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Table 3 Pathways significantly depleted in MCS

From: Metagenomic gut microbiome analysis of Japanese patients with multiple chemical sensitivity/idiopathic environmental intolerance

Definition

Pathway ID

p-value

Glycine, serine and threonine metabolism

ko00260

0.00003892

Inositol phosphate metabolism

ko00562

0.0005803

Aminoacyl-tRNA biosynthesis

ko00970

0.00062303

Insect hormone biosynthesis

ko00981

0.00071718

Selenocompound metabolism

ko00450

0.00132236

Amino acid related enzymes

ko01007

0.00160922

Arginine biosynthesis

ko00220

0.00171663

RNA polymerase

ko03020

0.00183047

Valine, leucine and isoleucine biosynthesis

ko00290

0.00195105

Histidine metabolism

ko00340

0.00195105

C5-Branched dibasic acid metabolism

ko00660

0.00361257

Vitamin B6 metabolism

ko00750

0.00383386

Global maps only

 

0.00457197

Thiamine metabolism

ko00730

0.00680488

Cysteine and methionine metabolism

ko00270

0.00994852

Autophagy—yeast

ko04138

0.01048819

Exosome

ko04147

0.01291053

Nitrogen metabolism

ko00910

0.01291053

Prenyltransferases

ko01006

0.01291053

Ubiquitin system

ko04121

0.01293742

Ribosome

ko03011

0.01429422

Ribosome

ko03010

0.01429422

Terpenoid backbone biosynthesis

ko00900

0.01660993

Steroid degradation

ko00984

0.01661341

Isoquinoline alkaloid biosynthesis

ko00950

0.01745052

Purine metabolism

ko00230

0.02019539

One carbon pool by folate

ko00670

0.02019539

Carbon fixation in photosynthetic organisms

ko00710

0.02019539

GABAergic synapse

ko04727

0.02019539

Glutamatergic synapse

ko04724

0.02222404

Translation factors

ko03012

0.02330197

Messenger RNA biogenesis

ko03019

0.02330197

Protein processing

 

0.02442413

Arabinogalactan biosynthesis—Mycobacterium

ko00572

0.02442413

Valine, leucine, and isoleucine degradation

ko00280

0.02807024

Cofactor metabolism

 

0.02807024

Pantothenate and CoA biosynthesis

ko00770

0.03074865

Cell cycle—Caulobacter

ko04112

0.03074865

Tryptophan metabolism

ko00380

0.03216668

Proteasome

ko03051

0.03363934

Novobiocin biosynthesis

ko00401

0.03516819

Glyoxylate and dicarboxylate metabolism

ko00630

0.03675485

D-Arginine and D-ornithine metabolism

ko00472

0.03675485

Fatty acid degradation

ko00071

0.03840094

Tropane, piperidine and pyridine alkaloid biosynthesis

ko00960

0.04010811

Propanoate metabolism

ko00640

0.04187801

Insulin resistance

ko04931

0.04187801

Proteoglycans in cancer

ko05205

0.04758114

  1. MCS multiple chemical sensitivity, HC healthy controls