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  1. Production of the gene transfer agent RcGTA in the α-proteobacterium Rhodobacter capsulatus is dependent upon the response regulator protein CtrA. Loss of this regulator has widespread effects on transcription in...

    Authors: Ryan G Mercer and Andrew S Lang
    Citation: BMC Microbiology 2014 14:71
    Content type: Research article Published on:

  2. The ethanol-producing bacterium Zymomonas mobilis has attracted considerable scientific and commercial interest due to its exceptional physiological properties. Shuttle vectors derived from native plasmids have p...

    Authors: Lok Yan So, Wen-yang Chen, Donnabella C Lacap-Bugler, Myriam Seemann and Rory M Watt
    Citation: BMC Microbiology 2014 14:68
    Content type: Research article Published on:

  3. Generalist bacterial pathogens, with the ability for environmental survival and growth, often face variable conditions during their outside-host period. Abiotic factors (such as nutrient deprivation) act as se...

    Authors: Lotta-Riina Sundberg, Heidi M T Kunttu and E Tellervo Valtonen
    Citation: BMC Microbiology 2014 14:67
    Content type: Research article Published on:

  4. Enterococci, ubiquitous colonizers of humans and other animals, play an increasingly important role in health-care associated infections (HAIs). It is believed that the recent evolution of two clinically relev...

    Authors: Ewa Sadowy and Aneta Luczkiewicz
    Citation: BMC Microbiology 2014 14:66
    Content type: Research article Published on:

  5. Nitric oxide (NO) is produced as part of the host immune response to bacterial infections, including urinary tract infections. The enzyme flavohemoglobin, coded by the hmp gene, is involved in protecting bacteria...

    Authors: Charlotte Sahlberg Bang, Annica Kinnunen, Marie Karlsson, Anna Önnberg, Bo Söderquist and Katarina Persson
    Citation: BMC Microbiology 2014 14:65
    Content type: Research article Published on:

  6. Successful viral infection requires the involvement of host cellular factors in their life cycle. Heat shock protein 70 (HSP70) can be recruited by numerous viruses to promote the folding, maturation, or assem...

    Authors: Jintao Gao, Shuqi Xiao, Xiaohong Liu, Liangliang Wang, Qianqian Ji, Delin Mo and Yaosheng Chen
    Citation: BMC Microbiology 2014 14:64
    Content type: Research article Published on:

  7. Staphylococcal protein A (spa) is an important virulence factor which enables Staphylococcus aureus to evade host immune responses. Genotypes known as “spa-types”, based on highly variable Xr region sequences of ...

    Authors: Antonina A Votintseva, Rowena Fung, Ruth R Miller, Kyle Knox, Heather Godwin, David H Wyllie, Rory Bowden, Derrick W Crook and A Sarah Walker
    Citation: BMC Microbiology 2014 14:63
    Content type: Research article Published on:

  8. Acinetobacter baumannii has emerged as an opportunistic nosocomial pathogen causing infections worldwide. One reason for this emergence is due to its natural ability to survive in the hospital environment, which...

    Authors: Yassine Nait Chabane, Mohamed Ben Mlouka, Stéphane Alexandre, Marion Nicol, Sara Marti, Martine Pestel-Caron, Jordi Vila, Thierry Jouenne and Emmanuelle Dé
    Citation: BMC Microbiology 2014 14:62
    Content type: Research article Published on:

  9. Smokers are more prone to oral infections than are non-smokers. Cigarette smoke reaches the host cells but also microorganisms present in the oral cavity. The contact between cigarette smoke and oral bacteria ...

    Authors: Abdelhabib Semlali, Kerstin Killer, Humidah Alanazi, Witold Chmielewski and Mahmoud Rouabhia
    Citation: BMC Microbiology 2014 14:61
    Content type: Research article Published on:

  10. The use of whole-genome sequencing in microbiology at a diagnostic level, although feasible, is still limited by the expenses associated and by the complex bioinformatics pipelines in data analyses. We describ...

