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Fig. 7 | BMC Microbiology

Fig. 7

From: Characterization of novel bacteriophage PSKP16 and its therapeutic potential against β-lactamase and biofilm producer strain of K2-Hypervirulent Klebsiella pneumoniae pneumonia infection in mice model

Fig. 7

Sections of pathological changes micrograph of lung in challenge BALB/c mice groups (3 mice/group/timepoint), from group A (AE) and group B1 (F) sacrificed at 48 h and 7th day post challenge (haematoxylin and eosin stain). A Lung—Hemorrhage in mice of group A: A Erythrocytes are present in the perivascular space around a pulmonary vein at 48 h post challenge. B (48 h), C and E (7th day), Necrosis of the alveolar parenchyma with interstitial infiltration of neutrophils, and macrophages. D Congested blood vessels with moderate to severe infiltration of neutrophils in the lung parenchyma. F Lung sections from Bhvkp-infected mice which was recovered by treatment with phage PSKP16 in 7th day post challenge. Decreased white blood cells were observed

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