Table 1 Histological examination of Mtb-infected mouse lungs
From: senX3-independent contribution of regX3 to Mycobacterium tuberculosis virulence
Strain | Peribronchiolar inflammation | Degree of inflammation | Extension of inflammation into airway | Lymphoid aggregates | Bronchioles inflamed | No. of bronchioles per slide | % of inflamed bronchioles |
|---|---|---|---|---|---|---|---|
CDC1551 | yes | mild to mod | no | yes | 3.75 | 37.25 | 10 |
senX3::Tn | no | none | no | n/a | 0.25 | 45 | 1 |
senX3::Tn Comp | yes | mild to mod | yes | yes | 6.75 | 40.75 | 17 |
regX3::Tn | no | none | no | n/a | 3.25 | 36.75 | 9 |
regX3::Tn Comp | yes | mild | yes | yes | 7.6 | 40.2 | 19 |