Investigating the antimicrobial activity, cytotoxicity, and action mechanism of acylated and amidated derivatives of AurH1 antifungal peptide

Table 2 FIC indexes and their Interpretations for peptides-antibiotics against C.abicans, C. glabrata, and C. krusei

Combination		C. abicans		C. glabrata		C. krusei
Combination		FIC index	Interpretation	FIC index	Interpretation	FIC index	Interpretation
Ac-AurH1	Flu^a	0.5	Additive	6	Indifference	2.5	Indifference
Ac-AurH1	Nys^b	8.2	Antagonist	5.5	Antagonist	10.5	Indifference
Ac-AurH1	Amph^c	0.489	Synergy	0.123	Synergy	0.06	Synergy
AurH1-NH₂	Flu^a	1.25	Indifference	3	Indifference	1.55	Indifference
AurH1-NH₂	Nys^b	1.15	Indifference	5.5	Antagonist	7	Antagonist
AurH1-NH₂	Amph^c	0.24	Synergy	0.25	Synergy	0.25	Synergy

ISSN: 1471-2180