Ultraviolet C inactivation of Coxiella burnetii for production of a structurally preserved whole cell vaccine antigen

Table 3 Distribution of C. burnetii NMII morphological forms in untreated and UVC treated suspensions

Treatment	Time before or after treatment (h)	Number of bacteria measured (n)	²C. burnetii NMII morphological forms (%)
Treatment	Time before or after treatment (h)	Number of bacteria measured (n)	SCV	LCV
none	-1	27	70	30
	+ 24	27	41	59
	+ 48	23	52	48
¹UVC	+ 1	26	35	65
	+ 24	24	21	79
	+ 48	27	18	82

¹C. burnetii NMII was untreated or UVC treated at 100 µW/cm² for 20 min and incubated for 1 h, 24 or 48 h
²C. burnetii small cell variants (SCV) and large cell variants (LCV) were distinguished based on diameter (nm)

ISSN: 1471-2180