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Fig. 12 | BMC Microbiology

Fig. 12

From: Bioprocessing of Epothilone B from Aspergillus fumigatus under solid state fermentation: Antiproliferative activity, tubulin polymerization and cell cycle analysis

Fig. 12

Flow cytometric analysis of apoptosis in HepG-2cells measured by Annexin V-FITC apoptosis detection Kit. The cells were exposed to IC25 concentration of putative epothilone, the apoptosis was measured after 48 h of incubation. Apoptotic analysis of HepG2-cells without epothilone treatment (A), and in response to treatment with A. fumigatus epothilone (B) and overall quantitative results of apoptosis (C). The cell cycle analysis of the HepG-2 cells without epothilone treatment (D), and in response to treatment with A. fumigatus epothilone (E) and overall quantitative analysis of cell cycle (F). The values were represented by the means, followed by letters a, b within the same column that is a significantly different (ONE Way ANOVA, LSD test, p ≤ 0.05)

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BMC Microbiology

ISSN: 1471-2180

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