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Table 5 The synergistic effect between gentamicin and the methylated Phaseolus vulgaris seed protein (MPP) on different pathogenic bacteria

From: Mapping pathogenic bacteria resistance against common antibiotics and their potential susceptibility to methylated white kidney bean protein

Microorganism

Inhibition zone diameter (mm)

Theoreticalc

Microorganism effect

Genta (20 µg/ml)

MPPb (20 µg/ml)

MPP + Gent (10 + 10 µg/ml)

G + M (10 + 10 µg/ml)

Staph pasteuri

8.0 j ± 0.22

14.0f ± 0.08

18.9 b ± 0.14

11

13.6 b ± 4.49

S. pyogenes

2.5 m ± 0.16

17.0 d ± 0.16

20.0 a ± 0.22

9.75

13.2 c ± 7.66

S. Typhimurium

8.0 j ± 0.08

16.0 e ± 0.45

19.0 b ± 0.43

12

14.3 a ± 4.65

K. pneumoniae 2

3.0 m ± 0.22

10.0 h ± 0.16

9.0 i ± 0.41

6.5

7.3 f ± 3.13

K. oxytoca

4.0 l ± 0.82

16.0 e ± 0.08

16.0 e ± 0.17

10

12.0 d ± 5.67

E. coli 2

4.0 l ± 0.82

12.0 g ± 0.36

14.0 f ± 0.82

8

10.0 e ± 4.35

P. aeruginosa

5.0 k ± 0.37

16.0 e ± 0.41

18.0 c ± 0.08

10.5

13.0 c ± 5.72

Antibacterial effect

4.9 c ± 2.08

14.4 b ± 2.42

16.4 a ± 3.61

  
  1. aGent Gentamicin
  2. bMPP Modified Phaseolus vulgaris protein
  3. cTheoretical G + M: The calculated value of the inhibition zone induced by the two single (10 + 10 µg/ml) treatments each of antibiotic and MPP against tested bacteria