Table 2 Association between missense mutations in GyrA, ParC, and ParE subunits and ciprofloxacin MIC levels in ciprofloxacin-resistant E. coli isolates

1

Ser-83 → Leu, Asp-87 → Asn

Ser-80 → Ile

ND

3

64

128

2

Ser-83 → Leu, Asp-87 → Asn

Ser-80 → Ile, Glu-84 → Val

-^b

2

8

32

3

Ser-83 → Leu, Asp-87 → Asn

Ser-80 → Ile, Glu-84 → Val

ND

4

64

128

4

Ser-83 → Leu, Asp-87 → Asn

Glu-84 → Val

ND

1

64

64

5

Ser-83 → Leu, Asp-87 → Asn

-

ND

10

32

64

6

Ser-83 → Leu, Asp-87 → Asn

-

-

4

4

8

7

Ser-83 → Leu, Asp-87 → Asn

-

Ser-458 → Ala

2

32

128

8

Ser-83 → Leu

-

-

1

4

4

9

-

-

ND

2

16

32

10

-

-

-

4

4

32