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Table 3 Meta-analysis for the proportion of non-toxin virulence factors of S. aureus isolates from DFIs

From: Proportion of toxin and non-toxin virulence factors of Staphylococcus aureus isolates from diabetic foot infection: a systematic review and meta-analysis

Non-toxin virulence factor genes

   

Pooled estimates

 

Heterogeneity test

N

n1

n2

Proportion (%)

95% CI (%)

 

I2 (%)

 

bbp

6

508

267

54.6

(20.3,86.8)

 

98.2

 

cna

6

508

192

45.3

(21.8,69.9)

 

96.2

 

ebps

6

508

234

70.7

(25.9,99.6)

 

98.9

 

clfa

7

549

299

79.8

(28.8,100.0)

 

99.3

 

clfb

6

508

305

86.2

(46.9,100.0)

 

98.8

 

fib

6

508

246

63.1

(31.8,89.5)

 

97.7

 

fnba

5

485

219

73.3

(21.5,100.0)

 

99.2

 

fnbb

6

508

159

35.7

(14.0,60.8)

 

96.3

 

cap5

4

609

174

35.0

(13.4,60.3)

 

96.7

 

cap8

4

609

179

44.6

(10.6,81.8)

 

98.6

 

agr1

9

687

281

38.2

(17.7,60.9)

 

96.9

 

agr2

7

566

102

19.8

(13.0,27.5)

 

74.6

 

agr3

7

566

69

11.7

(6.6,17.8)

 

71.2

 

agr4

7

566

31

3.5

(0.1,9.9)

 

86.8

 

icaa

3

333

113

100.0

(95.6,100.0)

 

47.8

 

icad

3

333

113

100.0

(95.6,100.0)

 

47.8

 

eno

3

163

136

91.7

(70.9,100.0)

 

80.7

 

chp

3

158

90

61.0

(40.8,79.4)

 

78.1

 

scn

3

158

143

71.5

(26.6,99.8)

 

96.1

 
  1. N: number of studies, n1: total number of isolates in all of the studies that report the respective virulence factor; n2: sum of the number of the isolated bacteria that report the respective virulence factor; CI: confidence interval