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Table 1 Baseline characteristics, laboratory data, and outcomes of seven COVID-19 patients with Col-CRKP admitted in ICU

From: Outbreak of colistin and carbapenem-resistant Klebsiella pneumoniae ST16 co-producing NDM-1 and OXA-48 isolates in an Iranian hospital

Patient

Patient-1

Patient-2

Patient-3

Patient-4

Patient-5

Patient-6

Patient-7

Age / years

59

67

40

35

75

24

44

Gender

Male

Female

Male

Female

Female

Female

Female

BMI (kg/m2)

29.4

31.1

39.2

31.9

31.2

29.4

32

Symptom duration before hospital admission

Cough, shortness of breath, chills, diarrhea, anorexia

Shortness of breath

Fever, chills, cough, nausea and vomiting, stuffy nose

Shortness of breath, muscle pain

Cough, shortness of breath, anorexia

Fever, cough, shortness of breath, stuffy nose, conjunctival redness

Fever, shortness of breath, drowsiness, anorexia, muscle pain

Underlying diseases

Blood pressure

Blood pressure

Pregnant

Diabetes, CHD

Pregnant

CKD

Steroid

MTP /

DX

MTP

MTP /

DXM

MTP

MTP

MTP

MTP /

DXM

Tocilizumab

Yes

Yes

No

Yes

No

No

Yes

Remdesivir

Yes

Yes

No

No

No

No

No

Invasive procedures

Urinary catheter, Gastric tube

Urinary catheter, Gastric tube

Urinary catheter

Urinary catheter, Gastric tube, PICC

Urinary catheter, Gastric tube

Urinary catheter, Gastric tube

Urinary catheter, Gastric tube

Surgery

No

No

No

Yes

No

Yes

No

Laboratory data: At ICU admission/ at microbial sampling time

 White blood cells count (109/ml)

6800 / 1000

9100 / 13,600

12,800 / 14,500

6300 / 12,300

9500 / 12,600

8400 / 19,900

13,000 / 34,900

 C-reactive protein (mg/dl)

78 / 86

76 / 3

50 / 4

86 / 5

84 / 54

71 / 54

70 / 2

 Neutrophils

93.4 / 90

88.1 / 92.6

85.2 / 85

82.1 / 76.3

87.5 / 95.5

88.9 / 90.5

89.9 / 87.8

 Cratinin

0.9 / 0.7

1.1 / 0.8

1.1 / 0.7

0.8 / 0.7

1.3 / 0.9

0.7 / 0.7

0.8 / 0.9

Fever (≥39) At ICU admission/ at microbial sampling time

No / Yes

No / No

No / Yes

No / Yes

No / Yes

No / Yes

No / No

Infection type

UTI

VAP

UTI

Cervicitis

VAP

Cervicitis

UTI

Specimen type

Urine

Tracheal

Urine

Endocervical

Tracheal

Endocervical

Urine and stool

Mechanical ventilation / days

No

Yes / 8

No

Yes / 15

Yes / 12

Yes / 18

Yes / 2

Length of hospital stay, days

31

14

20

17

14

24

40

Length of ICU stay, days

29

12

15

16

12

24

39

Time from ICU admission to superinfection, days

26

11

14

13

8

9

15

Outcomes

Died

Died

Died

Died

Died

Died

Died

  1. MTP Methyl-prednisolone: DXM Dexamethasone: PICC Peripherally Inserted Central Catheter: CHD Chronic heart disease: CKD Chronic Kidney disease: BMI (kg/m2) BMI, body mass index: UTI Urinary tract infection: VAP Ventilator-associated pneumonia