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Table 2 Meta-analysis for the proportion of toxin virulence factors of S. aureus isolates from DFIs

From: Proportion of toxin and non-toxin virulence factors of Staphylococcus aureus isolates from diabetic foot infection: a systematic review and meta-analysis

Toxin virulence factor genes

   

Pooled estimates

 

Heterogeneity test

N

n1

n2

Proportion (%)

95% CI (%)

 

I2 (%)

 

hla

4

183

118

80.0

(31.0,100.0)

 

97.5

 

hlb

4

360

135

47.0

(29.0,66.0)

 

87.8

 

hlg

5

304

237

88.0

(58.0,100.0)

 

96.6

 

hlgv

5

485

278

79.0

(35.0,100.0)

 

98.9

 

hld

3

158

157

100.0

(97.0,100.0)

 

51.6

 

luk-SF or PVL

15

998

86

11.0

(3.0,21.0)

 

94.1

 

luk-ED

6

469

222

72.0

(42.0,95.0)

 

97.4

 

etA

7

611

7

0.2

(0.0,1.3)

 

21.3

 

etB

6

543

0

0.0

(0.0,0.0)

 

0.0

 

etD

4

353

19

3.8

(0.0,11.6)

 

79.1

 

sea

8

652

173

28.2

(17.9,39.7)

 

87.5

 

seb

6

372

23

4.5

(0.4,11.2)

 

75.5

 

sec

3

208

24

11.3

(2.0,25.1)

 

75.7

 

sed

3

205

52

13.7

(0.2,38.5)

 

90.7

 

see

3

154

0

0.0

(0.0,0.0)

 

0.0

 

seg

4

219

79

28.9

(12.9,47.9)

 

80.5

 

seh

6

372

11

2.5

(0.0,7.4)

 

66.6

 

sei

4

403

120

27.4

(16.5,39.8)

 

79.9

 

sej

3

208

35

8.8

(0.0,40.8)

 

95.1

 

sek

5

375

75

19.2

(0.0,55.3)

 

98.0

 

seq

4

290

72

19.3

(0.0,67.8)

 

98.4

 

tst

8

558

60

9.6

(4.1,16.9)

 

81.6

 

edin-A

3

166

0

9.6

(4.1,16.9)

 

81.6

 

edin-B

3

158

12

4.9

(0.0,23.0)

 

87.1

 
  1. N: number of studies, n1: total number of isolates in all of the studies that report the respective virulence factor; n2: sum of the number of the isolated bacteria that report the respective virulence factor; CI: confidence interval