    Authors: Veranja Liyanapathirana, Irene Ang, Dominic Tsang, Kitty Fung, Tak Keung Ng, Haokui Zhou and Margaret Ip
    Citation: BMC Microbiology 2014 14:60
    Content type: Research article Published on:

  11. Vibrio parahaemolyticus is frequently isolated from environmental and seafood samples and associated with gastroenteritis outbreakes in American, European, Asian and African countries. To distinguish between dif...

    Authors: Sara Urmersbach, Thomas Alter, Madura Sanjeevani Gonsal Koralage, Lisa Sperling, Gunnar Gerdts, Ute Messelhäusser and Stephan Huehn
    Citation: BMC Microbiology 2014 14:59
    Content type: Research article Published on:

  12. Listeria monocytogenes is a food-borne pathogen which is the causative agent of listeriosis and can be divided into three evolutionary lineages I, II and III. While all strains possess the well established virul...

    Authors: Evelyn M Clayton, Karen M Daly, Caitriona M Guinane, Colin Hill, Paul D Cotter and Paul R Ross
    Citation: BMC Microbiology 2014 14:58
    Content type: Research article Published on:

  14. Bacterial species coexist commonly in mixed communities, for instance those occurring in microbial infections of humans. Interspecies effects contribute to alterations in composition of communities with respec...

    Authors: Marc Rüger, Mandy Ackermann and Udo Reichl
    Citation: BMC Microbiology 2014 14:56
    Content type: Research article Published on:

  15. Environmental screening programs are used to find new enzymes that may be utilized in large-scale industrial processes. Among microbial sources of new enzymes, the rationale for screening fungal endophytes as ...

    Authors: Bita Zaferanloo, Shatabdi Bhattacharjee, Mahmood M Ghorbani, Peter J Mahon and Enzo A Palombo
    Citation: BMC Microbiology 2014 14:55
    Content type: Research article Published on:

  16. Corynebacterium glutamicum cg1790/pgk encodes an enzyme active as a 3-phosphoglycerate kinase (PGK) (EC 2.7.2.3) catalyzing phosphoryl transfer from 1,3-biphosphoglycerate (bPG) to ADP to yield 3-phosphoglycerat...

    Authors: Gajendar Komati Reddy and Volker F Wendisch
    Citation: BMC Microbiology 2014 14:54
    Content type: Research article Published on:

  17. Mixed microbial infections of the respiratory tracts with P. aeruginosa and A. fumigatus capable of producing biofilms are commonly found in cystic fibrosis patients. The primary objective of this study was to de...

    Authors: Elias K Manavathu, Dora L Vager and Jose A Vazquez
    Citation: BMC Microbiology 2014 14:53
    Content type: Research article Published on:

  18. Meyerozyma guilliermondii (anamorph Candida guilliermondii) and Meyerozyma caribbica (anamorph Candida fermentati) are closely related species of the genetically heterogenous M. guilliermondii complex. Conventio...

    Authors: Wahengbam Romi, Santosh Keisam, Giasuddin Ahmed and Kumaraswamy Jeyaram
    Citation: BMC Microbiology 2014 14:52
    Content type: Methodology article Published on:

  19. Extensive use of antibiotics has fostered the emergence of superbugs that are resistant to multidrugs, which becomes a great healthcare and public concern. Previous studies showed that quorum sensing signal DS...

    Authors: Yinyue Deng, Amy Lim, Jasmine Lee, Shaohua Chen, Shuwen An, Yi-Hu Dong and Lian-Hui Zhang
    Citation: BMC Microbiology 2014 14:51
    Content type: Research article Published on:

  20. Rhodosporidium toruloides is a β-carotenoid accumulating, oleaginous yeast that has great biotechnological potential. The lack of reliable and efficient genetic manipulation tools have been a major hurdle blocki...

    Authors: Chong Mei John Koh, Yanbin Liu, Moehninsi, Minge Du and Lianghui Ji
    Citation: BMC Microbiology 2014 14:50
    Content type: Research article Published on:

  21. Pathogenic serotypes of Vibrio cholerae cause the life-threatening diarrheal disease cholera. The increasing development of bacterial resistances against the known antibiotics necessitates the search for new anti...

