The fungal quorum-sensing molecule, farnesol, regulates the immune response of vaginal epithelial cells against Candida albicans

Table 1 The expression levels of cytokine of vaginal epithelial cells after co-incubation with farnesol

Group*	L-2 (pg/mL)	IL-4 (pg /L)	IL-6 (pg /L)	IL-8 (pg /L)	IL-17 (pg /L)
V	46.81 ± 3.07	37.65 ± 0.85	27.96 ± 0.15	29.86 ± 0.55	60.03 ± 2.71
V + F50	50.42 ± 2.81	25.58 ± 0.88	24.17 ± 0.20	21.94 ± 1.70	36.87 ± 2.45
V + C	38.48 ± 2.84	23.12 ± 0.76	18.91 ± 0.65	12.41 ± 0.06	30.65 ± 1.87
V + C + F25	28.86 ± 2.45	28.25 ± 0.89	17.91 ± 1.18	9.95 ± 0.43	24.81 ± 2.14
V + C + F50	21.22 ± 2.26	34.50 ± 0.49	16.80 ± 0.83	9.82 ± 0.90	46.88 ± 1.89

* V, VK2 cells cultivated alone; V + F50, cultured with 50µM farnesol alone; V + C, VK2 cells infected with C. albicans for 12 h; V + C + F25/50, VK2 cells infected as well as treated with 25/50µM farnesol for another 24 h. Cytokine levels of the supernatants were measured after 36 h for all the treatments

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