Fig. 3
From: Identification of disease-related genes in Plasmodium berghei by network module analysis
Identification of genes contributing to infect mice in P. berghei. (A) Heatmap showing the enrichment of 63 clusters enriched in rodent malaria parasites. Cluster1, Cluser3, Cluster305, and Cluster6 are the top four clusters with cluster value ≥ 40 in P. berghei. Green, black, and red indicate cluster values equal to zero, one, and higher than five, respectively. (B) Domain architectures of proteins from the top four clusters. SP, signal peptide. TM, transmembrane domain. PIR, Plasmodium Interspersed Repeat. (C) Radar plot illustrating the phenotypic manifestation of 30 rodent Plasmodium specific genes after disruption obtained from RMgmDB.