pathogens. Two strains (PAO1 and PA14) have been mainly used as models for studying virulence of P. aeruginosa. The strain PA14 is ...

    Authors: Sergio Carilla-Latorre, Javier Calvo-Garrido, Gareth Bloomfield, Jason Skelton, Robert R Kay, Alasdair Ivens, José L Martinez and Ricardo Escalante
    Citation: BMC Microbiology 2008 8:109
  24. The Burkholderia cepacia complex (Bcc) is a collection of nine genotypically distinct but phenotypically similar species. They show wide ecological diversity and include species that are used for promoting plant ...

    Authors: Ben Ryall, Xiaoyun Lee, James EA Zlosnik, Saiko Hoshino and Huw D Williams
    Citation: BMC Microbiology 2008 8:108
  25. Campylobacter jejuni is a major cause of inflammatory diarrhoea in humans and is considered a commensal of the gastroenteric tract of the avian host. However, little is known about the interaction between C. jeju...

    Authors: Yi-Ping Li, Hanne Ingmer, Mogens Madsen and Dang D Bang
    Citation: BMC Microbiology 2008 8:107
  26. Cystic fibrosis (CF) is an inherited multi-system disorder characterised by chronic airway infection with pathogens such as Pseudomonas aeruginosa.

    Authors: Ian J Clifton, Louise A Fletcher, Clive B Beggs, Miles Denton and Daniel G Peckham
    Citation: BMC Microbiology 2008 8:105
  27. Among tuberculosis (TB) high incidence regions, Sub-Saharan Africa is particularly affected with approx. 1.6 million new cases every year. Besides this dramatic situation, data on the diversity of Mycobacterium t...

    Authors: Susanne Homolka, Erik Post, Barbara Oberhauser, Abu Garawani George, Lars Westman, Foday Dafae, Sabine Rüsch-Gerdes and Stefan Niemann
    Citation: BMC Microbiology 2008 8:103
  28. Information regarding the Alkali-Tolerance Response (AlTR) in Listeria monocytogenes is very limited. Treatment of alkali-adapted cells with the protein synthesis inhibitor chloramphenicol has revealed that the A...

    Authors: Efstathios S Giotis, Arunachalam Muthaiyan, Ian S Blair, Brian J Wilkinson and David A McDowell
    Citation: BMC Microbiology 2008 8:102
  29. Little is known about bacterial transcriptional regulatory networks (TRNs). In Escherichia coli, which is the organism with the largest wet-lab validated TRN, its set of interactions involves only ~50% of the rep...

    Authors: Diogo FT Veiga, Fábio FR Vicente, Marisa F Nicolás and Ana Tereza R Vasconcelos
    Citation: BMC Microbiology 2008 8:101
  30. The ability of an intracellular pathogen to establish infection depends on the capacity of the organism to survive and replicate inside the host. Mycobacterium fortuitum is a bacteria that contains genes involved...

    Authors: María Carmen Núñez, María Carmen Menéndez, María José Rebollo and María J García
    Citation: BMC Microbiology 2008 8:100
  31. Xanthomonas oryzae pv. oryzae (Xoo) and X. oryzae pv. oryzicola (Xoc) are bacterial pathogens of the worldwide staple and grass model, rice. Xoo and Xoc are closely related but Xoo invades rice vascular tissue to...

    Authors: Young-Su Seo, Malinee Sriariyanun, Li Wang, Janice Pfeiff, Jirapa Phetsom, Ye Lin, Ki-Hong Jung, Hui Hsien Chou, Adam Bogdanove and Pamela Ronald
    Citation: BMC Microbiology 2008 8:99
  32. In many bacteria, the signal molecule AI-2 is generated from its precursor S-ribosyl-L-homocysteine in a reaction catalysed by the enzyme LuxS. However, generation of AI-2-like activity has also been reported for...

    Authors: Timothy J Tavender, Nigel M Halliday, Kim R Hardie and Klaus Winzer
    Citation: BMC Microbiology 2008 8:98
  33. Invasive aspergillosis, which is mainly caused by the fungus Aspergillus fumigatus, is an increasing problem in immunocompromised patients. Infection occurs by inhalation of airborne conidia, which are first enco...

    Authors: Françoise Botterel, Karine Gross, Oumaïma Ibrahim-Granet, Khaled Khoufache, Virginie Escabasse, André Coste, Catherine Cordonnier, Estelle Escudier and Stéphane Bretagne
    Citation: BMC Microbiology 2008 8:97
  34. The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to ...

