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Fig. 1 | BMC Microbiology

Fig. 1

From: The MarR-like protein PchR (YvmB) regulates expression of genes involved in pulcherriminic acid biosynthesis and in the initiation of sporulation in Bacillus subtilis

Fig. 1

Involvement of the yvmC-cypX operon in pulcherriminic acid biosynthesis. a Genetic organisation of the yvnB, yvnA, yvmC-cypX and yvmBA genes in the B. subtilis genome. The function of the corresponding encoded proteins is indicated. b Scheme of the pulcherriminic acid biosynthetic pathway in B. subtilis. The cyclodipeptide synthase YvmC utilizes charged leucyl tRNAs as substrate to catalyze the formation of cyclo-L-leucyl-L-leucyl (cLL). The cytochrome P450 CypX is implicated in the transformation of cLL into pulcherriminic acid. Pulcherriminic acid is excreted from the cells by an unknown mechanism and chelates free Fe(III) by a non-enzymatic reaction to form an extracellular red pigment, the pulcherrimin

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BMC Microbiology

ISSN: 1471-2180

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