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  1. Thiamine triphosphate (ThTP) exists in most organisms and might play a role in cellular stress responses. In E. coli, ThTP is accumulated in response to amino acid starvation but the mechanism of its synthesis...

    Authors: Tiziana Gigliobianco, Bernard Lakaye, Alexander F Makarchikov, Pierre Wins and Lucien Bettendorff

    Citation: BMC Microbiology 2008 8:16

    Content type: Research article

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  2. The heme acquisition machinery in Streptococcus pyogenes is believed to consist of the surface proteins, Shr and Shp, and heme-specific ATP-binding cassette transporter HtsABC. Shp has been shown to rapidly trans...

    Authors: Hui Zhu, Mengyao Liu and Benfang Lei

    Citation: BMC Microbiology 2008 8:15

    Content type: Research article

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  3. Helicobacter pylori colonizes the human stomach and is the etiological agent of peptic ulcer disease. All three H. pylori strains that have been sequenced to date contain a potential operon whose products share h...

    Authors: Priyanka Brahmachary, Ge Wang, Stéphane L Benoit, Michael V Weinberg, Robert J Maier and Timothy R Hoover

    Citation: BMC Microbiology 2008 8:14

    Content type: Research article

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  4. The autoinducer-2 (AI-2) group of signalling molecules are produced by both Gram positive and Gram negative bacteria as the by-product of a metabolic transformation carried out by the LuxS enzyme. They are the...

    Authors: Agnes Bodor, Bettina Elxnat, Verena Thiel, Stefan Schulz and Irene Wagner-Döbler

    Citation: BMC Microbiology 2008 8:13

    Content type: Research article

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  5. The Yersinia enterocolitica flagellar master regulator FlhD/FlhC affects the expression levels of non-flagellar genes, including 21 genes that are involved in central metabolism. The sigma factor of the flagellar...

    Authors: Megan K Townsend, Nathan J Carr, Jyoti G Iyer, Shelley M Horne, Penelope S Gibbs and Birgit M Prüß

    Citation: BMC Microbiology 2008 8:12

    Content type: Research article

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  6. Lamivudine is an oral nucleoside analogue widely used for the treatment of chronic hepatitis B. The main limitation of lamivudine use is the selection of resistant mutations that increases with time of utiliza...

    Authors: Marcelle Bottecchia, Francisco JD Souto, Kycia MR Ó, Marcia Amendola, Carlos E Brandão, Christian Niel and Selma A Gomes

    Citation: BMC Microbiology 2008 8:11

    Content type: Research article

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  7. Salmonella can reside in healthy animals without the manifestation of any adverse effects on the carrier. If raw products of animal origin are not handled properly during processing or cooked to a proper temperat...

    Authors: Attila Karsi, Kevin Howe, Tasha B Kirkpatrick, Robert Wills, R Hartford Bailey and Mark L Lawrence

    Citation: BMC Microbiology 2008 8:10

    Content type: Research article

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  8. The administration of non-antifungal drugs during patient hospitalization might be responsible for discrepancies between in vitro and in vivo susceptibility to antifungals. Propofol is often administered to inten...

    Authors: Sofia Costa-de-Oliveira, Ricardo Araujo, Ana Silva-Dias, Cidália Pina-Vaz and Acácio Gonçalves Rodrigues

    Citation: BMC Microbiology 2008 8:9

    Content type: Research article

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  9. The response regulator DegU and its cognate histidine kinase DegS constitute a two-component system in the Gram-positive soil bacterium Bacillus subtilis. Unphosphorylated and phosphorylated forms of DegU are kno...

    Authors: Kensuke Tsukahara and Mitsuo Ogura

    Citation: BMC Microbiology 2008 8:8

    Content type: Research article

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  10. Pyoverdines (PVDs) are high affinity siderophores, for which the molecular mechanisms of biosynthesis, uptake and regulation have been extensively studied in Pseudomonas aeruginosa PAO1. However, the extent to wh...

