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  1. Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection, claiming millions of lives annually. The virus infects various cells of the respiratory tract as well as resident inflam...

    Authors: Vira Bitko, Nicolle E Garmon, Tin Cao, Benjamin Estrada, John E Oakes, Robert N Lausch and Sailen Barik
    Citation: BMC Microbiology 2004 4:28
    Content type: Research article Published on:

  2. Pathogenic Yersinia species (Y. enterocolitica, Y. pestis, Y. pseudotuberculosis) share a t ype t hree s ecretion s ystem (TTSS) which allows translocation of effector proteins (called Yops) into host cells. It i...

    Authors: Gottfried Wilharm, Verena Lehmann, Wibke Neumayer, Janja Trček and Jürgen Heesemann
    Citation: BMC Microbiology 2004 4:27
    Content type: Research article Published on:

  4. Cell to cell signaling systems in Gram-negative bacteria rely on small diffusible molecules such as the N-acylhomoserine lactones (AHL). These compounds are involved in the production of antibiotics, exoenzymes, ...

    Authors: Daniel Martinelli, Gilles Grossmann, Urs Séquin, Helmut Brandl and Reinhard Bachofen
    Citation: BMC Microbiology 2004 4:25
    Content type: Research article Published on:

  8. The limited circulation of many of the agents that are likely to be used in a bioterrorism attack precludes the ready availability of positive controls. This means that only specialized laboratories can screen...

    Authors: Remy N Charrel, Bernard La Scola and Didier Raoult
    Citation: BMC Microbiology 2004 4:21
    Content type: Research article Published on:

  9. The phylogeny of the genus Methanobrevibacter was established almost 25 years ago on the basis of the similarities of the 16S rRNA oligonucleotide catalogs. Since then, many 16S rRNA gene sequences of newly isola...

    Authors: Abhijit S Dighe, Kamlesh Jangid, José M González, Vyankatesh J Pidiyar, Milind S Patole, Dilip R Ranade and Yogesh S Shouche
    Citation: BMC Microbiology 2004 4:20
    Content type: Research article Published on:

  10. Salmonella enterica and Campylobacter jejuni are amongst the more prevalent bacterial pathogens that cause foodborne diseases. These microorganisms are common contaminants of poultry and poultry products. This st...

    Authors: Gustavo Faúndez, Miriam Troncoso, Paola Navarrete and Guillermo Figueroa
    Citation: BMC Microbiology 2004 4:19
    Content type: Research article Published on:

  11. Shigella is the etiological agent of shigellosis, a disease responsible for more than 500,000 deaths of children per year, in developing countries. These pathogens colonize the intestinal colon, invade, spreading...

    Authors: Emerson da Motta Willer, Renato de Lourenço Lima and Loreny Gimenes Giugliano
    Citation: BMC Microbiology 2004 4:18
    Content type: Research article Published on:

  12. The Rio Grande River is the natural boundary between U.S. and Mexico from El Paso, TX to Brownsville, TX. and is one of the major water resources of the area. Agriculture, farming, maquiladora industry, domestic ...

    Authors: Jose Mendoza, James Botsford, Jose Hernandez, Anna Montoya, Roswitha Saenz, Adrian Valles, Alejandro Vazquez and Maria Alvarez
    Citation: BMC Microbiology 2004 4:17
    Content type: Research article Published on:

  13. The pathogenesis of bacterial vaginosis remains largely elusive, although some microorganisms, including Gardnerella vaginalis, are suspected of playing a role in the etiology of this disorder. Recently culture-i...

    Authors: Rita Verhelst, Hans Verstraelen, Geert Claeys, Gerda Verschraegen, Joris Delanghe, Leen Van Simaey, Catharine De Ganck, Marleen Temmerman and Mario Vaneechoutte
    Citation: BMC Microbiology 2004 4:16
    Content type: Research article Published on:

  16. The Bacillus subtilis glucokinase operon was predicted to be comprised of the genes, yqgP (now named gluP), yqgQ, and glcK. We have previously established a role for glcK in glucose metabolism. In the absence of ...

    Authors: Lili R Mesak, Felix M Mesak and Michael K Dahl
    Citation: BMC Microbiology 2004 4:13
    Content type: Research article Published on:

  17. We describe a novel application of microarray technology for comparative genomics of bacteria in which libraries of entire genomes rather than the sequence of a single genome or sets of genes are arrayed on th...

    Authors: Lixin Zhang, Usha Srinivasan, Carl F Marrs, Debashis Ghosh, Janet R Gilsdorf and Betsy Foxman
    Citation: BMC Microbiology 2004 4:12
    Content type: Methodology article Published on:

  18. Prodigiosin produced by Serratia marcescens is a promising drug owing to its reported characteristics of having antifungal, immunosuppressive and antiproliferative activity. From an industrial point of view the n...

