Figure 2

Distribution of S . Enteritidis 147 wild-type strain and ΔSPI1&2 and SPI1&2o, ΔSPI1-5 mutants in the liver and spleen of orally infected chickens. Y axis, average log CFU/g of organ ± SD. a, b - t-test different at p < 0.05 in comparison to the group infected with the wild-type S. Enteritidis (a) or the ΔSPI1-5 mutant (b). Abbreviations: wt - wild-type S. Enteritidis 147; ΔSPI1-5: mutant from which all major 5 SPIs have been removed; ΔSPI1&2: mutant from which SPI1 and SPI2 have been removed; SPI1&2 only: mutant with only SPI1 and SPI2 retained.