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Table 5 Effect of PaβN (phenylalanine-arginine beta-naphthylamide) on MICs of ciprofloxacin in selected ciprofloxacin-resistant E. coli isolates

From: Prevalence and mechanisms of ciprofloxacin resistance in Escherichia coli isolated from hospitalized patients, healthy carriers, and wastewaters in Iran

 

Molecular characteristics of the isolates

MIC (µg/mL) without PAβN

MIC (µg/mL) with PAβN

Gene pattern

Mutations

par C

gyr B

gyr A

1

oqxA/B

-

-

 + 

32

16

2

oqxA/B

-

-

-

128

64

3

oqxA/B

-

-

-

128

64

4

oqxA/B

-

-

-

64

32

5

oqxA/B

-

-

-

16

8

6

no oqxA/B

-

-

 + 

8

8

7

no oqxA/B

-

-

-

256

256