Characteristics and potential clinical applications of the extracellular vesicles of human pathogenic Fungi

BMC Microbiology

Table 1 Functional classification of proteins enriched in fungal extracellular vesicles (EVs)

	C. neoformans	C. gattii	C. albicans	NAC	P. braziliensis	A. fumigatus	H. capsulatum	T. marneffei	A. infectoria	S. cerevisiae
Cell metabolism	√		√	√	√	√	√	√	√	√
Cell wall formation	√		√	√		√	√			√
Signal transduction	√			√	√		√	√
Stress response			√	√	√	√	√	√		√
Transcription and translation				√	√					√
Enzymes	√		√	√	√	√	√	√
Pathogenicity	√	√	√			√		√	√
Heat shock proteins	√							√	√	√
Immunogenic proteins	√								√
Biofilm biogenesis			√
References	[9, 21, 57]	[15]	[30, 35, 54, 58, 59, 70,71,72]	[60, 70]	[8]	[73, 74]	[44, 55, 75, 76]	[77]	[63]	[10, 20, 39, 64,65,66,67]

ISSN: 1471-2180