Proliferation rate of epitopes stimulated splenocytes. 5 × 104 splenocytes and 105 mitomycin-treated cells were mixed and stimulated with phage particles containing epitopes of OmpL1 (A) or LipL41 (B) to test the proliferation of the cells. Response to each antigen was presented as the mean value of three independent experiments. Splenocytes were isolated from PBS control mice to determine if the responses were OmpL1- or LipL41-specific. The cells stimulated with ConA and wild-type phages were used as controls. The data were representative of three independent experiments. Mix1 stands for the data from the epitope mixture of OmpL1 or LipL41 stimulating splenocytes from OmpL1- or LipL41-immunized mice. Mix2 stand for the data from the epitope mixture of both OmpL1 and LipL41 stimulating the splenocytes from OmpL1- or LipL41- immunized mice.