Table 4 M. avium genes selected for intracellular confirmation
Gene | Function | Motif | M.tb homology | Secreted in M.tb |
|---|---|---|---|---|
MAV_1178 | Hypothetical protein | WXG100: ESAT-6 Type VII secretion target | Rv2347c | Unknown |
MAV_1177 | Hypothetical protein | WXG100: ESAT-6 Type VII secretion target | Rv2346c | Y |
MAV_0628 | Hypothetical protein | MHB: coiled-coil molecule that binds free haem in mycobacterial cytoplasm to deliver it to membrane proteins for shuttling through the membrane | None | N |
MAV_4394 | Hypothetical protein | Serine esterase, Cutinase family protein | Rv3451 | Unknown |
MAV_0502 | Hypothetical protein | None | None | N |
MAV_0516 | Cold shock protein | CSPA: probably involved in cold acclimation process | Rv3648c | Y |
MAV_4077 | Hypothetical protein | CsbD: bacterial general stress response protein | None | N |
MAV_1356 | Hypothetical protein | 98 % Homologues to M. tuberculosis calmodulin-like protein. DUF: proteins with unknown function restricted to Actinobacteria | Rv1211 | Y |
MAV_1419 | Hypothetical protein | DUF: proteins with unknown function restricted to Actinobacteria | None | N |
MAV_0398 | Hypothetical protein | PkhH_C: found as the periplasmic domain of the bacterial protein kinase PknH | Rv3705c | Y |