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Fig. 3 | BMC Microbiology

Fig. 3

From: Human-derived bacterial strains mitigate colitis via modulating gut microbiota and repairing intestinal barrier function in mice

Fig. 3

Human-derived bacteria restored gut barrier function in DSS-induced colitis model. (a, b) Relative level of FITC-dextran in serum of DSS (a) and TNBS (b) treated mice. (c, d) qPCR quantification of mRNA levels of Tjp1 (c) and F11r (d) in the colonic tissue. Gapdh served as an endogenous control. (e, f) Representative immunofluorescence images of JAM-A (e) and its statistical quantification (f). (g, h) Representative immunofluorescence images of Occludin (g) and its statistical quantification (h). (i) qPCR quantification of mRNA levels of Muc2. n = 5–10 mice per group. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 vs. DSS + PBS group by ANOVA followed by LSD post hoc test. LR: Lactobacillus rhamnosus, LP: Lactobacillus plantarum, PA: Pediococcus acidilactici, EF: Enterococcus faecium, EC: Escherichia coli

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BMC Microbiology

ISSN: 1471-2180

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