Fig. 2
From: Alterations in gut microbiota and metabolite profiles in patients with infantile cholestasis
Profiling of gut microbiota-derived metabolites in the infantile cholestasis (IC) and control (CON) groups. A Categorical and quantitative distribution of metabolites across all samples; B. Distribution of metabolites in different groups; C. univariate statistical analysis of differential metabolites. Red dots on the right: upregulated metabolites in the IC compared to CON group, blue dots on the left: downregulated metabolites, gray dots (NONE): metabolites that did not meet the threshold requirements; D. multivariate statistical analysis of differential metabolites; x-axis: Pearson's correlation coefficients between each metabolite and first principal component (P1), y-axis: contribution of metabolites to the model discrimination (variable importance in projection; VIP). Green dots: metabolites with VIP score > 1; 2E. box plot showing the top nine differential metabolites