    Authors: Anuradha V Giri, Nandini Anandkumar, Geetha Muthukumaran and Gautam Pennathur
    Citation: BMC Microbiology 2004 4:11
    Content type: Research article Published on:

  19. Enteropathogenic Escherichia coli (EPEC), mainly causing infantile diarrhoea, represents one of at least six different categories of diarrheagenic E. coli with corresponding distinct pathogenic schemes. The mecha...

    Authors: Roger Stephan, Nicole Borel, Claudio Zweifel, Miguel Blanco and Jesús E Blanco
    Citation: BMC Microbiology 2004 4:10
    Content type: Research article Published on:

  20. The thiomethyl group of S-adenosylmethionine is often recycled as methionine from methylthioadenosine. The corresponding pathway has been unravelled in Bacillus subtilis. However methylthioadenosine is subjected ...

    Authors: Agnieszka Sekowska, Valérie Dénervaud, Hiroki Ashida, Karine Michoud, Dieter Haas, Akiho Yokota and Antoine Danchin
    Citation: BMC Microbiology 2004 4:9
    Content type: Research article Published on:

  21. Chlamydia trachomatis is a prevalent sexually transmitted disease and the leading cause of infectious blindness in developing nations. It was not known if C. trachomatis-infection influenced metabolism of lipopro...

    Authors: Grant M Hatch and Grant McClarty
    Citation: BMC Microbiology 2004 4:8
    Content type: Research article Published on:

  22. Serology is often used for the diagnosis of Mycoplasma pneumoniae. It is important to identify specific antigens that can distinguish between the presence or absence of antibodies against M. pneumoniae. The two p...

    Authors: Mette Drasbek, Pernille K Nielsen, Kenneth Persson, Svend Birkelund and Gunna Christiansen
    Citation: BMC Microbiology 2004 4:7
    Content type: Research article Published on:

  23. Bacillus subtilis glucokinase (GlcK) (GenBank NP_390365) is an ATP-dependent kinase that phosphorylates glucose to glucose 6-phosphate. The GlcK protein has very low sequence identity (13.7%) to the Escherichia c...

    Authors: Lili R Mesak, Felix M Mesak and Michael K Dahl
    Citation: BMC Microbiology 2004 4:6
    Content type: Research article Published on:

  24. Histology and/or culture are generally considered the gold standard for the detection of H. pylori infection. Especially in children, these tests may result in a false negative outcome because of patchy distribut...

    Authors: Kathleen MB Vinette, Kathleen M Gibney, Roy Proujansky and Paul T Fawcett
    Citation: BMC Microbiology 2004 4:5
    Content type: Research article Published on:

  26. Sucrose density gradient centrifugation and cross-flow filtration methods have been developed and standardised for the safe and reproducible production of inactivated arbovirus antigens which are appropriate f...

    Authors: Alyssa T Pyke, Debra A Phillips, Teck F Chuan and Greg A Smith
    Citation: BMC Microbiology 2004 4:3
    Content type: Research article Published on:

  27. Deinococcus radiodurans R1 is one of the most radiation-resistant organisms known and is able to repair an unusually large amount of DNA damage without induced mutation. Single-stranded DNA-binding (SSB) protein ...

    Authors: Julie Malia Eggington, Nami Haruta, Elizabeth Anne Wood and Michael Matthew Cox
    Citation: BMC Microbiology 2004 4:2
    Content type: Research article Published on:

  28. Anaplasma phagocytophilum strains often vary in Msp2 expression, a situation assumed to be related to immune evasion. However, Msp2 is also an adhesin, and little is known about the role of endogenous msp2 transc...

    Authors: Diana G Scorpio, Karen Caspersen, Hiroyuki Ogata, Jinho Park and J Stephen Dumler
    Citation: BMC Microbiology 2004 4:1
    Content type: Research article Published on:

  29. Viral replication as well as an immunopathological component are assumed to be involved in the development of coxsackie B virus (CBV)-induced myocarditis. We observed that mycophenolic acid (MPA), the active m...

    Authors: Elizaveta Padalko, Erik Verbeken, Patrick Matthys, Joeri L Aerts, Erik De Clercq and Johan Neyts
    Citation: BMC Microbiology 2003 3:25
    Content type: Research article Published on:

  30. The transition metal molybdenum is essential for life. Escherichia coli imports this metal into the cell in the form of molybdate ions, which are taken up via an ABC transport system. In E. coli and other Proteob...

    Authors: David J Studholme and Richard N Pau
    Citation: BMC Microbiology 2003 3:24
    Content type: Research article Published on:

  31. Tandem repeats contained within coding regions can mediate phase variation when the repeated units change the reading frame of the coding sequence in a copy number dependent manner. Coding tandem repeats are t...

    Authors: Philip Jordan, Lori AS Snyder and Nigel J Saunders
    Citation: BMC Microbiology 2003 3:23
    Content type: Research article Published on:

  32. Bacterial mercury resistance is based on enzymatic reduction of ionic mercury to elemental mercury and has recently been demonstrated to be applicable for industrial wastewater clean-up. The long-term monitori...

