Fig. 5

Key Genes and Cellular Processes in C. albicans Virulence. Key genes identified in this study play pivotal roles in critical cellular processes crucial for the virulence and survival of C. albicans. These processes encompass morphological transitions, including adhesion, dimorphism, hyphae formation, invasion, and biofilm formation. Additionally, the genes contribute to phenotypic switching, regulating the transition between white and opaque phases. They also form the cellular scaffold, orchestrating essential functions such as temperature sensing, sugar transport, cell wall structure, and cell cycle progression. Moreover, these genes influence fitness traits, including pH regulation, stress response, and zinc and calcium homeostasis. Their significance in these vital cellular processes underscores their potential as promising antifungal targets for combatting C. albicans infections