The human jejunum has an endogenous microbiota that differs from those in the oral cavity and colon

BMC Microbiology

Table 3 Average composition of the jejunum by genus and its correlation with bacterial load

Rank	Composition	Pearson Correlation with Log Bacterial Load	P-value of Correlation	Genus	Phylum
Rank	Jejunum	Pearson Correlation with Log Bacterial Load	P-value of Correlation	Genus	Phylum
1	28.0%	0.036	0.880	Streptococcus	Firmicutes
2	12.5%	−0.296	0.205	Prevotella	Bacteroidetes
3	6.7%	0.158	0.507	Veillonella	Firmicutes
4	6.5%	−0.236	0.316	Escherichia	Proteobacteria
5	5.7%	0.188	0.428	Fusobacterium	Fusobacteria
6	5.2%	0.163	0.492	Haemophilus	Proteobacteria
7	2.8%	0.201	0.396	Actinomyces	Actinobacteria
8	2.3%	−0.554	0.011	Rothia	Actinobacteria
9	2.3%	−0.428	0.060	Leptotrichia	Fusobacteria
10	2.0%	0.101	0.672	Gemella	Firmicutes
11	2.0%	−0.264	0.261	Neisseria	Proteobacteria
12	1.8%	0.336	0.148	Klebsiella	Proteobacteria
13	1.8%	0.345	0.136	Citrobacter	Proteobacteria
14	1.3%	0.196	0.407	Actinobacillus	Proteobacteria
15	0.9%	0.355	0.125	Granulicatella	Firmicutes
16	0.9%	0.381	0.097	Enterobacter	Proteobacteria
17	0.8%	−0.158	0.507	Bacteroides	Bacteroidetes
18	0.8%	−0.483	0.031	Lachnoclostridium	Firmicutes
19	0.7%	0.319	0.170	Porphyromonas	Bacteroidetes
20	0.6%	0.270	0.250	Megasphaera	Firmicutes
21	0.6%	0.337	0.146	Lactobacillus	Firmicutes
22	0.6%	−0.460	0.041	Campylobacter	Proteobacteria
23	0.6%	0.338	0.145	Oribacterium	Firmicutes
24	0.5%	−0.237	0.316	Parascardovia	Actinobacteria
25	0.5%	−0.496	0.026	Ralstonia	Proteobacteria
26	0.3%	−0.003	0.991	Corynebacterium	Actinobacteria
27+	12.4%			all other genera

Percentages represent average metagenomic abundance of the genus over all 20 subjects, as a percentage of all bacteria (col 2). Linear Pearson correlation of genus abundance with log of the DNA-Based total microbe count (col 3). The Pearson correlation coefficient was used to determine the P-value (column 4) for the null hypothesis that there is no correlation between genus abundance and bacterial load. Only Rothia, Lachnoclostridium, Campylobacter and Ralstonia differed significantly from the null hypothesis (shaded cells). Columns 5–8 display the genus and its taxonomy

ISSN: 1471-2180