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Fig. 5 | BMC Microbiology

Fig. 5

From: High-resolution genomics identifies pneumococcal diversity and persistence of vaccine types in children with community-acquired pneumonia in the UK and Ireland

Fig. 5

Phylogenetic tree generated from penicillin-binding protein 2b amino acid sequences. Coloured squares represent the presence of mutations previously described to confer an increase in MIC. Number of total amino acid modifications, penicillin and amoxicillin susceptibility, serotype, and number of isolates are also depicted. Variants highlighted in blue present a low number of overall amino acid modification while containing the three key modifications described in the CARD database to reduce susceptibility to beta-lactams

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