Fig. 6

PPI analysis by the STRING. (a) The diagram of purine metabolism. Nodes were colored with specific role: Purine nucleotide salvage (red), purine ribonucleoside salvage (blue), IMP salvage (green), GMP salvage (yellow) and not purine salvage pathway (all colors). (b) Ruminococcus gnavus enriched the proteins of xhdB and xdhA without the proteins involved in salvage pathway. (c) Bifidobacterium bifidum enriched no the proteins of salvage pathway. (d) Lactobacillus vaginalis enriched in Purine nucleotide salvage (red), Purine ribonucleoside salvage, IMP salvage, GMP salvage and had four related proteins (e) Allobaculum enriched three proteins of salvage pathway. Bacteroides acidifaciens (f) and Clostridium botulinum (g) enriched two proteins of salvage pathway. xhd: xanthine dehydrogenase; apt: Adenine phosphoribosyltransferase; hpt: hypoxanthine phosphoribosyltransferase; pur: Phosphoribosylaminoimidazolecarboxamide formyltransferase