Table 2 Evaluation of blood parameters 72 h after the challenge
Parameter | Hematological reference values | Result of normal BalB/c Mice | group A (× 106 mm3) Median ± SD | Group B1 (× 106 mm3) Median ± SD | Group B2 (× 106 mm3) Median ± SD | Group C1 (× 106 mm3) Median ± SD | Group C2 (× 106 mm3) Median ± SD |
|---|---|---|---|---|---|---|---|
Leukocytes (× 103 /mm3) | 1500–4800 | 2.9 (× 106 mm3) | 6.160 1.15 | 3.430 1.16 | 3.950 0.84 | 3.350 1.5 | 5.100 1.04 |
Segmented Neutrophils(/mm3) | 300 – 900 | 0.55 (x106mm3) | 4.46 1.2 | 0.85 0.4 | 1.51 0.3 | 0.79 0.5 | 2.55 0.2 |
Monocytes (/mm3) | 0 – 200 | 0.048 (x106mm3) | 0.031 0.01 | 0.044 0.02 | 0.043 0.01 | 0.04 0.01 | 0.040 0.02 |
Lymphocytes(/mm3) | 900 – 3200 | 2.084 (x106mm3) | 1.370 1 | 2.309 1 | 1.870 0.8 | 2.2 0.85 | 1.976 1.15 |
Platelets (× 103/mm3) | 325–888 | 590 | 387 44.3 | 612 48 | 610 45 | 670 188 | 420 23 |
Red blood cells (× 106/mm3) | 7.1 – 9.5 | 8 | 7.93 1.1 | 8.19 1.05 | 8.05 1 | 7.59 1.1 | 7.81 0.9 |
Hemoglobin (g/dL) | 11.6 – 15.8 | 12 | 12.1 1.3 | 13.3 1.7 | 13.1 1 | 12.6 1.2 | 11.9 0.6 |
MCV (fL) | 41.5 – 57.4 | 51 | 46 5.56 | 53.8 7.6 | 46.8 6.02 | 52.9 4.7 | 49.9 6.02 |
MCH (pg) | 14.1 – 18.4 | 16 | 15.4 1.35 | 16.1 1.75 | 15.9 1.27 | 15.9 2.1 | 16 1.3 |
MCHC (%) | 30.5 – 34.2 | 32 | 27.3 3.7 | 32.2 1.5 | 32 1.3 | 31.6 1.7 | 31.8 0.72 |