Table 3 Metabolites that correlated to the observed antimalarial activity of the active extracts as predicted using the OPLS-DA-derived S-Plots

1

P

291.049

2.117525

Juglomycin E

C₁₄H₁₀O₇

273.18; 171.10

Streptomyces sp.

Quinones

[44]

2

P

517.170

4.4354464

Didemethylmutactimycin

C₂₆H₂₈O₁₁

417

Streptomyces sp. GW 60/157

Quinones

[28]

3

N

325.108

4.0799119

1,3,6-Trihydroxy-8-(3-methylbutyl) anthraquinone

C₁₉H₁₈O₅

323.39; 297.7; 281.11

Streptomyces No. 1128

Quinones

[51]

4

N

269.044

3.7012692

ω-Hydroxyaloesaponarin II

C₁₅H₁₀O₅

225.10; 177.05; 213.11

Streptomyces sp. M097

Quinones

[53]

5

P

564.245

3.5117262

Saframycin Y3

C₂₉H₃₃N₅O₇

502.17; 461.10; 415.19

S. lavendulae

Quinones

[47]

6

N

355.118

3.9897705

X 14881B

C₂₀H₂₀O₆

–

Streptomyces sp. Y-83,30,683

Anthracene

[27]

7

N

197.081

2.701041

2-Butyl-4-(hydroxymethyl)-3-furancarboxylic acid

C₁₀H₁₄O₄

133.54; 91.41; 57.28

S. coelicolor

Lactones

[24]

8

P

351.228

4.029025

Nitropyrrolin A

C₁₉H₃₀N₂O₄

249.18; 197.12; 67.05

Streptomyces sp. CNQ-509

Nitropyrrolins

[54]