    Authors: Christina D Moon, Xue-Xian Zhang, Sandra Matthijs, Mathias Schäfer, Herbert Budzikiewicz and Paul B Rainey

    Citation: BMC Microbiology 2008 8:7

    Content type: Research article

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  11. Microbial fuel cells (MFCs) are devices that exploit microorganisms to generate electric power from organic matter. Despite the development of efficient MFC reactors, the microbiology of electricity generation...

    Authors: Shun'ichi Ishii, Takefumi Shimoyama, Yasuaki Hotta and Kazuya Watanabe

    Citation: BMC Microbiology 2008 8:6

    Content type: Research article

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  12. The chlamydial developmental cycle involves the alternation between the metabolically inert elementary body (EB) and the replicating reticulate body (RB). The triggers that mediate the interchange between thes...

    Authors: Alexander Hoare, Peter Timms, Patrik M Bavoil and David P Wilson

    Citation: BMC Microbiology 2008 8:5

    Content type: Hypothesis

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  13. Autoinducer 2 (AI-2), a widespread by-product of the LuxS-catalyzed S-ribosylhomocysteine cleavage reaction in the activated methyl cycle, has been suggested to serve as an intra- and interspecies signaling mo...

    Authors: Min Li, Amer E Villaruz, Viveka Vadyvaloo, Daniel E Sturdevant and Michael Otto

    Citation: BMC Microbiology 2008 8:4

    Content type: Research article

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  14. The endoglycosidase EndoS and the cysteine proteinase SpeB from the human pathogen Streptococcus pyogenes are functionally related in that they both hydrolyze IgG leading to impairment of opsonizing antibodies an...

    Authors: Maria Allhorn, Arne Olsén and Mattias Collin

    Citation: BMC Microbiology 2008 8:3

    Content type: Research article

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  15. The social amoeba Dictyostelium discoideum executes a multicellular development program upon starvation. This morphogenetic process requires the differential regulation of a large number of genes and is coordinat...

    Authors: Juan J Vicente, María Galardi-Castilla, Ricardo Escalante and Leandro Sastre

    Citation: BMC Microbiology 2008 8:1

    Content type: Research article

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  16. AP65 is a prominent adhesin of Trichomonas vaginalis that mediates binding of parasites to host vaginal epithelial cells (VECs). AP65 with no secretion signal sequence, membrane targeting peptide, and anchoring m...

    Authors: Ana F Garcia and JF Alderete

    Citation: BMC Microbiology 2007 7:116

    Content type: Research article

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  17. Most studies of the vaginal microflora have been based on culture or on qualitative molecular techniques. Here we applied existing real-time PCR formats for Lactobacillus crispatus, L. gasseri and Gardnerella vag...

    Authors: Ellen De Backer, Rita Verhelst, Hans Verstraelen, Mohammed A Alqumber, Jeremy P Burton, John R Tagg, Marleen Temmerman and Mario Vaneechoutte

    Citation: BMC Microbiology 2007 7:115

    Content type: Research article

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  18. The IgA1 protease of Streptococcus pneumoniae is a proteolytic enzyme that specifically cleaves the hinge regions of human IgA1, which dominates most mucosal surfaces and is the major IgA isotype in serum. This p...

    Authors: Francesca De Paolis, Elisa Beghetto, Andrea Spadoni, Francesca Montagnani, Franco Felici, Marco R Oggioni and Nicola Gargano

    Citation: BMC Microbiology 2007 7:113

    Content type: Research article

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  19. Enterococci have emerged as a significant cause of nosocomial infections in many parts of the world over the last decade. The most common enterococci strains present in clinical isolates are E. faecalis and E. fa...

    Authors: Chan Yean Yean, Lee Su Yin, Pattabhiraman Lalitha and Manickam Ravichandran

    Citation: BMC Microbiology 2007 7:112

    Content type: Research article

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  20. Along with angioplasty, autologus vein grafts are commonly used for artery bypass grafting in patients with advanced arterial stenosis and drug-resistant angina pectoris. Although initially a successful proced...