    Authors: Galina Sergeev, Sambit Roy, Michael Jarek, Viktor Zapolskii, Dieter E Kaufmann, Ranjan K Nandy and Werner Tegge
    Citation: BMC Microbiology 2014 14:49
    Content type: Research article Published on:

  22. To obtain insights into Escherichia coli O157:H7 (O157) survival mechanisms in the bovine rumen, we defined the growth characteristics and proteome of O157 cultured in rumen fluid (RF; pH 6.0-7.2 and low volatile...

    Authors: Indira T Kudva, Thaddeus B Stanton and John D Lippolis
    Citation: BMC Microbiology 2014 14:48
    Content type: Research article Published on:

  23. Haemophilus influenzae colonizes the nasopharynx as a commensal. Strain-specific factors allow some strains to migrate to particular anatomical niches, such as the middle ear, bronchi or blood, and induce diseas...

    Authors: Nadiah Ishak, Alexandra Tikhomirova, Stephen J Bent, Garth D Ehrlich, Fen Z Hu and Stephen P Kidd
    Citation: BMC Microbiology 2014 14:47
    Content type: Research article Published on:

  24. The antimetabolite mangotoxin is a key factor in virulence of Pseudomonas syringae pv. syringae strains which cause apical necrosis of mango trees. Previous studies showed that mangotoxin biosynthesis is governed...

    Authors: Víctor J Carrión, Menno van der Voort, Eva Arrebola, José A Gutiérrez-Barranquero, Antonio de Vicente, Jos M Raaijmakers and Francisco M Cazorla
    Citation: BMC Microbiology 2014 14:46
    Content type: Research article Published on:

  26. Dengue virus (DENV) still poses a global public health threat, and no vaccine or antiviral therapy is currently available. Antibody plays distinct roles in controlling DENV infections. Neutralizing antibody is...

    Authors: Ke-Yu Song, Hui Zhao, Zhen-You Jiang, Xiao-Feng Li, Yong-Qiang Deng, Tao Jiang, Shun-Ya Zhu, Pei-Yong Shi, Bo Zhang, Fu-Chun Zhang, E-De Qin and Cheng-Feng Qin
    Citation: BMC Microbiology 2014 14:44
    Content type: Research article Published on:

  27. Imbalanced feeding regimes may initiate gastrointestinal and metabolic diseases in endangered felids kept in captivity such as cheetahs. Given the crucial role of the host’s intestinal microbiota in feed ferme...

    Authors: Anne AMJ Becker, Myriam Hesta, Joke Hollants, Geert PJ Janssens and Geert Huys
    Citation: BMC Microbiology 2014 14:43
    Content type: Research article Published on:

  28. Laribacter hongkongensis is a Gram-negative, urease-positive bacillus associated with invasive bacteremic infections in liver cirrhosis patients and fish-borne community-acquired gastroenteritis and traveler’s d...

    Authors: Lifeng Xiong, Jade LL Teng, Rory M Watt, Biao Kan, Susanna KP Lau and Patrick CY Woo
    Citation: BMC Microbiology 2014 14:42
    Content type: Research article Published on:

  29. Coxiella burnetii causes Q fever in humans and Coxiellosis in animals; symptoms range from general malaise to fever, pneumonia, endocarditis and death. Livestock are a significant source of human infection as th...

    Authors: Talima Pearson, Heidie M Hornstra, Remy Hilsabeck, Lauren T Gates, Sonora M Olivas, Dawn M Birdsell, Carina M Hall, Sabrina German, James M Cook, Meagan L Seymour, Rachael A Priestley, Ashley V Kondas, Christine L Clark Friedman, Erin P Price, James M Schupp, Cindy M Liu…
    Citation: BMC Microbiology 2014 14:41
    Content type: Research article Published on:

  30. Chlamydia trachomatis is an obligate intracellular human pathogen causing ocular and urogenital infections that are a significant clinical and public health concern. This bacterium uses a type III secretion (T3S...

    Authors: Maria da Cunha, Catarina Milho, Filipe Almeida, Sara V Pais, Vítor Borges, Rui Maurício, Maria José Borrego, João Paulo Gomes and Luís Jaime Mota
    Citation: BMC Microbiology 2014 14:40
    Content type: Research article Published on:

  31. Huanglongbing (HLB) or citrus greening is a devastating disease of citrus. The gram-negative bacterium Candidatus Liberibacter asiaticus (Las) belonging to the α-proteobacteria is responsible for HLB in North Ame...

