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Table 4 Profiles of PMQR genes and ciprofloxacin MIC levels in ciprofloxacin-resistant E. coli isolates

From: Prevalence and mechanisms of ciprofloxacin resistance in Escherichia coli isolated from hospitalized patients, healthy carriers, and wastewaters in Iran

Profile No

Gene combination

Gene No

Frequency N = 97, n (%)

Isolates N = 97, n (%)

MIC50 µg/mL

MIC90 µg/mL

1

oqxB

1

4 (4.12)

35 (36.08)

16

32

2

aac (6’)-Ib-cr

5 (5.15)

 

32

64

3

qnrS

25 (25.77)

 

32

64

4

qepA

1 (1.03)

 

128

128

5

oqxB, qnrB

2

1 (1.03)

41 (42.26)

16

16

6

oqxA, oqxB

5 (5.15)

 

64

128

7

aac (6’)-Ib-cr, oqxA

1 (1.03)

 

64

64

8

aac (6’)-Ib-cr, oqxB

3 (3.09)

 

32

64

9

qnrS, qnrB

4 (4.12)

 

4

32

10

qnrS, oqxB

9 (9.27)

 

4

32

11

qnrS, aac (6’)-Ib-cr

18 (18.55)

 

64

128

12

aac (6’)-Ib-cr, oqxA, oqxB

3

1 (1.03)

17 (17.52)

2

2

13

qnrS, oqxB, oqxA

2 (2.06)

 

2

4

14

aac (6’)-Ib-cr, oqxA, qnrS

5 (5.15)

 

64

256

15

qnrS, aac (6’)-Ib-cr, qnrB

4 (4.12)

 

16

32

16

qnrS, aac (6’)-Ib-cr, oqxB

5 (5.15)

 

32

64