    Authors: Andreas DM Felske, Wanda Fehr, Björg V Pauling, Harald von Canstein and Irene Wagner-Döbler
    Citation: BMC Microbiology 2003 3:22
    Content type: Research article Published on:

  33. Pseudomonas aeruginosa, an increasingly prevalent opportunistic pathogen, utilizes a type III secretion system for injection of toxins into host cells in order to initiate infection. A crucial component of this s...

    Authors: Max Nanao, Sylvie Ricard-Blum, Anne Marie Di Guilmi, David Lemaire, David Lascoux, Jacqueline Chabert, Ina Attree and Andréa Dessen
    Citation: BMC Microbiology 2003 3:21
    Content type: Research article Published on:

  35. To date PCR detection of Chlamydia pneumoniae DNA in atherosclerotic lesions from Danish patients has been unsuccessful. To establish whether non-detection was caused by a suboptimal DNA extraction method, we tes...

    Authors: Tina Mygind, Lars Østergaard, Svend Birkelund, Jes S Lindholt and Gunna Christiansen
    Citation: BMC Microbiology 2003 3:19
    Content type: Research article Published on:

  36. Bacterial macrofibers twist as they grow, writhe, supercoil and wind up into plectonemic structures (helical forms the individual filaments of which cannot be taken apart without unwinding) that eventually car...

    Authors: Neil H Mendelson, Patrick Shipman, Darshan Roy, Liling Chen and John J Thwaites
    Citation: BMC Microbiology 2003 3:18
    Content type: Research article Published on:

  37. In spite of Argentina having one of the highest frequencies of haemolytic uraemic syndrome (HUS), the incidence of Escherichia coli O157:H7 is low in comparison to rates registered in the US. Isolation of several...

    Authors: Pablo M Molina, Alberto E Parma and Marcelo E Sanz
    Citation: BMC Microbiology 2003 3:17
    Content type: Research article Published on:

  38. It is well known that expression of certain bacterial genes responds rapidly to such stimuli as exposure to toxic chemicals and physical agents. It is generally believed that the proteins encoded in these gene...

    Authors: Yuko Yamaguchi, Toshifumi Tomoyasu, Akiko Takaya, Mizue Morioka and Tomoko Yamamoto
    Citation: BMC Microbiology 2003 3:16
    Content type: Research article Published on:

  39. Currently, there are very few tools available for subtyping Brucella isolates for epidemiological trace-back. Subtyping is difficult because of the genetic homogeneity within the genus. Sequencing of the genomes ...

    Authors: Betsy J Bricker, Darla R Ewalt and Shirley M Halling
    Citation: BMC Microbiology 2003 3:15
    Content type: Research article Published on:

  40. Streptococcus pneumoniae possesses large zinc metalloproteinases on its surface. To analyse the importance in virulence of three of these metalloproteinases, intranasal challenge of MF1 outbred mice was carried o...

    Authors: Damiana Chiavolini, Guido Memmi, Tiziana Maggi, Francesco Iannelli, Gianni Pozzi and Marco R Oggioni
    Citation: BMC Microbiology 2003 3:14
    Content type: Research article Published on:

  44. Mycobacterium avium subspecies avium (M. avium) is frequently encountered in the environment, but also causes infections in animals and immunocompromised patients. In contrast, Mycobacterium avium subspecies para...

    Authors: John P Bannantine, Qing Zhang, Ling-Ling Li and Vivek Kapur
    Citation: BMC Microbiology 2003 3:10
    Content type: Research article Published on:

  45. Actin is required for the gene expression and morphogenesis of respiratory syncytial virus (RSV), a clinically important Pneumovirus of the Paramyxoviridae family. In HEp-2 cells, RSV infection also induces actin...

    Authors: Vira Bitko, Anja Oldenburg, Nicolle E Garmon and Sailen Barik
    Citation: BMC Microbiology 2003 3:9
    Content type: Research article Published on:

  47. We report cloning and characterization of a novel Leishmania infantum protein which we termed Lepp12, and we examine its possible implication in the interference with intramacrophage signaling pathways.

    Authors: Konstantina Fragaki, Bernard Ferrua, Baharia Mograbi, Julie Waldispühl and Joanna Kubar
    Citation: BMC Microbiology 2003 3:7
    Content type: Research article Published on:

  48. Ebola virus causes severe, often fatal hemorrhagic fever in humans. The mechanism of escape from cellular anti-viral mechanisms is not yet fully understood. The promyelocytic leukaemia (PML) associated nuclear...

    Authors: Asa Szekely Björndal, Laszlo Szekely and Fredrik Elgh
    Citation: BMC Microbiology 2003 3:6
    Content type: Research article Published on:

  49. Staphylococcus aureus infection of normal osteoblasts induces expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).

    Authors: Emily H Alexander, F Andrea Rivera, Ian Marriott, Juan Anguita, Kenneth L Bost and Michael C Hudson
    Citation: BMC Microbiology 2003 3:5
    Content type: Research article Published on:
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BMC Microbiology

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