Fig. 4From: Antimicrobial peptidase lysostaphin at subinhibitory concentrations modulates staphylococcal adherence, biofilm formation, and toxin productionAdherence of staphylococcal strains (A) MSSA 25923 and (B) MRSA 33591 to HVEC. Subconfluent HVEC cell monolayers were infected with a suspension at a cell: bacterial ratio of 1: 200 in the presence or absence of varying concentrations of APLss or Van. HVEC were lysed to release any clinging bacteria, and then plated in serial dilutions on LB-agar plates. The bacteria adhering to the HVEC cells were quantified. The data are shown as mean ± SEM. Bars marked with a (*), (***) or (****) indicate statistical significance at the p < 0.05, p < 0.001, and p < 0.0001 levels, respectively. Abbreviations: APLss, antimicrobial peptidase lysostaphin; HVEC, human vaginal epithelial cells; MRSA, methicillin-resistant Staphylococcus aureus; MSSA, methicillin-sensitive Staphylococcus aureus; Van, vancomycinBack to article page