Featured article: High-virulence of P. aeruginosa in cystic fibrosis patients

Pseudomonas aeruginosa is a common pathogen in the lungs of cystic fibrosis (CF) patients and is associated with increased morbidity, reduction in quality of life and mortality. This study quantifies the within-patient variation in the production of three virulence-associated secretions in the CF strain of P. aeruginosa. While investigating the effects of these variations in acute infections of an insect host model, the study concludes that they can result in high virulence sub-populations persisting in patients with chronic CF infections.

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Aims and scope

BMC Microbiology is an open access, peer-reviewed journal that considers articles on analytical and functional studies of prokaryotic and eukaryotic microorganisms, viruses and small parasites, as well as host and therapeutic responses to them and their interaction with the environment.

 Editor

  • Alexandros Houssein, BioMed Central

Section Editors

  • Stéphane Aymerich, INRA
  • Stephen Forsythe, Nottingham Trent University
  • Ralf Heermann, Ludwig-Maximilians-Universitaet
  • Igor Mokrousov, St. Petersburg Pasteur Institute
  • Hirotada Mori, Nara Institute of Science and Technology
  • David Nelson, University of Rhode Island
  • Marco Ventura, University of Parma
  • Raffaele Zarrilli, Università di Napoli Federico II
  • Jizhong Zhou, University of Oklahoma

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