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Fig. 6 | BMC Microbiology

Fig. 6

From: Clostridium butyricum inhibits the inflammation in children with primary nephrotic syndrome by regulating Th17/Tregs balance via gut-kidney axis

Fig. 6

C. butyricum alleviated the immune inflammatory response in PNS through the HO-1/STAT3/RORγt signaling pathway. The mRNA levels of Keap1 (A), Nrf2 (B), HO-1 (C), JAK2 (D), STAT3 (E), and RORγt (F) in the kidney tissues. Representative western blot images and statistical results of HO-1 (G,H), JAK2 (G,I), STAT3 (G,J), and RORγt (G,K) expressions of protein levels in the kidney tissues. HO-1/STAT3/RORγt pathway diagram (L). Data were expressed as mean±SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. All experiments were performed in triplicate

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BMC Microbiology

ISSN: 1471-2180

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