Table 1 Gene list of significantly up- and down-regulated genes in the HP0256 mutant based on the array experiment.
TIGR orf no. | Putative gene product (gene) | Expression ratio | p-value |
|---|---|---|---|
Down-regulated genes: | |||
Hp26695-0092 | type II restriction enzyme M protein (hsdM) | 0.15 | 0.02 |
HpJ99-1132 | dimethyladenosine transferase | 0.17 | 0.00 |
Hp26695-0093 | alpha-2-fucosyltransferase | 0.22 | 0.01 |
Hp26695-0229 | outer membrane protein (omp6) ( hopA ) | 0.24 | 0.01 |
Hp26695-0492 | flagellar sheath associated protein ( hpaA3 ) | 0.26 | 0.00 |
Hp26695-1210 | serine acetyltransferase (cysE) | 0.26 | 0.00 |
Hp26695-1587 | conserved hypothetical protein | 0.27 | 0.00 |
Hp26695-1208 | ulcer associated adenine specific DNA methyltransferase | 0.27 | 0.00 |
Hp26695-0610 | toxin-like outer membrane protein | 0.32 | 0.03 |
Hp26695-1207 | hypothetical protein | 0.34 | 0.01 |
HpJ99-0055 | putative | 0.35 | 0.03 |
Hp26695-1211 | hypothetical protein | 0.37 | 0.00 |
Hp26695-0430 | hypothetical protein | 0.40 | 0.04 |
Hp26695-1492 | conserved hypothetical nifU-like protein | 0.41 | 0.01 |
Hp26695-0805 | lipooligosaccharide 5G8 epitope biosynthesis-associated protein | 0.42 | 0.02 |
Hp26695-1203a | Preprotein translocase subunit SecE | 0.43 | 0.01 |
Hp26695-1219 | hypothetical protein | 0.43 | 0.04 |
Hp26695-0711 | hypothetical protein | 0.45 | 0.01 |
Hp26695-1180 | pyrimidine nucleoside transport protein (nupC) | 0.46 | 0.03 |
Hp26695-0502 | hypothetical protein | 0.46 | 0.03 |
Hp26695-1589 | conserved hypothetical protein | 0.47 | 0.01 |
Hp26695-0094 | alpha-2-fucosyltransferase | 0.49 | 0.02 |
Hp26695-1334 | hypothetical protein | 0.49 | 0.01 |
Hp26695-0415 | conserved hypothetical integral membrane protein | 0.49 | 0.01 |
Hp26695-0340 | hypothetical protein | 0.49 | 0.00 |
Hp26695-0798 | molybdenum cofactor biosynthesis protein C (moaC) | 0.49 | 0.03 |
Hp26695-0892 | conserved hypothetical protein | 0.50 | 0.03 |
Hp26695-0331 | cell division inhibitor ( minD ) | 0.59 | 0.04 |
Up-regulated genes: | |||
Hp26695-0115 | flagellin B ( flaB ) | 1.91 | 0.03 |
Hp26695-0979 | cell divison protein ( ftsZ ) | 1.92 | 0.00 |
Hp26695-1469 | outer membrane protein ( omp31 ) ( hopV ) | 1.96 | 0.00 |
Hp26695-1243 | outer membrane protein ( omp28 ) ( babA ) | 1.96 | 0.00 |
Hp26695-0386 | hypothetical protein | 2.01 | 0.00 |
Hp26695-0831 | conserved hypothetical ATP binding protein | 2.04 | 0.01 |
Hp26695-0952 | conserved hypothetical integral membrane protein | 2.05 | 0.00 |
Hp26695-0311 | hypothetical protein | 2.16 | 0.00 |
Hp26695-0720 | hypothetical protein | 2.16 | 0.02 |
Hp26695-0943 | D-amino acid dehydrogenase (dadA) | 2.18 | 0.01 |
Hp26695-0896 | outer membrane protein ( omp19 ) ( babB ) | 2.18 | 0.00 |
Hp26695-0590 | ferredoxin oxidoreductase, beta subunit | 2.23 | 0.01 |
Hp26695-0589 | ferredoxin oxidoreductase, alpha subunit | 2.27 | 0.01 |
Hp26695-1340 | biopolymer transport protein ( exbD ) | 2.30 | 0.00 |
Hp26695-1339 | biopolymer transport protein ( exbB ) | 2.36 | 0.00 |
Hp26695-0747 | conserved hypothetical protein | 2.44 | 0.03 |
Hp26695-0310 | conserved hypothetical protein | 2.48 | 0.00 |
Hp26695-1322 | hypothetical protein | 2.57 | 0.03 |
Hp26695-1076 | hypothetical protein | 2.59 | 0.00 |
Hp26695-1524 | hypothetical protein | 2.68 | 0.05 |
Hp26695-0721 | hypothetical protein | 2.99 | 0.00 |
Hp26695-0744 | pseudogene | 3.08 | 0.00 |
Hp26695-0719 | hypothetical protein | 3.34 | 0.01 |
Hp26695-0954 | oxygen-insensitive NAD(P)H nitroreductase | 3.53 | 0.00 |