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Table 2 The 15 most important VIPs

From: Targeting antimalarial metabolites from the actinomycetes associated with the Red Sea sponge Callyspongia siphonella using a metabolomic method

No

Ionization

m/z

Rt

Name

formula

Source

Class

Reference

1

N

197.0815

2.70104

(a)2-Butyl-4-(hydroxymethyl)-3-furancarboxylic acid

C10H14O4

Streptomyces coelicolor

Lactones

[24]

(b)4-(Hydroxymethyl)-2-(2-methylpropyl)-3-furancarboxylic acid

[25]

2

N

355.1184

3.98977

Antibiotic X 14881B

C20H20O6

Streptomyces sp.

Anthracene

[27]

3

N

567.2282

3.652877

Chinikomycin A

C31H37ClN2O6

Streptomyces lavendulae

Manumycins

[49]

4

p

496.3411

5.947817

8,9-Dihydroindanomycin

C31H45NO4

Streptomyces galbus

Quinones

[50]

5

N

325.1080

4.079911

1,3,6-Trihydroxy-8-(3-methylbutyl) anthraquinone

C19H18O5

Streptomyces No. 1128

[51]

6

N

487.3422

4.804455

4,23-Dihydroxy-22-oxo-3,4-seco-12-oleanen-3-oic acid

C30H48O5

Streptomyces sp. GT 44003

Triterpenoids

[52]

7

P

517.1709

4.435446

(a)Didemethylmutactimycin

C26H28O11

Streptomyces sp. GW 60/157

Quinones

[28]

(b)8-Demethoxy-2'-de-O-methylsteffimycin D

Streptomyces steffisburgensis NRRL 3193

[29]

8

P

375.2021

3.8968476

Antibiotic SEN 366D1; 2-Hydroxy, 2,3-dihydro

C18H30O8

Streptomyces sp. SEN366-BP577

  

9

N

269.0449

3.701269

ω-Hydroxyaloesaponarin II

C15H10O5

Streptomyces sp. M097

Quinones

[53]

10

p

439.2228

4.252196

(a)Streptophenazine F

C25H30N2O5

marine-derived Streptomyces sp. strain HB202

Phenazines

[31]

(b)Streptophenazine G

11

P

564.2456

3.511726

Saframycin Y3

C29H33N5O7

Streptomyces lavendulae

Quinones

[47]

12

P

351.2282

4.029025

Nitropyrrolin A

C19H30N2O4

marine-derived Streptomyces sp. CNQ-509

Nitropyrrolins

[54]

13

P

425.2079

3.6336655

(a)JBIR 107

C24H28N2O5

marine-derived Streptomyces tateyamensis NBRC 105047

 

[30]

(b)Streptophenazine A

marine-derived Streptomyces sp. strain HB202

Phenazines

[31]

(c)Streptophenazine B

14

N

569.2436

3.472232

Benthophoenin

C37H34N2O4

Streptomyces prunicolor

Phenazines

[55]

15

N

325.2015

3.8514833

(a)Albocycline M6

C18H30O5

Streptomyces bruneogriseus

Macrolides

[32]

(b)Albocycline M3

(c)Antibiotic A 121

Streptomyces sp.

non-polyene antibiotic

[33]