    Authors: Sunitha Kogenaru, Qing Yan, Nadia Riera, M Caroline Roper, Xiaoling Deng, Timothy A Ebert, Michael Rogers, Michael E Irey, Gerhard Pietersen, Charles M Rush and Nian Wang
    Citation: BMC Microbiology 2014 14:39
    Content type: Research article Published on:

  32. The aim of this paper was to develop a reverse transcription loop-mediated isothermal amplification (RT-LAMP) method for rapid, sensitive and inexpensive detection of astrovirus.

    Authors: Bo-Yun Yang, Xiao-Lu Liu, Yu-Mei Wei, Jing-Qi Wang, Xiao-Qing He, Yi Jin and Zi-Jian Wang
    Citation: BMC Microbiology 2014 14:38
    Content type: Research article Published on:

  33. Latent tuberculosis infection (LTBI) relies on a homeostasis of macrophages and Mycobacterium tuberculosis (Mtb). The small heat shock protein, Mtb Hsp16.3 (also known as latency-associated antigen), plays an imp...

    Authors: Qing-Lin Meng, Fei Liu, Xing-Yuan Yang, Xiao-Mei Liu, Xia Zhang, Chun Zhang and Zong-De Zhang
    Citation: BMC Microbiology 2014 14:37
    Content type: Research article Published on:

  34. The raw goat milk microbiota is considered a good source of novel bacteriocinogenic lactic acid bacteria (LAB) strains that can be exploited as an alternative for use as biopreservatives in foods. The constant...

    Authors: Luana Martins Perin and Luís Augusto Nero
    Citation: BMC Microbiology 2014 14:36
    Content type: Research article Published on:

  35. A wealth of microbial eukaryotes is adapted to life in oxygen-deficient marine environments. Evidence is accumulating that some of these eukaryotes survive anoxia by employing dissimilatory nitrate reduction, ...

    Authors: Peter Stief, Silvia Fuchs-Ocklenburg, Anja Kamp, Cathrine-Sumathi Manohar, Jos Houbraken, Teun Boekhout, Dirk de Beer and Thorsten Stoeck
    Citation: BMC Microbiology 2014 14:35
    Content type: Research article Published on:

  36. In this study we employed the TAP tag purification method coupled with mass spectrometry analysis to identify proteins that co-purify with Escherichia coli RNase R during exponential growth and after temperature ...

    Authors: Michal Malecki, Cátia Bárria and Cecilia M Arraiano
    Citation: BMC Microbiology 2014 14:34
    Content type: Research article Published on:

  39. The community-associated methicillin-resistant S. aureus (CA-MRSA) ST93 clone is becoming dominant in Australia and is clinically highly virulent. In addition, sepsis and skin infection models demonstrate that ST...

    Authors: Kyra YL Chua, Ian R Monk, Ya-Hsun Lin, Torsten Seemann, Kellie L Tuck, Jessica L Porter, Justin Stepnell, Geoffrey W Coombs, John K Davies, Timothy P Stinear and Benjamin P Howden
    Citation: BMC Microbiology 2014 14:31
    Content type: Research article Published on:

  40. Polyoxypeptin A was isolated from a culture broth of Streptomyces sp. MK498-98 F14, which has a potent apoptosis-inducing activity towards human pancreatic carcinoma AsPC-1 cells. Structurally, polyoxypeptin A is...

    Authors: Yanhua Du, Yemin Wang, Tingting Huang, Meifeng Tao, Zixin Deng and Shuangjun Lin
    Citation: BMC Microbiology 2014 14:30
    Content type: Research article Published on:

  41. In an effort to reconstitute the NAD+ synthetic pathway in Escherichia coli (E. coli), we produced a set of gene knockout mutants with deficiencies in previously well-defined NAD+ de novo and salvage pathways. Un...

