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Table 1 Demographic and clinical characteristics of pediatric patients in the infantile cholestasis group

From: Alterations in gut microbiota and metabolite profiles in patients with infantile cholestasis

NO

Sex

Age (m)

Course of disease (m)

ALT

U/l

(10–44)

AST

U/l

(10–50)

ALB

g/l

(35–50)

1

F

1.96

1.6

162.1

79.3

44.4

2

F

2.5

2

420

475.6

40.5

3

M

2.43

2

31.8

69

30.3

4

M

1.73

1

88.7

115.3

41.2

5

F

2

1

294.6

335.6

39.1

6

M

5.96

1

178.8

178.4

46.8

7

M

2.63

2

78.2

71.1

38.5

8

M

1.66

1.2

175.9

250.5

38.6

9

F

1.33

1

51.4

102.6

34.6

10

F

2

1

23

44

73

11

M

2

1

93.8

191.1

37.2

12

F

6.13

1

229.6

332.6

37.1

13

F

3

2.5

135

273.7

40.5

14

M

2.83

1

40.7

79.4

37.3

15

F

3

2

56

83

40

16

M

1

1

192

250

38.1

17

F

11

1

192

250

45.1

18

M

2.46

1

103.7

138.6

38.2

19

M

1.86

1

153.1

107.8

44.8

20

M

2.1

2

369

377.8

41.1

 

M/F 11:9

Average: 2.98

Average: 1.4

147.38 ± 108.1

179.12 ± 123.3

41.32 ± 8.1

NO

GGT

U/l

(9–50)

TBIL

μmol/l

(3.4–20.0)

DBIL

μmol/l

(< 3.4)

TBA

μmol/l

(0–10)

WBC

109/l

(4.3–14.2)

Hb

g/l

(110–150)

1

155

103

74.4

99.1

9.61

116

2

82

213.6

123.8

157

11.44

90

3

170

104.2

62.8

62.2

11.25

80

4

142

173.6

107

107.4

7.02

128

5

272

68.7

37.7

48.6

8.73

79

6

2547

317.5

183.3

246.1

19.95

106

7

118

72.39

44.78

74.4

9.2

100

8

119

243.7

139.5

101.5

20.71

102

9

234

221.2

99.6

112.4

9.54

126

10

13

166.3

94.8

347.1

6.31

125

11

192

118.7

74.1

95.9

12.11

99

12

36

162.8

83.9

431.2

19.29

65

13

283

147.2

85.2

122.5

17.36

122

14

231

111.4

57.2

123.6

8.44

112

15

123

58.7

43.8

57.7

6.15

108

16

27

61.2

34.6

58.6

12.22

90

17

27

56.1

34.6

352.8

14.72

104

18

766

168.2

99

179.6

9.71

102

19

43

188.8

86.5

94.6

12.55

107

20

59

243.7

138.6

75.9

11.33

108

 

287.4 ± 543.2

142.74 ± 81.6

80.04 ± 46.04

140.96 ± 113.44

11.88 ± 4.3

103.45 ± 16.18

NO

PLT

109/l

(183–614)

CRP

mg/l

(< 8)

PT

s

(10–13)

APTT

s

(22.3–32.5)

INR

(0.9–1.2)

BA

μmmol/l

(11–40)

Lac

mmol/l

(0.5–2.2)

1

326

0.5

11.4

29.6

0.99

98.21

2.7

2

596

0.42

10.5

34.2

0.91

10

1.4

3

526

0.39

14.2

48.9

1.26

71.93

1.9

4

288

0.47

13.3

54.6

1.17

10

1.8

5

229

3.6

9.9

31.2

0.85

47.92

2.8

6

330

0.69

10.3

27.6

0.89

70.16

1.6

7

480

0.43

10.9

31.3

0.94

23.2

2.9

8

448

0.5

10.9

36.1

0.94

7.48

2

9

338

3

11.2

36.9

0.97

46.47

2.2

10

410

0.78

10.5

24.5

0.91

38.19

1.7

11

570

0.43

11.5

33.2

1

17.72

0.6

12

381

0.5

11

24.8

0.95

23.8

2.1

13

396

1

11.7

34.9

1.02

54.04

3.3

14

350

0.44

12.8

38.7

1.12

46.8

1.6

15

355

0.43

11.5

29.3

1

46.44

0.9

16

383

0.5

10.3

27.5

0.9

49.5

1.6

17

337

0.43

10.2

26.4

0.88

51.89

1.6

18

457

0.5

9.2

27.1

0.78

29.3

1.7

19

449

0.45

10.5

26.4

0.91

54.64

1.8

20

533

0.78

11.9

31.5

1.04

56

3.1

 

409.1 ± 94.56

0.81 ± 0.85

11.19 ± 1.1

32.74 ± 7.53

0.97 ± 0.11

42.68 ± 22.67

1.97 ± 0.68

  1. Continuous variables are expressed as mean ± standard deviation
  2. Abbreviations NO number, M Male, F Female, m month, ALT Alanine aminotransferase, AST Aspartate aminotransferase ALB Albumin, GGT Glutamyl transpeptidase TBIL: Total bilirubin DBIL Direct bilirubin, TBA Total bile acid, WBC white blood cell count, Hb Hemoglobin, PLT Platelet count, CRP C-reactive protein, PT Prothrombin time, APTT Activated partial thromboplastin time, INR International normalized ratio, BA Blood ammonia, Lac Blood lactic acid
  3. Reference values are in parentheses