Fig. 2

Map of Ligilactobacillus salivarius genome. The analysis was performed with Circos v0.64 software (http://circos.ca/). The first circle was the mark of genome size. The second and third circles were functional classification on the coding DNA sequence (CDS) in positive-and negative-chains, using the annotation of Clusters of Orthologous Group (COG). The fourth circle was the ribosomal RNA (rRNA) and transport RNA (tRNA). The fifth cycle was the content of nucleic acid base G and C. The higher the peak value meant the greater the content of G and C, towards inner blue part and the red part towards outer space indicates that the content of G and C was lower and higher than average level. The six circle was the value of GC skew, which was calculated G-C/G + C. The inner green part meant the value was positive, which the content of G was higher than C, represented the positive chain more tendency to transport the CDS. The inner brown part meant the value was negative, which the content of G was negative than C, represented the negative chain more tendency to transport the CDS