    Authors: Ian R Monk, Pat G Casey, Michael Cronin, Cormac GM Gahan and Colin Hill
    Citation: BMC Microbiology 2008 8:96
  35. Arsenic (As) is a natural metalloid, widely used in anthropogenic activities, that can exist in different oxidation states. Throughout the world, there are several environments contaminated with high amounts o...

    Authors: Rita Branco, Ana-Paula Chung and Paula V Morais
    Citation: BMC Microbiology 2008 8:95
  36. Vibrio cholerae is widely acknowledged as one of the most important waterborne pathogen causing gastrointestinal disorders. Cholera toxin (CT) is a major virulence determinant of V. cholerae. Detection of CT-prod...

    Authors: Wataru Yamazaki, Kazuko Seto, Masumi Taguchi, Masanori Ishibashi and Kiyoshi Inoue
    Citation: BMC Microbiology 2008 8:94
  37. Diagnosis of Mycoplasma pneumoniae (MP) infection is traditionally based on serology, which may require more than two weeks for diagnostic antibodies to develop. PCR-based methods offer earlier diagnosis. During ...

    Authors: Anna C Nilsson, Per Björkman and Kenneth Persson
    Citation: BMC Microbiology 2008 8:93
  38. In Pseudomonas fluorescens ST, the promoter of the styrene catabolic operon, PstyA, is induced by styrene and is subject to catabolite repression. PstyA regulation relies on the StyS/StyR two-component system and...

    Authors: Giordano Rampioni, Livia Leoni, Biancamaria Pietrangeli and Elisabetta Zennaro
    Citation: BMC Microbiology 2008 8:92
  39. Pathogenic mycobacteria such as M. tuberculosis, M. bovis or M. leprae are characterised by their extremely slow growth rate which plays an important role in mycobacterial virulence and eradication of the bacteri...

    Authors: Astrid Lewin, Daniela Baus, Elisabeth Kamal, Fabienne Bon, Ralph Kunisch, Sven Maurischat, Michaela Adonopoulou and Katharina Eich
    Citation: BMC Microbiology 2008 8:91
  40. C. trachomatis organisms carry a cryptic plasmid that encodes 8 open reading frames designated as pORF1 to 8. It is not clear whether all 8 pORFs are expressed during C. trachomatis infection in humans and inform...

    Authors: Zhongyu Li, Youmin Zhong, Lei Lei, Yimou Wu, Shiping Wang and Guangming Zhong
    Citation: BMC Microbiology 2008 8:90
  41. Salmonella enterica serovar Heidelberg ranks amongst the most prevalent causes of human salmonellosis in Canada and an increase in resistance to extended spectrum cephalosporins (ESC) has been observed by the Can...

    Authors: Ashleigh K Andrysiak, Adam B Olson, Dobryan M Tracz, Kathryn Dore, Rebecca Irwin, Lai-King Ng and Matthew W Gilmour
    Citation: BMC Microbiology 2008 8:89
  42. Thermococcus litoralis is a heterotrophic facultative sulfur dependent hyperthermophilic Archaeon, which was isolated from a shallow submarine thermal spring. It has been successfully used in a two-stage fermenta...

    Authors: Mária Takács, András Tóth, Balázs Bogos, András Varga, Gábor Rákhely and Kornél L Kovács
    Citation: BMC Microbiology 2008 8:88
  43. Outer membrane vesicles (OMVs) are released from the outer membrane of many Gram-negative bacteria. These extracellular compartments are known to transport compounds involved in cell-cell signalling as well as...

    Authors: Vishaldeep K Sidhu, Frank-Jörg Vorhölter, Karsten Niehaus and Steven A Watt
    Citation: BMC Microbiology 2008 8:87
  44. Brucellosis, caused by members of the genus Brucella, remains one of the world's major zoonotic diseases. Six species have classically been recognised within the family Brucella largely based on a combination of ...

    Authors: Krishna K Gopaul, Mark S Koylass, Catherine J Smith and Adrian M Whatmore
    Citation: BMC Microbiology 2008 8:86
  45. Modification of teichoic acids with D-alanine by the products of the dlt operon protects Gram-positive bacteria against major antimicrobial host defense molecules such as defensins, cathelicidins, myeloperoxidase...

    Authors: Dirk Kraus, Silvia Herbert, Sascha A Kristian, Arya Khosravi, Victor Nizet, Friedrich Götz and Andreas Peschel
    Citation: BMC Microbiology 2008 8:85

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