    Authors: Geoffrey TL Kloppenburg, Rick de Graaf, Gert ELM Grauls, Cathrien A Bruggeman and Frank R Stassen

    Citation: BMC Microbiology 2007 7:111

    Content type: Research article

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  21. Sunflower downy mildew is a major disease caused by the obligatory biotrophic oomycete Plasmopara halstedii. Little is known about the molecular mechanisms underlying its pathogenicity. In this study we used a ge...

    Authors: Mohamed Fouad Bouzidi, Francis Parlange, Paul Nicolas and Said Mouzeyar

    Citation: BMC Microbiology 2007 7:110

    Content type: Research article

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  22. Shiga toxins 1 and 2 (Stx1 and Stx2) are bacteriophage-encoded proteins that have been associated with hemorrhagic colitis, hemolytic uremic syndrome and other severe disease conditions. Stx1 and Stx2 are gene...

    Authors: James E Lee, Junelina Reed, Malcolm S Shields, Kathleen M Spiegel, Larry D Farrell and Peter P Sheridan

    Citation: BMC Microbiology 2007 7:109

    Content type: Research article

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  23. The metagenomic analysis of microbial communities holds the potential to improve our understanding of the role of microbes in clinical conditions. Recent, dramatic improvements in DNA sequencing throughput and...

    Authors: Andreas Sundquist, Saharnaz Bigdeli, Roxana Jalili, Maurice L Druzin, Sarah Waller, Kristin M Pullen, Yasser Y El-Sayed, M Mark Taslimi, Serafim Batzoglou and Mostafa Ronaghi

    Citation: BMC Microbiology 2007 7:108

    Content type: Methodology article

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  24. Sporothrix schenckii is a pathogenic, dimorphic fungus, the etiological agent of sporotrichosis, a subcutaneous lymphatic mycosis. Dimorphism in S. schenckii responds to second messengers such as cAMP and calcium...

    Authors: Liz Valle-Aviles, Shirley Valentin-Berrios, Ricardo R Gonzalez-Mendez and Nuri Rodriguez-del Valle

    Citation: BMC Microbiology 2007 7:107

    Content type: Research article

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  25. An available whole genome sequence for Aspergillus flavus provides the opportunity to characterize factors involved in pathogenicity and to elucidate the regulatory networks involved in aflatoxin biosynthesis. Fu...

    Authors: Zhu-Mei He, Michael S Price, Gregory R OBrian, D Ryan Georgianna and Gary A Payne

    Citation: BMC Microbiology 2007 7:104

    Content type: Research article

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  26. Hepatitis B virus (HBV) isolates have been classified in eight genotypes, A to H, which exhibit distinct geographical distributions. Genotypes A, D and F are predominant in Brazil, a country formed by a misceg...

    Authors: Francisco CA Mello, Francisco JD Souto, Leticia C Nabuco, Cristiane A Villela-Nogueira, Henrique Sergio M Coelho, Helena Cristina F Franz, Joao Carlos P Saraiva, Helaine A Virgolino, Ana Rita C Motta-Castro, Mabel MM Melo, Regina MB Martins and Selma A Gomes

    Citation: BMC Microbiology 2007 7:103

    Content type: Research article

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  27. Legionella pneumophila is a facultative intracellular bacterium, capable of replicating within the phagosomes of macrophages and monocytes, but little is known about its interaction with human lung epithelial cel...

    Authors: Hiromitsu Teruya, Futoshi Higa, Morikazu Akamine, Chie Ishikawa, Taeko Okudaira, Koh Tomimori, Naofumi Mukaida, Masao Tateyama, Klaus Heuner, Jiro Fujita and Naoki Mori

    Citation: BMC Microbiology 2007 7:102

    Content type: Research article

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    The Erratum to this article has been published in BMC Microbiology 2011 11:136

  28. Reuterin produced from glycerol by Lactobacillus reuteri, a normal inhabitant of the human intestine, is a broad-spectrum antimicrobial agent. It has been postulated that reuterin could play a role in the probiot...

