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Table 2 Identification of plasmid-encoded drug-resistant gene in non-typeable Haemophilus influenzae isolates

From: Molecular characterization of multidrug-resistant non-typeable Haemophilus influenzae with high-level resistance to cefuroxime, levofloxacin, and trimethoprim-sulfamethoxazole

Isolate

Identification

Accession

Greatest identity (%)

Lowest E-value

β-lactamase

 ED04

TEM-1

WP_000027057.1

100.0

0

 ED06

TEM-1

WP_000027057.1

100.0

0

 ED07

TEM-1

WP_000027057.1

100.0

0

 ED08

TEM-1

WP_000027057.1

100.0

0

 ED10

TEM-1

WP_000027057.1

100.0

0

 ED15

TEM-1

WP_000027057.1

100.0

0

 ED22

ROB-1

WP_005618523.1

90.7

5.2E-64

 

ROB-11

WP_132995818.1

90.5

7.0E-40

 ED23

ROB-1

WP_005618523.1

99.3

0

 

TEM-1

(aa 150–185)

WP_000027057.1

91.7

9.0E-22

 

TEM-1

(aa 274–286)

WP_000027057.1

84.6

2.0E-06

Tetracycline efflux

 ED02

TetR/AcrR family

WP_005751845.1

59.1

2.2E-53

 ED07

Tet(B)

WP_001089072.1

99.8

0

 ED08

Tet(B)

WP_001089072.1

99.8

0

 ED10

Tet(B)

WP_001089068.1

100.0

0

 ED15

Tet(B)

WP_001089072.1

100.0

0

Macrolide efflux

 ED04

Mef(A)

WP_024410015.1

100.0

6.0E-41

  1. Drug-resistant genes were assessed using BLASTx and compared with sequences available in the RefSeq database of the National Center for Biotechnology Information
  2. Abbreviation: aa Amino acid