Skip to main content
Fig. 2 | BMC Microbiology

Fig. 2

From: Phenotypic, molecular, and in silico characterization of coumarin as carbapenemase inhibitor to fight carbapenem-resistant Klebsiella pneumoniae

Fig. 2

Carbapenemase enzyme inhibition assay (A) Comparison of percentages of meropenem hydrolysis in coumarin treated and untreated supernatants (co-incubation) (B) Comparison of percentages of meropenem hydrolysis in the supernatant of K. Pneumoniae grown in the presence and the absence of 500 or 1000 µg/mL coumarin (co-culture). EDTA was added to inhibit MBLs and to differentiate the action of MBL from that of serine-based class A and D carbapenemases. *** indicates P < 0.001

Back to article page

BMC Microbiology

ISSN: 1471-2180

Contact us