    Authors: Valentine Cleusix, Christophe Lacroix, Sabine Vollenweider, Marc Duboux and Gwenaelle Le Blay

    Citation: BMC Microbiology 2007 7:101

    Content type: Research article

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  29. Bordetella holmesii is a human pathogen closely related to B. pertussis, the etiological agent of whooping cough. It is able to cause disease in immunocompromised patients, but also whooping cough-like symptoms i...

    Authors: Stefanie Link, Karin Schmitt, Dagmar Beier and Roy Gross

    Citation: BMC Microbiology 2007 7:100

    Content type: Research article

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  30. Community acquired (CA) methicillin-resistant Staphylococcus aureus (MRSA) increasingly causes disease worldwide. USA300 has emerged as the predominant clone causing superficial and invasive infections in childre...

    Authors: Sarah K Highlander, Kristina G Hultén, Xiang Qin, Huaiyang Jiang, Shailaja Yerrapragada, Edward O Mason Jr, Yue Shang, Tiffany M Williams, Régine M Fortunov, Yamei Liu, Okezie Igboeli, Joseph Petrosino, Madhan Tirumalai, Akif Uzman, George E Fox, Ana Maria Cardenas…

    Citation: BMC Microbiology 2007 7:99

    Content type: Research article

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  31. For typing of Staphylococcus aureus, DNA sequencing of the repeat region of the protein A (spa) gene is a well established discriminatory method for outbreak investigations. Recently, it was hypothesized that thi...

    Authors: Alexander Mellmann, Thomas Weniger, Christoph Berssenbrügge, Jörg Rothgänger, Michael Sammeth, Jens Stoye and Dag Harmsen

    Citation: BMC Microbiology 2007 7:98

    Content type: Research article

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  32. Global patterns of gene expression of Escherichia coli K-12 during growth transitions have been deeply investigated, however, comparable studies of E. coli O157:H7 have not been explored, particularly with respec...

    Authors: Teresa M Bergholz, Lukas M Wick, Weihong Qi, James T Riordan, Lindsey M Ouellette and Thomas S Whittam

    Citation: BMC Microbiology 2007 7:97

    Content type: Research article

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  33. Environmental modulation of gene expression in Yersinia pestis is critical for its life style and pathogenesis. Using cDNA microarray technology, we have analyzed the global gene expression of this deadly pathoge...

    Authors: Yanping Han, Jingfu Qiu, Zhaobiao Guo, He Gao, Yajun Song, Dongsheng Zhou and Ruifu Yang

    Citation: BMC Microbiology 2007 7:96

    Content type: Research article

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  34. Bovine tuberculosis is a zoonotic problem in pastoral cattle and communities in Uganda. Tuberculin tests in pastoral cattle had shown a high herd but low animal prevalence, with a high proportion of avian reac...

    Authors: J Oloya, R Kazwala, A Lund, J Opuda-Asibo, B Demelash, E Skjerve, TB Johansen and B Djønne

    Citation: BMC Microbiology 2007 7:95

    Content type: Research article

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  35. The risk of mortality from pneumonia caused by Streptococcus pneumoniae is increased in patients with cirrhosis. However, the specific pneumococcal virulence factors and host immune defects responsible for this f...

    Authors: Katie L Propst-Graham, Laurel C Preheim, Elizabeth A Vander Top, Mary U Snitily and Martha J Gentry-Nielsen

    Citation: BMC Microbiology 2007 7:94

    Content type: Research article

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  36. Aeromonas spp. have been regarded as "emerging pathogens". Aeromonads possess multifactorial virulence and the production of many of these virulence determinants is associated with high cell density, a phenomenon...

