Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice

Table 2 Abundance of common bacterial families

Family	% control^a	% ACA^a	ACA : control^b
Muribaculaceae	30.4 (21.5, 43.3)	48.1^** (35.3, 61.8)	1.8^**
Lachnospiraceae	26.6 (16.3, 41.6)	23.9^† (9.6, 37.4)	1.3
Ruminococcaceae	14.2 (9.0, 19.0)	11.6^* (6.9, 15.6)	1.1
Lactobacillaceae	9.5 (1.2, 17.0)	2.6^* (1.0, 8.2)	0.31^*
Erysipelotrichaceae	1.4 (0.3, 6.2)	0.5^* (0.2, 2.2)	0.42^†

^aMedian and interquartile range of the relative abundance of the top five most abundant bacterial families in control and ACA-treated mice
^bthe ratio of median spike-adjusted abundances in ACA-treated mice versus control mice
^† P<0.1 via Mann Whitney U test
^* P<0.05
^** P<0.001

ISSN: 1471-2180