Restoration of gut dysbiosis through Clostridium butyricum and magnesium possibly balance blood glucose levels: an experimental study

Table 1 Pre and post treatment Mean ± SD values of random blood glucose levels of Albino Rats induced diabetic with streptozotocin

Groups	Pre Treatment Mean ± SD	Post Treatment Mean ± SD	Percent change (%)	P value
Week 1
G₀	206.6 ± 67.7	246.1 ± 17.1	19.1	0.203
G₁	206.6 ± 67.7	189.3 ± 32.6	8.4	0.431
G₂	231.7 ± 101.3	255.2 ± 34.3	10.1	0.534
G₃	126 ± 7.07	213 ± 7.07	69.0	0.429
Week 2
G₀	206.6 ± 67.7	260.1 ± 13.3	25.9	0.024
G₁	206.6 ± 67.7	142.3 ± 10.9	31.1	0.052
G₂	231.7 ± 101.3	328.5 ± 28.29	41.8	0.077
G₃	126 ± 7.07	348.7 ± 7.4	176.7	0.001
Week 3
G₀	206.6 ± 67.7	370 ± 22.3	79.1	0.005
G₁	206.6 ± 67.7	85.1 ± 3.8	58.8	0.006
G₂	231.7 ± 101.3	354.2 ± 17.6	52.9	0.061
G₃	126 ± 7.07	288.5 ± 7.07	129.0	0.008

G₀: Metformin (100 mg/kg/day) with a standard basal diet
G₁: Clostridium butyricum (probiotic) (1.5 × 10⁵ CFU/day) with standard basal diet
G₂: Magnesium (500 mg/kg/day)
G₃:Clostridium butyricum (probiotic) (1.5 × 10⁵ CFU/day) and magnesium (300 mg/kg/day) in combination with a standard basal diet

ISSN: 1471-2180