    Authors: Kamlesh Jangid, Richard Kong, Milind S Patole and Yogesh S Shouche

    Citation: BMC Microbiology 2007 7:93

    Content type: Research article

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  37. Paracoccidioides brasiliensis ecology is not completely understood, although several pieces of evidence point to the soil as its most probable habitat. The present study aimed to investigate the fungal growth, co...

    Authors: Gisela Ramos Terçarioli, Eduardo Bagagli, Gabriela Martins Reis, Raquel Cordeiro Theodoro, Sandra De Moraes Gimenes Bosco, Severino Assis da Graça Macoris and Virgínia Bodelão Richini-Pereira

    Citation: BMC Microbiology 2007 7:92

    Content type: Research article

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  38. Coxiella burnetii contains the IS1111 transposase which is present 20 times in the Nine Mile phase I (9Mi/I) genome. A single PCR primer that binds to each IS element, and primers specific to a region ~500-bp ups...

    Authors: Amy M Denison, Herbert A Thompson and Robert F Massung

    Citation: BMC Microbiology 2007 7:91

    Content type: Research article

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  39. The predominant food borne pathogen in the western world today is Campylobacter. Campylobacter specific bacteriophages (phages) have been proposed as an alternative agent for reducing the burden of Campylobacter ...

    Authors: Vinni Mona Hansen, Hanne Rosenquist, Dorte Lau Baggesen, Stanley Brown and Bjarke Bak Christensen

    Citation: BMC Microbiology 2007 7:90

    Content type: Research article

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  40. Susceptibility to Bordetella pertussis infection varies widely. These differences can partly be explained by genetic host factors. HcB-28 mice are more resistant to B. pertussis infection than C3H mice, which cou...

    Authors: Sander Banus, Rob J Vandebriel, Jeroen LA Pennings, Eric R Gremmer, Piet W Wester, Henk J van Kranen, Timo M Breit, Peter Demant, Frits R Mooi, Barbara Hoebee and Tjeerd G Kimman

    Citation: BMC Microbiology 2007 7:88

    Content type: Research article

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  41. Salmonella enterica serovar Enteritidis has emerged as a significant foodborne pathogen throughout the world and is commonly characterized by phage typing. In Canada phage types (PT) 4, 8 and 13 predominate and i...

    Authors: Adam B Olson, Ashleigh K Andrysiak, Dobryan M Tracz, Jean Guard-Bouldin, Walter Demczuk, Lai-King Ng, Anne Maki, Frances Jamieson and Matthew W Gilmour

    Citation: BMC Microbiology 2007 7:87

    Content type: Research article

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  42. Rotavirus is a worldwide cause of infectious infantile diarrhea that claims over 600,000 lives annually. Recently, two new vaccine candidates have been developed but their efficacy in developing countries, sti...

    Authors: Neha Pant, Harold Marcotte, Harald Brüssow, Lennart Svensson and Lennart Hammarström

    Citation: BMC Microbiology 2007 7:86

    Content type: Research article

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  43. Recent research suggests that alcohol-based skin antiseptics exhibit their efficacy on the resident skin flora of the forehead in less than 10 minutes. That is why we have looked at the efficacy of two ethanol...

    Authors: Günter Kampf, Frank-Albert Pitten, Peter Heeg and Bärbel Christiansen

    Citation: BMC Microbiology 2007 7:85

    Content type: Research article

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  44. Salmonella enteritidis is suggested to translocate in the small intestine. In vivo it induces gene expression changes in the ileal mucosa and Peyer's patches. Stimulation of Salmonella translocation by dietary pr...

    Authors: Wendy Rodenburg, Jaap Keijer, Evelien Kramer, Susanne Roosing, Carolien Vink, Martijn B Katan, Roelof van der Meer and Ingeborg MJ Bovee-Oudenhoven

    Citation: BMC Microbiology 2007 7:84

    Content type: Research article

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