    Authors: Wei-Ren Dong, Cen-Cen Sun, Guan Zhu, Shi-Hua Hu, Li-Xin Xiang and Jian-Zhong Shao
    Citation: BMC Microbiology 2014 14:29
    Content type: Research article Published on:

  42. Lactobacillus rhamnosus is a non-starter lactic acid bacterium that plays a significant role during cheese ripening, leading to the formation of flavor. In long-ripened cheeses it persists throughout the whole t...

    Authors: Camilla Lazzi, Silvia Turroni, Andrea Mancini, Elisa Sgarbi, Erasmo Neviani, Patrizia Brigidi and Monica Gatti
    Citation: BMC Microbiology 2014 14:28
    Content type: Research article Published on:

  43. Mycoplasma pneumoniae (M. pneumoniae) is one of the major etiological agents for community-acquired pneumonia (CAP) in all age groups. The early host response to M. pneumoniae infection relies on the concerted r...

    Authors: Shuxian Li, Xuejing Li, Yingshuo Wang, Jun Yang, Zhimin Chen and Shigang Shan
    Citation: BMC Microbiology 2014 14:27
    Content type: Research article Published on:

  44. Pyocyanin (PCN), an extracellular product of Pseudomonas aeruginosa and a blue redox active secondary metabolite, plays an important role in invasive pulmonary infection. However, the detailed inflammatory respon...

    Authors: Wenshu Chai, Jia Zhang, Yan Duan, Dianzhu Pan, Wei Liu, Ying Li, Xue Yan and Baiyi Chen
    Citation: BMC Microbiology 2014 14:26
    Content type: Research article Published on:

  45. The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based ap...

    Authors: Fiona Fouhy, R Paul Ross, Gerald F Fitzgerald, Catherine Stanton and Paul D Cotter
    Citation: BMC Microbiology 2014 14:25
    Content type: Research article Published on:

  46. Antibiotics in current use target a surprisingly small number of cellular functions: cell wall, DNA, RNA, and protein biosynthesis. Targeting of novel essential pathways is expected to play an important role i...

    Authors: Ruggero Rusmini, Davide Vecchietti, Raffaella Macchi, Faustino Vidal-Aroca and Giovanni Bertoni
    Citation: BMC Microbiology 2014 14:24
    Content type: Research article Published on:

  47. Histoplasma capsulatum and Pneumocystis organisms cause host infections primarily affecting the lung tissue. H. capsulatum is endemic in the United States of America and Latin American countries. In special envi...

    Authors: Antonio E González-González, Cécile M Aliouat-Denis, José A Ramírez-Bárcenas, Christine Demanche, Muriel Pottier, Laura E Carreto-Binaghi, Haroon Akbar, Sandra Derouiche, Magalie Chabé, El Moukhtar Aliouat, Eduardo Dei-Cas and Maria Lucia Taylor
    Citation: BMC Microbiology 2014 14:23
    Content type: Research article Published on:

  48. Diguanylate cyclases (DGCs) regulate biofilm formation and motility in bacteria by synthesizing the second messenger cyclic di-GMP (c-di-GMP) in response to environmental stimuli. DGC enzymatic activity is bel...

    Authors: Jessica L Hunter, Geoffrey B Severin, Benjamin J Koestler and Christopher M Waters
    Citation: BMC Microbiology 2014 14:22
    Content type: Research article Published on:

  49. Different polymorphisms have been described as markers to classify the lineages of the Mycobacterium tuberculosis complex. The analysis of nine single nucleotide polymorphisms (SNPs) was used to describe seven SN...

    Authors: Adriana Cabal, Mark Strunk, José Domínguez, María Antonia Lezcano, María Asunción Vitoria, Miguel Ferrero, Carlos Martín, María José Iglesias and Sofía Samper
    Citation: BMC Microbiology 2014 14:21
    Content type: Research article Published on:

  50. Celiac disease is characterized by enhanced intestinal paracellular permeability due to alterations of function and expression of tight junction (TJ) proteins including ZO-1, Claudin-1 and Occludin. Polyamines...

    Authors: Antonella Orlando, Michele Linsalata, Maria Notarnicola, Valeria Tutino and Francesco Russo
    Citation: BMC Microbiology 2014 14:19
    Content type: Research article Published on:
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BMC Microbiology

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