Emergence of multidrug-resistant Bacillus spp. derived from animal feed, food and human diarrhea in South-Eastern Bangladesh

Table 1 Antibiotic MICs and MBC of Bacillus species strains isolated from animal feed, food and diarrhea

Antibiotics	Bacterial strains →	B. cereus		B. subtilis		B. amyloliquefaciens		B. licheniformis		B. thuringiensis		B. megaterium		B. coagulans
Antibiotics	MIC range tested (µg/mL)	MIC (µg/mL)	MBC (µg/mL)	MIC (µg/mL)	MBC (µg/mL)	MIC (µg/mL)	MBC (µg/mL)	MIC (µg/mL)	MBC (µg/mL)	MIC (µg/mL)	MBC (µg/mL)	MIC (µg/mL)	MBC (µg/mL)	MIC (µg/mL)	MBC (µg/mL)
PG	0.25–32	> 32	> 32	0.5	1	0.5	1	> 32	> 32	> 32	> 32	0.25	0.5	0.25	0.5
AMC	0.01–0.5	0.06	0.12	0.06	0.12	0.06	0.12	0.06	0.12	0.06	0.12	0.06	0.12	0.06	0.12
CFM	0.5–8	> 4	> 4	> 4	> 4	1	2	> 4	> 4	> 4	> 4	1	2	1	2
CTR	0.5–8	4	8	2	4	1	2	2	4	2	4	2	4	1	2
VAN	0.5–64	4	8	4	8	4	8	4	8	4	8	4	8	4	8
AZM	0.5–8	1	2	1	2	1	2	1	2	2	4	1	2	1	2
EM	0.25–32	0.5	1	0.25	0.5	0.25	0.5	0.25	1	0.5	1	0.5	1	0.5	1
TET	0.25–32	2	4	2	4	2	4	2	4	4	8	4	8	2	4
GEN	0.5–32	2	4	2	4	2	4	2	4	2	4	2	4	2	4
CM	0.25–8	0.25	1	0.25	1	0.25	0.5	0.5	1	0.5	1	0.25	0.5	0.5	1
NIT	1–128	16	32	16	32	16	32	16	32	32	64	16	32	16	32
CIP	0.12–16	0.5	1	0.5	1	0.5	1	1	2	1	2	0.5	1	0.5	1
LEV	0.12–16	0.5	1	0.5	1	0.5	1	0.5	1	1	2	0.5	1	0.5	1
CMX	1–128	2	8	2	4	2	4	2	4	2	4	2	4	2	4

MIC Minimum inhibitory concentration, MBC Minimum bactericidal concentration, PG Penicillin G, AMC Amoxicillin-Clavulanic acid, CFM Cefixime, CTR Ceftriaxone, VAN Vancomycin, AZM Azithromycin, EM Erythromycin, TET Tetracycline, GEN Gentamicin, CM Clindamycin, NIT Nitrofurantoin, CIP Ciprofloxacin, LEV Levofloxacin, CMX Co-Trimoxazole

ISSN: 1471-2180