Table 2 List of the representative genes located in the hypermutated regions
M.i.27 subgroup | Â | |
|---|---|---|
Gene | Locus tag* | Function |
gyrA | OCU_RS25025 | DNA gyrase subunit A |
cyp144 | OCU_RS25050 | cytochrome P450 Cyp144 |
cwsA | OCU_RS25055 | cell wall synthesis protein CwsA |
citE | OCU_RS37365 | citrate lyase subunit beta |
zwf | OCU_RS37375 | IMP dehydrogenase |
hrpA | OCU_RS37390 | ATP-dependent RNA helicase |
otsB | OCU_RS45365 | trehalose-phosphate phosphatase |
htdY | OCU_RS45370 | 3-hydroxyacyl-thioester dehydratase HtdY |
lpqD | OCU_RS45375 | histidine phosphatase family protein |
eccC2 | OCU_RS49810 | type VII secretion protein EccC |
mviN | OCU_RS49890 | putative peptidoglycan biosynthesis protein MviN |
rsmA | OCU_RS49900 | anti-sigma-M factor RsmA |
trxB_2 | OCU_RS49905 | thioredoxin reductase |
MP-MIP group | Â | |
Gene | Locus tag* | Function |
paaG | OCU_RS31460 | enoyl-CoA hydratase |
mce3A | OCU_RS31625 | MCE-family protein Mce3A |
mce3B | OCU_RS31630 | Mce family protein Mce3B |
mce3C | OCU_RS31635 | Mce family protein Mce3C |
mce3D | OCU_RS31640 | Mce family protein Mce3D |
lprM | OCU_RS31645 | MCE-family protein Mce3E |
hmd | OCU_RS31690 | 5,10-methylene tetrahydromethanopterin reductase |
cyp143 | OCU_RS31715 | putative cytochrome P450 Cyp143 |
fadE3 | OCU_RS31935 | acyl-CoA dehydrogenase |
acd | OCU_RS32010 | acyl-CoA dehydrogenase |
fadE33 | OCU_RS32080 | acyl-CoA dehydrogenase |
cyp124 | OCU_RS32180 | methyl-branched lipid omega-hydroxylase |
mhpB | OCU_RS32235 | 2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase |
cyp143 | OCU_RS32255 | putative cytochrome P450 Cyp143 |
fadE22 | OCU_RS32275 | acyl-CoA dehydrogenase FadE22 |
mmpL13 | OCU_RS33545 | Transport protein MmpL13 |
Both M.i.27 subgroup and MP-MIP group | ||
Gene | Locus tag* | Function |
mmpL12 | OCU_RS28435 | putative transport protein MmpL12 |
cyp123 | OCU_RS28470 | putative cytochrome P450 Cyp123 |
acg | OCU_RS34620 | putative NADPH nitroreductase Acg |